A randomised double-blind, placebo-controlled trial of pramipexole in addition to mood stabilisers for patients with treatment-resistant bipolar depression (the PAX-BD study).

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Title: A randomised double-blind, placebo-controlled trial of pramipexole in addition to mood stabilisers for patients with treatment-resistant bipolar depression (the PAX-BD study).
Authors: McAllister-Williams RH; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Northern Centre for Mood Disorders, Newcastle University, Newcastle upon Tyne, UK.; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK., Goudie N; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Azim L; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK., Bartle V; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK., Berger M; Department of Health Economics, Center for Public Health, Medical University of Vienna, Vienna, Austria., Butcher C; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Chadwick T; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Clare E; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK., Courtney P; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK., Dixon L; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK., Duffelen N; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK., Fouweather T; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Gann W; Sheffield Health and Social Care NHS Foundation Trust, Sheffield, UK., Geddes J; Department of Psychiatry, University of Oxford, Oxford, UK., Gupta S; Tees, Esk and Wear Valleys NHS Foundation Trust, Darlington, UK., Hall B; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK., Helter T; Department of Health Economics, Center for Public Health, Medical University of Vienna, Vienna, Austria., Hindmarch P; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK., Holstein EM; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Lawrence W; Surrey and Borders Partnership NHS Trust, Leatherhead, UK., Mawson P; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., McKinnon I; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Milne A; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Molloy A; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK., Moore A; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Morriss R; Academic Unit of Mental Health and Neuroscience, University of Nottingham, Nottingham, UK., Nakulan A; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK., Simon J; Department of Health Economics, Center for Public Health, Medical University of Vienna, Vienna, Austria.; Department of Psychiatry, University of Oxford, Oxford, UK., Smith D; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK., Stokes-Crossley B; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK., Stokes PR; Department of Psychological Medicine, Centre for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Swain A; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Taiwo A; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK., Walmsley Z; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Weetman C; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Young AH; Department of Psychological Medicine, Centre for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Watson S; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Northern Centre for Mood Disorders, Newcastle University, Newcastle upon Tyne, UK.; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.
Source: Journal of psychopharmacology (Oxford, England) [J Psychopharmacol] 2025 Feb; Vol. 39 (2), pp. 106-120. Date of Electronic Publication: 2025 Jan 20.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 8907828 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1461-7285 (Electronic) Linking ISSN: 02698811 NLM ISO Abbreviation: J Psychopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A randomised double-blind, placebo-controlled trial of pramipexole in addition to mood stabilisers for patients with treatment-resistant bipolar depression (the PAX-BD study).
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  Data: <searchLink fieldCode="AU" term="%22McAllister-Williams+RH%22">McAllister-Williams RH</searchLink>; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Northern Centre for Mood Disorders, Newcastle University, Newcastle upon Tyne, UK.; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Goudie+N%22">Goudie N</searchLink>; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Azim+L%22">Azim L</searchLink>; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Bartle+V%22">Bartle V</searchLink>; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Berger+M%22">Berger M</searchLink>; Department of Health Economics, Center for Public Health, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Butcher+C%22">Butcher C</searchLink>; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Chadwick+T%22">Chadwick T</searchLink>; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Clare+E%22">Clare E</searchLink>; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Courtney+P%22">Courtney P</searchLink>; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Dixon+L%22">Dixon L</searchLink>; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Duffelen+N%22">Duffelen N</searchLink>; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Fouweather+T%22">Fouweather T</searchLink>; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Gann+W%22">Gann W</searchLink>; Sheffield Health and Social Care NHS Foundation Trust, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Geddes+J%22">Geddes J</searchLink>; Department of Psychiatry, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Gupta+S%22">Gupta S</searchLink>; Tees, Esk and Wear Valleys NHS Foundation Trust, Darlington, UK.<br /><searchLink fieldCode="AU" term="%22Hall+B%22">Hall B</searchLink>; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Helter+T%22">Helter T</searchLink>; Department of Health Economics, Center for Public Health, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hindmarch+P%22">Hindmarch P</searchLink>; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Holstein+EM%22">Holstein EM</searchLink>; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Lawrence+W%22">Lawrence W</searchLink>; Surrey and Borders Partnership NHS Trust, Leatherhead, UK.<br /><searchLink fieldCode="AU" term="%22Mawson+P%22">Mawson P</searchLink>; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22McKinnon+I%22">McKinnon I</searchLink>; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Milne+A%22">Milne A</searchLink>; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Molloy+A%22">Molloy A</searchLink>; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Moore+A%22">Moore A</searchLink>; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Morriss+R%22">Morriss R</searchLink>; Academic Unit of Mental Health and Neuroscience, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Nakulan+A%22">Nakulan A</searchLink>; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Simon+J%22">Simon J</searchLink>; Department of Health Economics, Center for Public Health, Medical University of Vienna, Vienna, Austria.; Department of Psychiatry, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Smith+D%22">Smith D</searchLink>; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Stokes-Crossley+B%22">Stokes-Crossley B</searchLink>; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Stokes+PR%22">Stokes PR</searchLink>; Department of Psychological Medicine, Centre for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Swain+A%22">Swain A</searchLink>; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Taiwo+A%22">Taiwo A</searchLink>; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Walmsley+Z%22">Walmsley Z</searchLink>; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Weetman+C%22">Weetman C</searchLink>; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Young+AH%22">Young AH</searchLink>; Department of Psychological Medicine, Centre for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Watson+S%22">Watson S</searchLink>; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Northern Centre for Mood Disorders, Newcastle University, Newcastle upon Tyne, UK.; Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.
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  Data: <searchLink fieldCode="JN" term="%228907828%22">Journal of psychopharmacology (Oxford, England)</searchLink> [J Psychopharmacol] 2025 Feb; Vol. 39 (2), pp. 106-120. <i>Date of Electronic Publication: </i>2025 Jan 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Sage+Publications%22">Sage Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8907828 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1461-7285 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202698811%22">02698811 </searchLink><i>NLM ISO Abbreviation: </i>J Psychopharmacol <i>Subsets: </i>MEDLINE
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