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Establishing minimally important difference thresholds for lesion counts in acne clinical studies.

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Title: Establishing minimally important difference thresholds for lesion counts in acne clinical studies.
Authors: Barbieri JS; Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address: jbarbieri@bwh.harvard.edu., Ellenberg SS; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania., Tierney A; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania., VanderBeek SB; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania., Papadopoulos M; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania., Mason J; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania., Mason A; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania., Dattilo J; Clinical Research Collaboration Unit, University of Pennsylvania, Philadelphia, Pennsylvania., Margolis DJ; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.
Source: Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2025 May; Vol. 92 (5), pp. 1117-1119. Date of Electronic Publication: 2025 Jan 15.
Publication Type: Journal Article
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 7907132 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6787 (Electronic) Linking ISSN: 01909622 NLM ISO Abbreviation: J Am Acad Dermatol Subsets: MEDLINE; In Process
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  Data: <searchLink fieldCode="AU" term="%22Barbieri+JS%22">Barbieri JS</searchLink>; Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address: jbarbieri@bwh.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Ellenberg+SS%22">Ellenberg SS</searchLink>; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Tierney+A%22">Tierney A</searchLink>; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22VanderBeek+SB%22">VanderBeek SB</searchLink>; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Papadopoulos+M%22">Papadopoulos M</searchLink>; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Mason+J%22">Mason J</searchLink>; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Mason+A%22">Mason A</searchLink>; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Dattilo+J%22">Dattilo J</searchLink>; Clinical Research Collaboration Unit, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Margolis+DJ%22">Margolis DJ</searchLink>; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mosby%22">Mosby </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7907132 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-6787 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201909622%22">01909622 </searchLink><i>NLM ISO Abbreviation: </i>J Am Acad Dermatol <i>Subsets: </i>MEDLINE; In Process
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              Text: 2025 May
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