View in EDS HTML Full Text PDF Full Text

Preliminary effects of oral ANS-6637, an ALDH2 inhibitor, on cue-induced craving, safety and alcohol consumption among adults with alcohol use disorder: a proof-of-concept, randomized, human laboratory trial.

Saved in:
Bibliographic Details
Title: Preliminary effects of oral ANS-6637, an ALDH2 inhibitor, on cue-induced craving, safety and alcohol consumption among adults with alcohol use disorder: a proof-of-concept, randomized, human laboratory trial.
Authors: O'Malley SS; Department of Psychiatry, Yale School of Medicine, 34 Park Street, New Haven, CT 06519, United States., Miranda R Jr; Department of Psychiatry and Human Behavior, Brown University, 121 S. Main Street, Providence, RI 02912, United States., Book SW; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, United States., Chun TH; Departments of Emergency Medicine and Pediatrics, Alpert Medical School of Brown University, Rhode Island Hospital, Claverick 2, 593 Eddy Street, Providence, RI 02903, United States., Liss T; Department of Psychiatry, Yale School of Medicine, 34 Park Street, New Haven, CT 06519, United States., Malcolm RJ; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, United States., Muvvala SB; Department of Psychiatry, Yale School of Medicine, 34 Park Street, New Haven, CT 06519, United States., Padovano HT; Department of Psychiatry and Human Behavior, Brown University, 121 S. Main Street, Providence, RI 02912, United States., Schacht JP; Department of Psychiatry, University of Colorado School of Medicine, 1890 N. Revere Court, Mail Stop F570, Aurora, CO 80045, United States., Blackburn B; Amygdala Neurosciences, Inc., 5214F Diamond Heights Blvd #151, San Francisco, CA 94131, United States., Diamond I; Amygdala Neurosciences, Inc., 5214F Diamond Heights Blvd #151, San Francisco, CA 94131, United States., Ransom J; Fast-Track Drugs & Biologics, LLC, 20010 Fisher Avenue, Suite G, Poolesville, MD 20837, United States., Ryan ML; Division of Treatment and Recovery, National Institute on Alcohol Abuse and Alcoholism, 6700 B Rockledge Drive, Bethesda, MD 20892, United States., Falk DE; Division of Treatment and Recovery, National Institute on Alcohol Abuse and Alcoholism, 6700 B Rockledge Drive, Bethesda, MD 20892, United States., Litten RZ; Division of Treatment and Recovery, National Institute on Alcohol Abuse and Alcoholism, 6700 B Rockledge Drive, Bethesda, MD 20892, United States.
Source: Alcohol and alcoholism (Oxford, Oxfordshire) [Alcohol Alcohol] 2025 Jan 19; Vol. 60 (2).
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8310684 Publication Model: Print Cited Medium: Internet ISSN: 1464-3502 (Electronic) Linking ISSN: 07350414 NLM ISO Abbreviation: Alcohol Alcohol Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 39829301
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Preliminary effects of oral ANS-6637, an ALDH2 inhibitor, on cue-induced craving, safety and alcohol consumption among adults with alcohol use disorder: a proof-of-concept, randomized, human laboratory trial.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22O'Malley+SS%22">O'Malley SS</searchLink>; Department of Psychiatry, Yale School of Medicine, 34 Park Street, New Haven, CT 06519, United States.<br /><searchLink fieldCode="AU" term="%22Miranda+R+Jr%22">Miranda R Jr</searchLink>; Department of Psychiatry and Human Behavior, Brown University, 121 S. Main Street, Providence, RI 02912, United States.<br /><searchLink fieldCode="AU" term="%22Book+SW%22">Book SW</searchLink>; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, United States.<br /><searchLink fieldCode="AU" term="%22Chun+TH%22">Chun TH</searchLink>; Departments of Emergency Medicine and Pediatrics, Alpert Medical School of Brown University, Rhode Island Hospital, Claverick 2, 593 Eddy Street, Providence, RI 02903, United States.<br /><searchLink fieldCode="AU" term="%22Liss+T%22">Liss T</searchLink>; Department of Psychiatry, Yale School of Medicine, 34 Park Street, New Haven, CT 06519, United States.<br /><searchLink fieldCode="AU" term="%22Malcolm+RJ%22">Malcolm RJ</searchLink>; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, United States.