Aging and inflammation limit the induction of SARS-CoV-2-specific CD8+ T cell responses in severe COVID-19.
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| Title: | Aging and inflammation limit the induction of SARS-CoV-2-specific CD8+ T cell responses in severe COVID-19. |
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| Authors: | Autaa G; University of Bordeaux, CNRS UMR 5164, INSERM ERL 1303, ImmunoConcEpT, 33000 Bordeaux, France., Papagno L; University of Bordeaux, CNRS UMR 5164, INSERM ERL 1303, ImmunoConcEpT, 33000 Bordeaux, France., Nogimori T; Laboratory of Precision Immunology, Center for Intractable Diseases and ImmunoGenomics, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan., Boizard-Moracchini A; CHU Bordeaux, Laboratory of Immunology and Immunogenetics, 33000 Bordeaux, France., Korenkov D; University of Bordeaux, CNRS UMR 5164, INSERM ERL 1303, ImmunoConcEpT, 33000 Bordeaux, France., Roy M; CHU Bordeaux, Laboratory of Immunology and Immunogenetics, 33000 Bordeaux, France., Suzuki K; The Research Foundation for Microbial Diseases of Osaka University (BIKEN), Osaka, Japan., Masuta Y; Laboratory of Precision Immunology, Center for Intractable Diseases and ImmunoGenomics, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan., White E; University of Bordeaux, CNRS UMR 5164, INSERM ERL 1303, ImmunoConcEpT, 33000 Bordeaux, France., Llewellyn-Lacey S; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom., Yoshioka Y; The Research Foundation for Microbial Diseases of Osaka University (BIKEN), Osaka, Japan.; Vaccine Creation Group, BIKEN Innovative Vaccine Research Alliance Laboratories, Research Institute for Microbial Diseases.; Laboratory of Nano-Design for Innovative Drug Development, Graduate School of Pharmaceutical Sciences, and.; Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Osaka, Japan., Nicoli F; Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Ferrara, Italy., Price DA; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom.; Systems Immunity Research Institute, Cardiff University School of Medicine, Cardiff, United Kingdom., Dechanet-Merville J; University of Bordeaux, CNRS UMR 5164, INSERM ERL 1303, ImmunoConcEpT, 33000 Bordeaux, France., Yamamoto T; Laboratory of Precision Immunology, Center for Intractable Diseases and ImmunoGenomics, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan., Pellegrin I; University of Bordeaux, CNRS UMR 5164, INSERM ERL 1303, ImmunoConcEpT, 33000 Bordeaux, France.; CHU Bordeaux, Laboratory of Immunology and Immunogenetics, 33000 Bordeaux, France., Appay V; University of Bordeaux, CNRS UMR 5164, INSERM ERL 1303, ImmunoConcEpT, 33000 Bordeaux, France.; Laboratory of Precision Immunology, Center for Intractable Diseases and ImmunoGenomics, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan. |
| Source: | JCI insight [JCI Insight] 2025 Jan 23; Vol. 10 (4). Date of Electronic Publication: 2025 Jan 23. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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