Oral vs Intravenous Antibiotics for Fracture-Related Infections: The POvIV Randomized Clinical Trial.
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| Title: | Oral vs Intravenous Antibiotics for Fracture-Related Infections: The POvIV Randomized Clinical Trial. |
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| Authors: | Obremskey WT; Vanderbilt University Medical Center, Nashville, Tennessee., O'Toole RV; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore., Morshed S; The University of California, San Francisco., Tornetta P 3rd; Boston Medical Center, Boston, Massachusetts., Murray CK; Brooke Army Medical Center, Fort Sam Houston, Texas., Jones CB; Center for Orthopedic Research and Education, Phoenix, Arizona.; Now with Dignity Health, Creighton Medical Phoenix, Phoenix, Arizona., Scharfstein DO; Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Taylor TJ; Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Carlini AR; Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., DeSanto JM; Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Castillo RC; Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Bosse MJ; Atrium Health Carolinas Medical Center, Charlotte, North Carolina., Karunakar MA; Atrium Health Carolinas Medical Center, Charlotte, North Carolina., Seymour RB; Atrium Health Carolinas Medical Center, Charlotte, North Carolina., Sims SH; Atrium Health Carolinas Medical Center, Charlotte, North Carolina., Weinrib DA; Atrium Health Carolinas Medical Center, Charlotte, North Carolina., Churchill C; Atrium Health Carolinas Medical Center, Charlotte, North Carolina., Carroll EA; Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, North Carolina., Pilson HT; Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, North Carolina., Goodman JB; Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, North Carolina., Holden MB; Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, North Carolina., Miller AN; Barnes-Jewish Hospital at Washington University in St Louis, St Louis, Missouri., Sietsema DL; Center for Orthopedic Research and Education, Phoenix, Arizona., Stahel PF; Denver Health and Hospital Authority, Denver, Colorado., Mir H; Florida Orthopaedic Institute, Tampa., Schmidt AH; Hennepin Healthcare, Minneapolis, Minnesota., Westberg JR; Hennepin Healthcare, Minneapolis, Minnesota., Mullis B; Eskenazi Health, Indiana University, Indianapolis, Indiana., Shively KD; Eskenazi Health, Indiana University, Indianapolis, Indiana., Hymes RA; Inova Fairfax Medical Campus, Annandale, Virginia., Konda SR; Jamaica Hospital Medical Center, Queens, New York., Vallier HA; MetroHealth Medical Center, Cleveland, Ohio., Breslin MA; MetroHealth Medical Center, Cleveland, Ohio., Smith CS; Naval Medical Center Portsmouth, Portsmouth, Virginia., Crickard CV; Naval Medical Center Portsmouth, Portsmouth, Virginia., Egol KA; New York University, New York., Reid JS; Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania., Baker M; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore., Eglseder WA; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore., LeBrun C; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore., Manson T; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore., Mascarenhas DC; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore., Nascone J; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore., Pollak AN; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore., Schloss MG; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore., Sciadini MF; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore., Degani Y; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore., Miclau T; The University of California, San Francisco., Weiss DB; University of Virginia Health, Charlottesville., Yarboro SR; University of Virginia Health, Charlottesville., McVey ED; University of Virginia Health, Charlottesville., Firoozabadi R; University of Washington Medicine Harborview Medical Center, Seattle., Agel J; University of Washington Medicine Harborview Medical Center, Seattle., Whiting PS; University of Wisconsin, Madison., Haleem A; University of Wisconsin, Madison., Domes C; University of Wisconsin, Madison., Lang GJ; University of Wisconsin, Madison., Kuhn GR; University of Wisconsin, Madison., Archer KR; Vanderbilt University Medical Center, Nashville, Tennessee., Talbot T; Vanderbilt University Medical Center, Nashville, Tennessee., Burgos EJ; Vanderbilt University Medical Center, Nashville, Tennessee., Gajari V; Vanderbilt University Medical Center, Nashville, Tennessee., Herrera LN; Vanderbilt University Medical Center, Nashville, Tennessee., Rodriguez-Buitrago A; Vanderbilt University Medical Center, Nashville, Tennessee., Tummuru RR; Vanderbilt University Medical Center, Nashville, Tennessee., Abraham CM; Vanderbilt University Medical Center, Nashville, Tennessee.; Now with Good Shepherd Rehabilitation Network, Center Valley, Pennsylvania., Trochez KM; Vanderbilt University Medical Center, Nashville, Tennessee. |
