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Multiscale footprints reveal the organization of cis-regulatory elements.

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Title: Multiscale footprints reveal the organization of cis-regulatory elements.
Authors: Hu Y; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Horlbeck MA; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA., Zhang R; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Eric and Wendy Schmidt Center, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ma S; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Shrestha R; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Kartha VK; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Duarte FM; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Hock C; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Savage RE; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Labade A; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Kletzien H; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA., Meliki A; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Castillo A; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Durand NC; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Mattei E; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Anderson LJ; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Tay T; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Earl AS; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Shoresh N; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Epstein CB; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Wagers AJ; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA., Buenrostro JD; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA. jason_buenrostro@harvard.edu.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA. jason_buenrostro@harvard.edu.
Source: Nature [Nature] 2025 Feb; Vol. 638 (8051), pp. 779-786. Date of Electronic Publication: 2025 Jan 22.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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