First generation vanadium-based PTEN inhibitors: Comparative study in vitro and in vivo and identification of a novel mechanism of action.

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Title: First generation vanadium-based PTEN inhibitors: Comparative study in vitro and in vivo and identification of a novel mechanism of action.
Authors: Premeti K; Department of Pharmacology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece., Tsipa D; Department of Pharmacology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece., Nadalis AE; Department of Pharmacology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece., Papanikolaou MG; Department of Chemistry, University of Ioannina, Ioannina 45110, Greece; Department of Chemistry, University of Cyprus, Nicosia 2109, Cyprus., Syropoulou V; Department of Pharmacology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece., Karagkiozeli KD; Department of Pharmacology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece., Aggelis G; Department of Pharmacology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece., Iordanidou E; Department of Chemistry, University of Ioannina, Ioannina 45110, Greece., Labrakakis C; Department of Biological Applications and Technology, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece; Institute of Biosciences, University Research Center Ioannina, University of Ioannina, Ioannina, Greece., Pappas P; Department of Pharmacology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece., Keramidas AD; Department of Chemistry, University of Cyprus, Nicosia 2109, Cyprus., Antoniou K; Department of Pharmacology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece; Institute of Biosciences, University Research Center Ioannina, University of Ioannina, Ioannina, Greece., Doulias PT; Department of Chemistry, University of Ioannina, Ioannina 45110, Greece; Institute of Biosciences, University Research Center Ioannina, University of Ioannina, Ioannina, Greece., Kabanos TA; Department of Chemistry, University of Ioannina, Ioannina 45110, Greece., Leondaritis G; Department of Pharmacology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece; Institute of Biosciences, University Research Center Ioannina, University of Ioannina, Ioannina, Greece. Electronic address: gleondar@uoi.gr.
Source: Biochemical pharmacology [Biochem Pharmacol] 2025 Mar; Vol. 233, pp. 116756. Date of Electronic Publication: 2025 Jan 15.
Publication Type: Journal Article; Comparative Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-2968
DOI:10.1016/j.bcp.2025.116756