| Corporate Authors: | Major Extremity Trauma Research Consortium (METRC) |
| Source: | JAMA surgery [JAMA Surg] 2025 Mar 01; Vol. 160 (3), pp. 276-284. |
| Publication Type: | Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial |
| Journal Info: | Publisher: American Medical Association Country of Publication: United States NLM ID: 101589553 Publication Model: Print Cited Medium: Internet ISSN: 2168-6262 (Electronic) Linking ISSN: 21686254 NLM ISO Abbreviation: JAMA Surg Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39841468 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Oral vs Intravenous Antibiotics for Fracture-Related Infections: The POvIV Randomized Clinical Trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Obremskey+WT%22">Obremskey WT</searchLink>; Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22O'Toole+RV%22">O'Toole RV</searchLink>; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore.<br /><searchLink fieldCode="AU" term="%22Morshed+S%22">Morshed S</searchLink>; The University of California, San Francisco.<br /><searchLink fieldCode="AU" term="%22Tornetta+P+3rd%22">Tornetta P 3rd</searchLink>; Boston Medical Center, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Murray+CK%22">Murray CK</searchLink>; Brooke Army Medical Center, Fort Sam Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Jones+CB%22">Jones CB</searchLink>; Center for Orthopedic Research and Education, Phoenix, Arizona.; Now with Dignity Health, Creighton Medical Phoenix, Phoenix, Arizona.<br /><searchLink fieldCode="AU" term="%22Scharfstein+DO%22">Scharfstein DO</searchLink>; Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Taylor+TJ%22">Taylor TJ</searchLink>; Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Carlini+AR%22">Carlini AR</searchLink>; Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22DeSanto+JM%22">DeSanto JM</searchLink>; Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Castillo+RC%22">Castillo RC</searchLink>; Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Bosse+MJ%22">Bosse MJ</searchLink>; Atrium Health Carolinas Medical Center, Charlotte, North Carolina.<br /><searchLink fieldCode="AU" term="%22Karunakar+MA%22">Karunakar MA</searchLink>; Atrium Health Carolinas Medical Center, Charlotte, North Carolina.<br /><searchLink fieldCode="AU" term="%22Seymour+RB%22">Seymour RB</searchLink>; Atrium Health Carolinas Medical Center, Charlotte, North Carolina.<br /><searchLink fieldCode="AU" term="%22Sims+SH%22">Sims SH</searchLink>; Atrium Health Carolinas Medical Center, Charlotte, North Carolina.<br /><searchLink fieldCode="AU" term="%22Weinrib+DA%22">Weinrib DA</searchLink>; Atrium Health Carolinas Medical Center, Charlotte, North Carolina.<br /><searchLink fieldCode="AU" term="%22Churchill+C%22">Churchill C</searchLink>; Atrium Health Carolinas Medical Center, Charlotte, North Carolina.<br /><searchLink fieldCode="AU" term="%22Carroll+EA%22">Carroll EA</searchLink>; Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Pilson+HT%22">Pilson HT</searchLink>; Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Goodman+JB%22">Goodman JB</searchLink>; Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Holden+MB%22">Holden MB</searchLink>; Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Miller+AN%22">Miller AN</searchLink>; Barnes-Jewish Hospital at Washington University in St Louis, St Louis, Missouri.<br /><searchLink fieldCode="AU" term="%22Sietsema+DL%22">Sietsema DL</searchLink>; Center for Orthopedic Research and Education, Phoenix, Arizona.<br /><searchLink fieldCode="AU" term="%22Stahel+PF%22">Stahel PF</searchLink>; Denver Health and Hospital Authority, Denver, Colorado.<br /><searchLink fieldCode="AU" term="%22Mir+H%22">Mir H</searchLink>; Florida Orthopaedic Institute, Tampa.<br /><searchLink fieldCode="AU" term="%22Schmidt+AH%22">Schmidt AH</searchLink>; Hennepin Healthcare, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Westberg+JR%22">Westberg JR</searchLink>; Hennepin Healthcare, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Mullis+B%22">Mullis B</searchLink>; Eskenazi Health, Indiana University, Indianapolis, Indiana.