A Phase II Trial of Onapristone and Fulvestrant for Patients With ER+ and HER2- Metastatic Breast Cancer.

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Title: A Phase II Trial of Onapristone and Fulvestrant for Patients With ER+ and HER2- Metastatic Breast Cancer.
Authors: Kamaraju S; Froedtert & Medical College of Wisconsin, Cancer Center, Milwaukee, WI, 53226. Electronic address: skamaraju@mcw.edu., Fowler AM; Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI 53792-3252., Tarima S; Froedtert & Medical College of Wisconsin, Cancer Center, Milwaukee, WI, 53226; Department of Biostatistics, Medical College of Wisconsin, Milwaukee, WI 53226., Chaudhary LN; Froedtert & Medical College of Wisconsin, Cancer Center, Milwaukee, WI, 53226., Burkard ME; UI Holden Comprehensive Cancer Center, Iowa City, IA 52242., Giever T; Froedtert & Medical College of Wisconsin, Cancer Center, Milwaukee, WI, 53226., Cheng YC; Froedtert & Medical College of Wisconsin, Cancer Center, Milwaukee, WI, 53226., Parkes A; Department of Hematology-Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792., Lange CA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455., Pipp-Dahm M; Department of Hematology-Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792., Hegeman R; Division of Hematology-Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53715-2052., Siddiqui N; Division of Hematology-Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53715-2052., Stella A; Division of Hematology-Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53718., Rajguru S; Division of Hematology-Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53713-1997., Twaroski K; UW Carbone Cancer Center, Madison, WI 53792., Zurbriggen L; Hematology, Medical Oncology and Palliative Care, Clinical Science Center, University of Wisconsin School of Medicine and Public Health, Madison WI 53792-0001., Jorns JM; Froedtert & Medical College of Wisconsin, Cancer Center, Milwaukee, WI, 53226; Pathology, Froedtert & Medical College of Wisconsin, Milwaukee, WI 53226., Rui H; Thomas Jefferson University, Philadelphia, PA 19107., Keigley QJ; Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI 53792-3252., Perlman SB; Radiology, Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792-3252., Salem K; Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792., Bradshaw TJ; University of Wisconsin School of Medicine and Public Health, Madison, WI 53792., Sahmoud T; Oncology Drug Development, New Hope, Pennsylvania, PA., Wisinski K; Medical Oncology and Palliative Care, Department of Medicine, Breast Cancer Disease Oriented Team, University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792-3252.
Source: Clinical breast cancer [Clin Breast Cancer] 2025 Apr; Vol. 25 (3), pp. 251-260. Date of Electronic Publication: 2024 Dec 10.
Publication Type: Journal Article; Clinical Trial, Phase II; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 100898731 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-0666 (Electronic) Linking ISSN: 15268209 NLM ISO Abbreviation: Clin Breast Cancer Subsets: MEDLINE
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  Data: A Phase II Trial of Onapristone and Fulvestrant for Patients With ER+ and HER2- Metastatic Breast Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Kamaraju+S%22">Kamaraju S</searchLink>; Froedtert & Medical College of Wisconsin, Cancer Center, Milwaukee, WI, 53226. Electronic address: skamaraju@mcw.edu.<br /><searchLink fieldCode="AU" term="%22Fowler+AM%22">Fowler AM</searchLink>; Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI 53792-3252.<br /><searchLink fieldCode="AU" term="%22Tarima+S%22">Tarima S</searchLink>; Froedtert & Medical College of Wisconsin, Cancer Center, Milwaukee, WI, 53226; Department of Biostatistics, Medical College of Wisconsin, Milwaukee, WI 53226.<br /><searchLink fieldCode="AU" term="%22Chaudhary+LN%22">Chaudhary LN</searchLink>; Froedtert & Medical College of Wisconsin, Cancer Center, Milwaukee, WI, 53226.