Discovery of 2-Pyrazolines That Inhibit the Phosphorylation of STAT3 as Nanomolar Cytotoxic Agents.

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Title: Discovery of 2-Pyrazolines That Inhibit the Phosphorylation of STAT3 as Nanomolar Cytotoxic Agents.
Authors: Siddappa TP; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka 570006, India., Ravish A; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka 570006, India., Xi Z; Shenzhen Bay Laboratory, Shenzhen 518055, China., Mohan A; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka 570006, India., Girimanchanaika SS; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka 570006, India., Krishnamurthy NP; NMR Research Centre, Indian Institute of Science, Bangalore, Karnataka 560012, India., Basappa S; Department of Chemistry, BITS-Pilani Hyderabad Campus, Jawahar Nagar, Medchal 500078, India., Gaonkar SL; Department of Chemistry, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, Karnataka 576104, India., Lobie PE; Shenzhen Bay Laboratory, Shenzhen 518055, China.; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China., Pandey V; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China., Basappa B; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka 570006, India.
Source: ACS omega [ACS Omega] 2025 Jan 02; Vol. 10 (1), pp. 114-126. Date of Electronic Publication: 2025 Jan 02 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101691658 Publication Model: eCollection Cited Medium: Internet ISSN: 2470-1343 (Electronic) Linking ISSN: 24701343 NLM ISO Abbreviation: ACS Omega Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2470-1343
DOI:10.1021/acsomega.3c10504