<br /><searchLink fieldCode="AU" term="%22Muvvala+SB%22">Muvvala SB</searchLink>; Department of Psychiatry, Yale School of Medicine, 34 Park Street, New Haven, CT 06519, United States.<br /><searchLink fieldCode="AU" term="%22Padovano+HT%22">Padovano HT</searchLink>; Department of Psychiatry and Human Behavior, Brown University, 121 S. Main Street, Providence, RI 02912, United States.<br /><searchLink fieldCode="AU" term="%22Schacht+JP%22">Schacht JP</searchLink>; Department of Psychiatry, University of Colorado School of Medicine, 1890 N. Revere Court, Mail Stop F570, Aurora, CO 80045, United States.<br /><searchLink fieldCode="AU" term="%22Blackburn+B%22">Blackburn B</searchLink>; Amygdala Neurosciences, Inc., 5214F Diamond Heights Blvd #151, San Francisco, CA 94131, United States.<br /><searchLink fieldCode="AU" term="%22Diamond+I%22">Diamond I</searchLink>; Amygdala Neurosciences, Inc., 5214F Diamond Heights Blvd #151, San Francisco, CA 94131, United States.<br /><searchLink fieldCode="AU" term="%22Ransom+J%22">Ransom J</searchLink>; Fast-Track Drugs & Biologics, LLC, 20010 Fisher Avenue, Suite G, Poolesville, MD 20837, United States.<br /><searchLink fieldCode="AU" term="%22Ryan+ML%22">Ryan ML</searchLink>; Division of Treatment and Recovery, National Institute on Alcohol Abuse and Alcoholism, 6700 B Rockledge Drive, Bethesda, MD 20892, United States.<br /><searchLink fieldCode="AU" term="%22Falk+DE%22">Falk DE</searchLink>; Division of Treatment and Recovery, National Institute on Alcohol Abuse and Alcoholism, 6700 B Rockledge Drive, Bethesda, MD 20892, United States.<br /><searchLink fieldCode="AU" term="%22Litten+RZ%22">Litten RZ</searchLink>; Division of Treatment and Recovery, National Institute on Alcohol Abuse and Alcoholism, 6700 B Rockledge Drive, Bethesda, MD 20892, United States.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%228310684%22">Alcohol and alcoholism (Oxford, Oxfordshire)</searchLink> [Alcohol Alcohol] 2025 Jan 19; Vol. 60 (2).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Randomized Controlled Trial; Multicenter Study
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8310684 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1464-3502 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207350414%22">07350414 </searchLink><i>NLM ISO Abbreviation: </i>Alcohol Alcohol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39829301
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1093/alcalc/agaf001
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Preliminary effects of oral ANS-6637, an ALDH2 inhibitor, on cue-induced craving, safety and alcohol consumption among adults with alcohol use disorder: a proof-of-concept, randomized, human laboratory trial.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: O'Malley SS
      – PersonEntity:
          Name:
            NameFull: Miranda R Jr
      – PersonEntity:
          Name:
            NameFull: Book SW
      – PersonEntity:
          Name:
            NameFull: Chun TH
      – PersonEntity:
          Name:
            NameFull: Liss T
      – PersonEntity:
          Name:
            NameFull: Malcolm RJ
      – PersonEntity:
          Name:
            NameFull: Muvvala SB
      – PersonEntity:
          Name:
            NameFull: Padovano HT
      – PersonEntity:
          Name:
            NameFull: Schacht JP
      – PersonEntity:
          Name:
            NameFull: Blackburn B
      – PersonEntity:
          Name:
            NameFull: Diamond I
      – PersonEntity:
          Name:
            NameFull: Ransom J
      – PersonEntity:
          Name:
            NameFull: Ryan ML
      – PersonEntity:
          Name:
            NameFull: Falk DE
      – PersonEntity:
          Name:
            NameFull: Litten RZ
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 19
              M: 01
              Text: 2025 Jan 19
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1464-3502
          Numbering:
            – Type: volume
              Value: 60
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Alcohol and alcoholism (Oxford, Oxfordshire)
              Type: main
ResultId 1