<br /><searchLink fieldCode="AU" term="%22Burkard+ME%22">Burkard ME</searchLink>; UI Holden Comprehensive Cancer Center, Iowa City, IA 52242.<br /><searchLink fieldCode="AU" term="%22Giever+T%22">Giever T</searchLink>; Froedtert & Medical College of Wisconsin, Cancer Center, Milwaukee, WI, 53226.<br /><searchLink fieldCode="AU" term="%22Cheng+YC%22">Cheng YC</searchLink>; Froedtert & Medical College of Wisconsin, Cancer Center, Milwaukee, WI, 53226.<br /><searchLink fieldCode="AU" term="%22Parkes+A%22">Parkes A</searchLink>; Department of Hematology-Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792.<br /><searchLink fieldCode="AU" term="%22Lange+CA%22">Lange CA</searchLink>; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455.<br /><searchLink fieldCode="AU" term="%22Pipp-Dahm+M%22">Pipp-Dahm M</searchLink>; Department of Hematology-Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792.<br /><searchLink fieldCode="AU" term="%22Hegeman+R%22">Hegeman R</searchLink>; Division of Hematology-Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53715-2052.<br /><searchLink fieldCode="AU" term="%22Siddiqui+N%22">Siddiqui N</searchLink>; Division of Hematology-Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53715-2052.<br /><searchLink fieldCode="AU" term="%22Stella+A%22">Stella A</searchLink>; Division of Hematology-Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53718.<br /><searchLink fieldCode="AU" term="%22Rajguru+S%22">Rajguru S</searchLink>; Division of Hematology-Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53713-1997.<br /><searchLink fieldCode="AU" term="%22Twaroski+K%22">Twaroski K</searchLink>; UW Carbone Cancer Center, Madison, WI 53792.<br /><searchLink fieldCode="AU" term="%22Zurbriggen+L%22">Zurbriggen L</searchLink>; Hematology, Medical Oncology and Palliative Care, Clinical Science Center, University of Wisconsin School of Medicine and Public Health, Madison WI 53792-0001.<br /><searchLink fieldCode="AU" term="%22Jorns+JM%22">Jorns JM</searchLink>; Froedtert & Medical College of Wisconsin, Cancer Center, Milwaukee, WI, 53226; Pathology, Froedtert & Medical College of Wisconsin, Milwaukee, WI 53226.<br /><searchLink fieldCode="AU" term="%22Rui+H%22">Rui H</searchLink>; Thomas Jefferson University, Philadelphia, PA 19107.<br /><searchLink fieldCode="AU" term="%22Keigley+QJ%22">Keigley QJ</searchLink>; Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI 53792-3252.<br /><searchLink fieldCode="AU" term="%22Perlman+SB%22">Perlman SB</searchLink>; Radiology, Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792-3252.<br /><searchLink fieldCode="AU" term="%22Salem+K%22">Salem K</searchLink>; Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792.<br /><searchLink fieldCode="AU" term="%22Bradshaw+TJ%22">Bradshaw TJ</searchLink>; University of Wisconsin School of Medicine and Public Health, Madison, WI 53792.<br /><searchLink fieldCode="AU" term="%22Sahmoud+T%22">Sahmoud T</searchLink>; Oncology Drug Development, New Hope, Pennsylvania, PA.<br /><searchLink fieldCode="AU" term="%22Wisinski+K%22">Wisinski K</searchLink>; Medical Oncology and Palliative Care, Department of Medicine, Breast Cancer Disease Oriented Team, University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792-3252.
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  Data: <searchLink fieldCode="JN" term="%22100898731%22">Clinical breast cancer</searchLink> [Clin Breast Cancer] 2025 Apr; Vol. 25 (3), pp. 251-260. <i>Date of Electronic Publication: </i>2024 Dec 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100898731 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1938-0666 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215268209%22">15268209 </searchLink><i>NLM ISO Abbreviation: </i>Clin Breast Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.clbc.2024.11.019
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