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The risks of adverse events with mirtazapine for adults with major depressive disorder: a systematic review with meta-analysis and trial sequential analysis.

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Title: The risks of adverse events with mirtazapine for adults with major depressive disorder: a systematic review with meta-analysis and trial sequential analysis.
Authors: Kamp CB; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark. caroline.kamp@ctu.dk.; Department of Regional Health Research, The Faculty of Health Sciences, University of Southern Denmark, Odense, DK-5000, Denmark. caroline.kamp@ctu.dk., Petersen JJ; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark., Faltermeier P; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark.; MSH Medical School Hamburg, University of Applied Sciences and Medical University, 20457, Hamburg, Germany., Juul S; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark.; Stolpegaard Psychotherapy Centre, Mental Health Services in the Capital Region of Denmark, Gentofte, DK-2820, Denmark.; Department of Psychology, University of Copenhagen, Copenhagen, Denmark., Sillassen CDB; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark.; Department of Regional Health Research, The Faculty of Health Sciences, University of Southern Denmark, Odense, DK-5000, Denmark.; Department of Cardiology and Endocrinology, Slagelse Hospital, Region of Zealand, Slagelse, DK-4200, Denmark., Siddiqui F; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark., Andersen RK; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark., Moncrieff J; Division of Psychiatry (This position is honorary for MAH), University College London, London, W1T 7BN, UK.; Research and Development Department, North East London NHS Foundation Trust (NELFT), London, RM13 8EU, UK., Horowitz MA; Division of Psychiatry (This position is honorary for MAH), University College London, London, W1T 7BN, UK.; Research and Development Department, North East London NHS Foundation Trust (NELFT), London, RM13 8EU, UK., Hengartner MP; Department of Applied Psychology, Zurich University of Applied Sciences, Zurich, 8005, Switzerland., Kirsch I; Program in Placebo Studies, Harvard Medical School, Boston, MA, 02215, USA., Gluud C; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark.; Department of Regional Health Research, The Faculty of Health Sciences, University of Southern Denmark, Odense, DK-5000, Denmark., Jakobsen JC; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark.; Department of Regional Health Research, The Faculty of Health Sciences, University of Southern Denmark, Odense, DK-5000, Denmark.
Source: BMC psychiatry [BMC Psychiatry] 2025 Jan 22; Vol. 25 (1), pp. 67. Date of Electronic Publication: 2025 Jan 22.
Publication Type: Journal Article; Meta-Analysis; Systematic Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968559 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-244X (Electronic) Linking ISSN: 1471244X NLM ISO Abbreviation: BMC Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The risks of adverse events with mirtazapine for adults with major depressive disorder: a systematic review with meta-analysis and trial sequential analysis.
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  Data: <searchLink fieldCode="AU" term="%22Kamp+CB%22">Kamp CB</searchLink>; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark. caroline.kamp@ctu.dk.; Department of Regional Health Research, The Faculty of Health Sciences, University of Southern Denmark, Odense, DK-5000, Denmark. caroline.kamp@ctu.dk.<br /><searchLink fieldCode="AU" term="%22Petersen+JJ%22">Petersen JJ</searchLink>; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark.<br /><searchLink fieldCode="AU" term="%22Faltermeier+P%22">Faltermeier P</searchLink>; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark.; MSH Medical School Hamburg, University of Applied Sciences and Medical University, 20457, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Juul+S%22">Juul S</searchLink>; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark.; Stolpegaard Psychotherapy Centre, Mental Health Services in the Capital Region of Denmark, Gentofte, DK-2820, Denmark.; Department of Psychology, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Sillassen+CDB%22">Sillassen CDB</searchLink>; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark.; Department of Regional Health Research, The Faculty of Health Sciences, University of Southern Denmark, Odense, DK-5000, Denmark.; Department of Cardiology and Endocrinology, Slagelse Hospital, Region of Zealand, Slagelse, DK-4200, Denmark.<br /><searchLink fieldCode="AU" term="%22Siddiqui+F%22">Siddiqui F</searchLink>; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark.<br /><searchLink fieldCode="AU" term="%22Andersen+RK%22">Andersen RK</searchLink>; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark.<br /><searchLink fieldCode="AU" term="%22Moncrieff+J%22">Moncrieff J</searchLink>; Division of Psychiatry (This position is honorary for MAH), University College London, London, W1T 7BN, UK.; Research and Development Department, North East London NHS Foundation Trust (NELFT), London, RM13 8EU, UK.<br /><searchLink fieldCode="AU" term="%22Horowitz+MA%22">Horowitz MA</searchLink>; Division of Psychiatry (This position is honorary for MAH), University College London, London, W1T 7BN, UK.; Research and Development Department, North East London NHS Foundation Trust (NELFT), London, RM13 8EU, UK.<br /><searchLink fieldCode="AU" term="%22Hengartner+MP%22">Hengartner MP</searchLink>; Department of Applied Psychology, Zurich University of Applied Sciences, Zurich, 8005, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kirsch+I%22">Kirsch I</searchLink>; Program in Placebo Studies, Harvard Medical School, Boston, MA, 02215, USA.<br /><searchLink fieldCode="AU" term="%22Gluud+C%22">Gluud C</searchLink>; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark.; Department of Regional Health Research, The Faculty of Health Sciences, University of Southern Denmark, Odense, DK-5000, Denmark.<br /><searchLink fieldCode="AU" term="%22Jakobsen+JC%22">Jakobsen JC</searchLink>; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark.; Department of Regional Health Research, The Faculty of Health Sciences, University of Southern Denmark, Odense, DK-5000, Denmark.
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  Data: <searchLink fieldCode="JN" term="%22100968559%22">BMC psychiatry</searchLink> [BMC Psychiatry] 2025 Jan 22; Vol. 25 (1), pp. 67. <i>Date of Electronic Publication: </i>2025 Jan 22.
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