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Pegcetacoplan for the treatment of geographic atrophy due to age-related macular degeneration: a plain language summary of OAKS and DERBY clinical studies.

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Title: Pegcetacoplan for the treatment of geographic atrophy due to age-related macular degeneration: a plain language summary of OAKS and DERBY clinical studies.
Authors: Heier JS; aOphthalmic Consultants of Boston, Boston, MA, USA., Lad EM; bDepartment of Ophthalmology, Duke University Medical Center, Durham, NC, USA., Holz FG; cDepartment of Ophthalmology, University of Bonn, Bonn, Germany., Rosenfeld PJ; dDepartment of Ophthalmology, University of Miami, Miami, FL, USA., Guymer RH; eCentre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia., Boyer D; fRetina Vitreous Associates Medical Group, Los Angeles, CA, USA., Grossi F; gApellis Pharmaceuticals, Waltham, MA,USA., Baumal CR; gApellis Pharmaceuticals, Waltham, MA,USA., Korobelnik JF; hService d'Ophtalmologie, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France.; iOphthalmology Department, University of Bordeaux, Bordeaux,France., Slakter JS; jDepartment of Ophthalmology, New York University, New York, NY, USA., Waheed NK; kNew England Eye Center, Boston, MA, USA., Metlapally R; gApellis Pharmaceuticals, Waltham, MA,USA., Pearce I; llDepartment of Ophthalmology Royal Liverpool University Hospital, Liverpool, UK., Steinle N; mCalifornia Retina Consultants, Santa Barbara, CA, USA., Francone AA; nCharles Centro Oftalmológico, Buenos Aires, Argentina., Hu A; oCumberland Valley Retina Consultants, Hagerstown, MD, USA., Lally DR; pNew England Retina Consultants, Springfield, MA, USA., Deschatelets P; gApellis Pharmaceuticals, Waltham, MA,USA., Francois C; gApellis Pharmaceuticals, Waltham, MA,USA., Bliss C; gApellis Pharmaceuticals, Waltham, MA,USA., Staurenghi G; qDepartment of Biomedical and Clinical Science, Ospedale Luigi Sacco University of Milan, Milan, Italy., Monés J; rInstitut de la Màcula, Centro Médico Teknon and Barcelona Macula Foundation: Research for Vision,Centro Médico Teknon, Barcelona, Spain., Singh RP; sCenter for Ophthalmic Bioinformatics, Cleveland Clinic, Cleveland, OH, USA., Ribeiro R; gApellis Pharmaceuticals, Waltham, MA,USA., Wykoff CC; tRetina Consultants of Texas, Blanton Eye Institute, and Houston Methodist Hospital, Houston, TX, USA.
Source: Immunotherapy [Immunotherapy] 2025 Jun; Vol. 17 (9), pp. 609-623. Date of Electronic Publication: 2025 Jan 17.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101485158 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-7448 (Electronic) Linking ISSN: 1750743X NLM ISO Abbreviation: Immunotherapy Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: Pegcetacoplan for the treatment of geographic atrophy due to age-related macular degeneration: a plain language summary of OAKS and DERBY clinical studies.
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  Data: <searchLink fieldCode="AU" term="%22Heier+JS%22">Heier JS</searchLink>; aOphthalmic Consultants of Boston, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lad+EM%22">Lad EM</searchLink>; bDepartment of Ophthalmology, Duke University Medical Center, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Holz+FG%22">Holz FG</searchLink>; cDepartment of Ophthalmology, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Rosenfeld+PJ%22">Rosenfeld PJ</searchLink>; dDepartment of Ophthalmology, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Guymer+RH%22">Guymer RH</searchLink>; eCentre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Boyer+D%22">Boyer D</searchLink>; fRetina Vitreous Associates Medical Group, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Grossi+F%22">Grossi F</searchLink>; gApellis Pharmaceuticals, Waltham, MA,USA.<br /><searchLink fieldCode="AU" term="%22Baumal+CR%22">Baumal CR</searchLink>; gApellis Pharmaceuticals, Waltham, MA,USA.<br /><searchLink fieldCode="AU" term="%22Korobelnik+JF%22">Korobelnik JF</searchLink>; hService d'Ophtalmologie, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France.; iOphthalmology Department, University of Bordeaux, Bordeaux,France.<br /><searchLink fieldCode="AU" term="%22Slakter+JS%22">Slakter JS</searchLink>; jDepartment of Ophthalmology, New York University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Waheed+NK%22">Waheed NK</searchLink>; kNew England Eye Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Metlapally+R%22">Metlapally R</searchLink>; gApellis Pharmaceuticals, Waltham, MA,USA.<br /><searchLink fieldCode="AU" term="%22Pearce+I%22">Pearce I</searchLink>; llDepartment of Ophthalmology Royal Liverpool University Hospital, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Steinle+N%22">Steinle N</searchLink>; mCalifornia Retina Consultants, Santa Barbara, CA, USA.<br /><searchLink fieldCode="AU" term="%22Francone+AA%22">Francone AA</searchLink>; nCharles Centro Oftalmológico, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Hu+A%22">Hu A</searchLink>; oCumberland Valley Retina Consultants, Hagerstown, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lally+DR%22">Lally DR</searchLink>; pNew England Retina Consultants, Springfield, MA, USA.<br /><searchLink fieldCode="AU" term="%22Deschatelets+P%22">Deschatelets P</searchLink>; gApellis Pharmaceuticals, Waltham, MA,USA.<br /><searchLink fieldCode="AU" term="%22Francois+C%22">Francois C</searchLink>; gApellis Pharmaceuticals, Waltham, MA,USA.<br /><searchLink fieldCode="AU" term="%22Bliss+C%22">Bliss C</searchLink>; gApellis Pharmaceuticals, Waltham, MA,USA.<br /><searchLink fieldCode="AU" term="%22Staurenghi+G%22">Staurenghi G</searchLink>; qDepartment of Biomedical and Clinical Science, Ospedale Luigi Sacco University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Monés+J%22">Monés J</searchLink>; rInstitut de la Màcula, Centro Médico Teknon and Barcelona Macula Foundation: Research for Vision,Centro Médico Teknon, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Singh+RP%22">Singh RP</searchLink>; sCenter for Ophthalmic Bioinformatics, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Ribeiro+R%22">Ribeiro R</searchLink>; gApellis Pharmaceuticals, Waltham, MA,USA.<br /><searchLink fieldCode="AU" term="%22Wykoff+CC%22">Wykoff CC</searchLink>; tRetina Consultants of Texas, Blanton Eye Institute, and Houston Methodist Hospital, Houston, TX, USA.
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  Data: <searchLink fieldCode="JN" term="%22101485158%22">Immunotherapy</searchLink> [Immunotherapy] 2025 Jun; Vol. 17 (9), pp. 609-623. <i>Date of Electronic Publication: </i>2025 Jan 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101485158 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1750-7448 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221750743X%22">1750743X </searchLink><i>NLM ISO Abbreviation: </i>Immunotherapy <i>Subsets: </i>MEDLINE; In Process
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        Value: 10.1080/1750743X.2025.2449760
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        Text: English
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