Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning.

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Title: Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning.
Authors: Lasso G; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA. Electronic address: gorka.lasso@gmail.com., Grodus M; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY 10032, USA., Valencia E; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA., DeJesus V; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA., Liang E; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY 10032, USA., Delwel I; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA., Bortz RH 3rd; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA., Lupyan D; Schrödinger Inc., Cambridge, MA 02142, USA., Ehrlich HY; One Health Institute, School of Veterinary Medicine, University of California, Davis, CA 95616, USA., Castellanos AA; Cary Institute of Ecosystem Studies, Millbrook, NY 12545, USA., Gazzo A; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Wells HL; Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA., Wacharapluesadee S; Thai Red Cross Emerging Infectious Diseases Clinical Center, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand., Tremeau-Bravard A; One Health Institute, School of Veterinary Medicine, University of California, Davis, CA 95616, USA., Seetahal JFR; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66502, USA., Hughes T; Conservation Medicine, 47000 Sungai Buloh, Selangor, Malaysia; EcoHealth Alliance, New York, NY 10018, USA., Lee J; Conservation Medicine, 47000 Sungai Buloh, Selangor, Malaysia; EcoHealth Alliance, New York, NY 10018, USA., Lee MH; Conservation Medicine, 47000 Sungai Buloh, Selangor, Malaysia; EcoHealth Alliance, New York, NY 10018, USA., Sjodin AR; Department of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT 06269, USA., Geldenhuys M; Centre for Viral Zoonoses, Department of Medical Virology, University of Pretoria, Pretoria 0001, South Africa., Mortlock M; Centre for Viral Zoonoses, Department of Medical Virology, University of Pretoria, Pretoria 0001, South Africa., Navarrete-Macias I; Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA., Gilardi K; One Health Institute, School of Veterinary Medicine, University of California, Davis, CA 95616, USA., Willig MR; Department of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT 06269, USA; Center for Environmental Sciences and Engineering, Institute of the Environment, University of Connecticut, Storrs, CT 06269, USA., Nava AFD; Fundação Oswaldo Cruz-Fiocruz, Instituto Leônidas & Maria Deane, Laboratório de Ecologia de Doenças Transmissíveis na Amazônia - EDTA, Manaus 69.057-070, AM, Brazil., Loh EH; Division of Natural Sciences and Mathematics, Transylvania University, Lexington, KY 40508, USA., Asrat M; Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA., Smiley-Evans T; One Health Institute, School of Veterinary Medicine, University of California, Davis, CA 95616, USA., Magesa WS; College of Veterinary Medicine and Biomedical Sciences, Sokoine University of Agriculture, P.O. Box 3021, Morogoro, Tanzania., Zikankuba S; College of Veterinary Medicine and Biomedical Sciences, Sokoine University of Agriculture, P.O. Box 3021, Morogoro, Tanzania., Wolking D; One Health Institute, School of Veterinary Medicine, University of California, Davis, CA 95616, USA., Suzán G; Laboratorio de Ecología de Enfermedades y Una Salud, Departamento de Etología, Fauna Silvestre y Animales de Laboratorio, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Ciudad de México, 04510, Mexico., Ojeda-Flores R; Laboratorio de Ecología de Enfermedades y Una Salud, Departamento de Etología, Fauna Silvestre y Animales de Laboratorio, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Ciudad de México, 04510, Mexico., Carrington CVF; Department of Preclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Republic of Trinidad and Tobago., Islam A; Gulbali Research Institute, Charles Sturt University, Wagga Wagga, NSW 2678, Australia., Epstein JH; EcoHealth Alliance, New York, NY 10018, USA., Markotter W; Centre for Viral Zoonoses, Department of Medical Virology, University of Pretoria, Pretoria 0001, South Africa., Johnson CK; One Health Institute, School of Veterinary Medicine, University of California, Davis, CA 95616, USA., Goldstein T; One Health Institute, Colorado State University, Fort Collins, CO 80523, USA., Han BA; Cary Institute of Ecosystem Studies, Millbrook, NY 12545, USA., Mazet JAK; One Health Institute, School of Veterinary Medicine, University of California, Davis, CA 95616, USA., Jangra RK; Department of Microbiology and Immunology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA; Center for Applied Immunology and Pathological Processes, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA; Center of Excellence for Emerging Viral Threats, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA. Electronic address: rohit.jangra@lsuhs.edu., Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA. Electronic address: kartik.chandran@einsteinmed.edu., Anthony SJ; Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. Electronic address: sjanthony@ucdavis.edu.
Source: Cell host & microbe [Cell Host Microbe] 2025 Feb 12; Vol. 33 (2), pp. 294-313.e11. Date of Electronic Publication: 2025 Jan 15.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101302316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1934-6069 (Electronic) Linking ISSN: 19313128 NLM ISO Abbreviation: Cell Host Microbe Subsets: MEDLINE
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