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Assessing the efficacy of iso-mukaadial acetate and betulinic acid against selected Plasmodium falciparum glycolytic pathway proteins: in silico and in vitro studies.

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Title: Assessing the efficacy of iso-mukaadial acetate and betulinic acid against selected Plasmodium falciparum glycolytic pathway proteins: in silico and in vitro studies.
Authors: Zuma LK; Discipline of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban, 4000, South Africa., Pooe OJ; Discipline of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban, 4000, South Africa. pooeo@ukzn.ac.za., Mabaso NH; Discipline of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban, 4000, South Africa., Alake J; Department of Pharmaceutical Chemistry, Discipline of Pharmaceutical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, 4000, South Africa., Obakachi VA; Department of Pharmaceutical Chemistry, Discipline of Pharmaceutical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, 4000, South Africa., Yakobi S; Discipline of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban, 4000, South Africa., Gasa N; Discipline of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban, 4000, South Africa., Karpoormath R; Department of Pharmaceutical Chemistry, Discipline of Pharmaceutical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, 4000, South Africa., Simelane M; Department of Biochemistry, University of Johannesburg, Auckland Park Campus, Cnr Kingsway Avenue and University Road, Auckland, Park, PO Box 524, Johannesburg, 2006, South Africa.
Source: BMC chemistry [BMC Chem] 2025 Jan 18; Vol. 19 (1), pp. 16. Date of Electronic Publication: 2025 Jan 18.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: Switzerland NLM ID: 101741142 Publication Model: Electronic Cited Medium: Internet ISSN: 2661-801X (Electronic) Linking ISSN: 2661801X NLM ISO Abbreviation: BMC Chem Subsets: PubMed not MEDLINE
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  Data: Assessing the efficacy of iso-mukaadial acetate and betulinic acid against selected Plasmodium falciparum glycolytic pathway proteins: in silico and in vitro studies.
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  Data: <searchLink fieldCode="AU" term="%22Zuma+LK%22">Zuma LK</searchLink>; Discipline of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban, 4000, South Africa.<br /><searchLink fieldCode="AU" term="%22Pooe+OJ%22">Pooe OJ</searchLink>; Discipline of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban, 4000, South Africa. pooeo@ukzn.ac.za.<br /><searchLink fieldCode="AU" term="%22Mabaso+NH%22">Mabaso NH</searchLink>; Discipline of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban, 4000, South Africa.<br /><searchLink fieldCode="AU" term="%22Alake+J%22">Alake J</searchLink>; Department of Pharmaceutical Chemistry, Discipline of Pharmaceutical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, 4000, South Africa.<br /><searchLink fieldCode="AU" term="%22Obakachi+VA%22">Obakachi VA</searchLink>; Department of Pharmaceutical Chemistry, Discipline of Pharmaceutical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, 4000, South Africa.<br /><searchLink fieldCode="AU" term="%22Yakobi+S%22">Yakobi S</searchLink>; Discipline of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban, 4000, South Africa.<br /><searchLink fieldCode="AU" term="%22Gasa+N%22">Gasa N</searchLink>; Discipline of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban, 4000, South Africa.<br /><searchLink fieldCode="AU" term="%22Karpoormath+R%22">Karpoormath R</searchLink>; Department of Pharmaceutical Chemistry, Discipline of Pharmaceutical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, 4000, South Africa.<br /><searchLink fieldCode="AU" term="%22Simelane+M%22">Simelane M</searchLink>; Department of Biochemistry, University of Johannesburg, Auckland Park Campus, Cnr Kingsway Avenue and University Road, Auckland, Park, PO Box 524, Johannesburg, 2006, South Africa.
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  Data: <searchLink fieldCode="JN" term="%22101741142%22">BMC chemistry</searchLink> [BMC Chem] 2025 Jan 18; Vol. 19 (1), pp. 16. <i>Date of Electronic Publication: </i>2025 Jan 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101741142 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2661-801X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222661801X%22">2661801X </searchLink><i>NLM ISO Abbreviation: </i>BMC Chem <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2025 Jan 18
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