Comparative analysis of empty and full adeno-associated viruses under stress conditions by anion-exchange chromatography, analytical ultracentrifugation, and mass photometry.
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| Title: | Comparative analysis of empty and full adeno-associated viruses under stress conditions by anion-exchange chromatography, analytical ultracentrifugation, and mass photometry. |
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| Authors: | Townsend JA; Analytical Chemistry, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA., Li S; Formulation Development, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA., Sweezy L; Protein Biochemistry, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA., Liu N; Protein Biochemistry, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA., Rosconi MP; Protein Biochemistry, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA., Pyles EA; Protein Biochemistry, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA., Zhi L; Formulation Development, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA., Liu D; Formulation Development, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA., Wu Z; Analytical Chemistry, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA. Electronic address: zhijie.wu@regeneron.com., Qiu H; Analytical Chemistry, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA. Electronic address: haibo.qiu@regeneron.com., Shameem M; Formulation Development, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA., Li N; Analytical Chemistry, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA. |
| Source: | Journal of pharmaceutical sciences [J Pharm Sci] 2025 Feb; Vol. 114 (2), pp. 1237-1244. Date of Electronic Publication: 2025 Jan 17. |
| Publication Type: | Journal Article; Comparative Study |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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