<br /><searchLink fieldCode="AU" term="%22Shively+KD%22">Shively KD</searchLink>; Eskenazi Health, Indiana University, Indianapolis, Indiana.<br /><searchLink fieldCode="AU" term="%22Hymes+RA%22">Hymes RA</searchLink>; Inova Fairfax Medical Campus, Annandale, Virginia.<br /><searchLink fieldCode="AU" term="%22Konda+SR%22">Konda SR</searchLink>; Jamaica Hospital Medical Center, Queens, New York.<br /><searchLink fieldCode="AU" term="%22Vallier+HA%22">Vallier HA</searchLink>; MetroHealth Medical Center, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Breslin+MA%22">Breslin MA</searchLink>; MetroHealth Medical Center, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Smith+CS%22">Smith CS</searchLink>; Naval Medical Center Portsmouth, Portsmouth, Virginia.<br /><searchLink fieldCode="AU" term="%22Crickard+CV%22">Crickard CV</searchLink>; Naval Medical Center Portsmouth, Portsmouth, Virginia.<br /><searchLink fieldCode="AU" term="%22Egol+KA%22">Egol KA</searchLink>; New York University, New York.<br /><searchLink fieldCode="AU" term="%22Reid+JS%22">Reid JS</searchLink>; Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Baker+M%22">Baker M</searchLink>; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore.<br /><searchLink fieldCode="AU" term="%22Eglseder+WA%22">Eglseder WA</searchLink>; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore.<br /><searchLink fieldCode="AU" term="%22LeBrun+C%22">LeBrun C</searchLink>; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore.<br /><searchLink fieldCode="AU" term="%22Manson+T%22">Manson T</searchLink>; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore.<br /><searchLink fieldCode="AU" term="%22Mascarenhas+DC%22">Mascarenhas DC</searchLink>; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore.<br /><searchLink fieldCode="AU" term="%22Nascone+J%22">Nascone J</searchLink>; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore.<br /><searchLink fieldCode="AU" term="%22Pollak+AN%22">Pollak AN</searchLink>; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore.<br /><searchLink fieldCode="AU" term="%22Schloss+MG%22">Schloss MG</searchLink>; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore.<br /><searchLink fieldCode="AU" term="%22Sciadini+MF%22">Sciadini MF</searchLink>; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore.<br /><searchLink fieldCode="AU" term="%22Degani+Y%22">Degani Y</searchLink>; R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine, Baltimore.<br /><searchLink fieldCode="AU" term="%22Miclau+T%22">Miclau T</searchLink>; The University of California, San Francisco.<br /><searchLink fieldCode="AU" term="%22Weiss+DB%22">Weiss DB</searchLink>; University of Virginia Health, Charlottesville.<br /><searchLink fieldCode="AU" term="%22Yarboro+SR%22">Yarboro SR</searchLink>; University of Virginia Health, Charlottesville.<br /><searchLink fieldCode="AU" term="%22McVey+ED%22">McVey ED</searchLink>; University of Virginia Health, Charlottesville.<br /><searchLink fieldCode="AU" term="%22Firoozabadi+R%22">Firoozabadi R</searchLink>; University of Washington Medicine Harborview Medical Center, Seattle.<br /><searchLink fieldCode="AU" term="%22Agel+J%22">Agel J</searchLink>; University of Washington Medicine Harborview Medical Center, Seattle.<br /><searchLink fieldCode="AU" term="%22Whiting+PS%22">Whiting PS</searchLink>; University of Wisconsin, Madison.<br /><searchLink fieldCode="AU" term="%22Haleem+A%22">Haleem A</searchLink>; University of Wisconsin, Madison.<br /><searchLink fieldCode="AU" term="%22Domes+C%22">Domes C</searchLink>; University of Wisconsin, Madison.<br /><searchLink fieldCode="AU" term="%22Lang+GJ%22">Lang GJ</searchLink>; University of Wisconsin, Madison.<br /><searchLink fieldCode="AU" term="%22Kuhn+GR%22">Kuhn GR</searchLink>; University of Wisconsin, Madison.<br /><searchLink fieldCode="AU" term="%22Archer+KR%22">Archer KR</searchLink>; Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Talbot+T%22">Talbot T</searchLink>; Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Burgos+EJ%22">Burgos EJ</searchLink>; Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Gajari+V%22">Gajari V</searchLink>; Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Herrera+LN%22">Herrera LN</searchLink>; Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Buitrago+A%22">Rodriguez-Buitrago A</searchLink>; Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Tummuru+RR%22">Tummuru RR</searchLink>; Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Abraham+CM%22">Abraham CM</searchLink>; Vanderbilt University Medical Center, Nashville, Tennessee.; Now with Good Shepherd Rehabilitation Network, Center Valley, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Trochez+KM%22">Trochez KM</searchLink>; Vanderbilt University Medical Center, Nashville, Tennessee. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22Major+Extremity+Trauma+Research+Consortium+%28METRC%29%22">Major Extremity Trauma Research Consortium (METRC)</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101589553%22">JAMA surgery</searchLink> [JAMA Surg] 2025 Mar 01; Vol. 160 (3), pp. 276-284. – Name: TypePub Label: Publication Type Group: TypPub Data: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Medical+Association%22">American Medical Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101589553 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2168-6262 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221686254%22">21686254 </searchLink><i>NLM ISO Abbreviation: </i>JAMA Surg <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39841468 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1001/jamasurg.2024.6439 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 276 Titles: – TitleFull: Oral vs Intravenous Antibiotics for Fracture-Related Infections: The POvIV Randomized Clinical Trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Obremskey WT – PersonEntity: Name: NameFull: O'Toole RV – PersonEntity: Name: NameFull: Morshed S – PersonEntity: Name: NameFull: Tornetta P 3rd – PersonEntity: Name: NameFull: Murray CK – PersonEntity: Name: NameFull: Jones CB – PersonEntity: Name: NameFull: Scharfstein DO – PersonEntity: Name: NameFull: Taylor TJ – PersonEntity: Name: NameFull: Carlini AR – PersonEntity: Name: NameFull: DeSanto JM – PersonEntity: Name: NameFull: Castillo RC – PersonEntity: Name: NameFull: Bosse MJ – PersonEntity: Name: NameFull: Karunakar MA – PersonEntity: Name: NameFull: Seymour RB – PersonEntity: Name: NameFull: Sims SH – PersonEntity: Name: NameFull: Weinrib DA – PersonEntity: Name: NameFull: Churchill C – PersonEntity: Name: NameFull: Carroll EA – PersonEntity: Name: NameFull: Pilson HT – PersonEntity: Name: NameFull: Goodman JB – PersonEntity: Name: NameFull: Holden MB – PersonEntity: Name: NameFull: Miller AN – PersonEntity: Name: NameFull: Sietsema DL – PersonEntity: Name: NameFull: Stahel PF – PersonEntity: Name: NameFull: Mir H – PersonEntity: Name: NameFull: Schmidt AH – PersonEntity: Name: NameFull: Westberg JR – PersonEntity: Name: NameFull: Mullis B – PersonEntity: Name: NameFull: Shively KD – PersonEntity: Name: NameFull: Hymes RA – PersonEntity: Name: NameFull: Konda SR – PersonEntity: Name: NameFull: Vallier HA – PersonEntity: Name: NameFull: Breslin MA – PersonEntity: Name: NameFull: Smith CS – PersonEntity: Name: NameFull: Crickard CV – PersonEntity: Name: NameFull: Egol KA – PersonEntity: Name: NameFull: Reid JS – PersonEntity: Name: NameFull: Baker M – PersonEntity: Name: NameFull: Eglseder WA – PersonEntity: Name: NameFull: LeBrun C – PersonEntity: Name: NameFull: Manson T – PersonEntity: Name: NameFull: Mascarenhas DC – PersonEntity: Name: NameFull: Nascone J – PersonEntity: Name: NameFull: Pollak AN – PersonEntity: Name: NameFull: Schloss MG – PersonEntity: Name: NameFull: Sciadini MF – PersonEntity: Name: NameFull: Degani Y – PersonEntity: Name: NameFull: Miclau T – PersonEntity: Name: NameFull: Weiss DB – PersonEntity: Name: NameFull: Yarboro SR – PersonEntity: Name: NameFull: McVey ED – PersonEntity: Name: NameFull: Firoozabadi R – PersonEntity: Name: NameFull: Agel J – PersonEntity: Name: NameFull: Whiting PS – PersonEntity: Name: NameFull: Haleem A – PersonEntity: Name: NameFull: Domes C – PersonEntity: Name: NameFull: Lang GJ – PersonEntity: Name: NameFull: Kuhn GR – PersonEntity: Name: NameFull: Archer KR – PersonEntity: Name: NameFull: Talbot T – PersonEntity: Name: NameFull: Burgos EJ – PersonEntity: Name: NameFull: Gajari V – PersonEntity: Name: NameFull: Herrera LN – PersonEntity: Name: NameFull: Rodriguez-Buitrago A – PersonEntity: Name: NameFull: Tummuru RR – PersonEntity: Name: NameFull: Abraham CM – PersonEntity: Name: NameFull: Trochez KM IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: 2025 Mar 01 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2168-6262 Numbering: – Type: volume Value: 160 – Type: issue Value: 3 Titles: – TitleFull: JAMA surgery Type: main |
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