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Efficacy and safety of JMT103 in patients with bone metastases from solid tumors: A randomized Phase Ib clinical trial.

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Title: Efficacy and safety of JMT103 in patients with bone metastases from solid tumors: A randomized Phase Ib clinical trial.
Authors: Ran R; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Breast Oncology, Peking University Cancer Hospital and Institute, Beijing, China., Li H; Department of Surgical Oncology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China., Sun T; Cancer Hospital of Dalian University of Technology, Liaoning Cancer Hospital and Institute, Shenyang, China., Zhou H; Department of Surgical Oncology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China., Zang A; Department of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, China., Guo H; Department of Urology, Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School, Nanjing, China.; Institute of Urology, Nanjing University, Nanjing, China., Xie H; Department of Oncology, Xuancheng People's Hospital, Affiliated Xuancheng Hospital of Wannan Medical College, Xuancheng, China., Wu S; Department of Medical Oncology, Peking University First Hospital, Beijing, China., Yan Y; Department of Urology, Beijing Shijitan Hospital, Beijing, China., Yin X; Department of Medical Oncology, Handan First Hospital, Handan, China., Xiong H; Department of Medical Oncology, Huizhou Central People's Hospital, Huizhou, China., Li H; CSPC ZhongQi Pharmaceutical Technology (Shijiazhuang) Co., Ltd., Shijiazhuang, China., Yuan J; CSPC ZhongQi Pharmaceutical Technology (Shijiazhuang) Co., Ltd., Shijiazhuang, China., Wang J; CSPC ZhongQi Pharmaceutical Technology (Shijiazhuang) Co., Ltd., Shijiazhuang, China., Li H; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Breast Oncology, Peking University Cancer Hospital and Institute, Beijing, China., Li J; Department of Medical Oncology, Shanghai East Hospital of Tongji University, Shanghai, China.
Source: International journal of cancer [Int J Cancer] 2025 Jun 01; Vol. 156 (11), pp. 2178-2187. Date of Electronic Publication: 2025 Jan 23.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy and safety of JMT103 in patients with bone metastases from solid tumors: A randomized Phase Ib clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22Ran+R%22">Ran R</searchLink>; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Breast Oncology, Peking University Cancer Hospital and Institute, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Department of Surgical Oncology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.<br /><searchLink fieldCode="AU" term="%22Sun+T%22">Sun T</searchLink>; Cancer Hospital of Dalian University of Technology, Liaoning Cancer Hospital and Institute, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Zhou+H%22">Zhou H</searchLink>; Department of Surgical Oncology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.<br /><searchLink fieldCode="AU" term="%22Zang+A%22">Zang A</searchLink>; Department of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, China.<br /><searchLink fieldCode="AU" term="%22Guo+H%22">Guo H</searchLink>; Department of Urology, Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School, Nanjing, China.; Institute of Urology, Nanjing University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Xie+H%22">Xie H</searchLink>; Department of Oncology, Xuancheng People's Hospital, Affiliated Xuancheng Hospital of Wannan Medical College, Xuancheng, China.<br /><searchLink fieldCode="AU" term="%22Wu+S%22">Wu S</searchLink>; Department of Medical Oncology, Peking University First Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Yan+Y%22">Yan Y</searchLink>; Department of Urology, Beijing Shijitan Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Yin+X%22">Yin X</searchLink>; Department of Medical Oncology, Handan First Hospital, Handan, China.<br /><searchLink fieldCode="AU" term="%22Xiong+H%22">Xiong H</searchLink>; Department of Medical Oncology, Huizhou Central People's Hospital, Huizhou, China.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; CSPC ZhongQi Pharmaceutical Technology (Shijiazhuang) Co., Ltd., Shijiazhuang, China.<br /><searchLink fieldCode="AU" term="%22Yuan+J%22">Yuan J</searchLink>; CSPC ZhongQi Pharmaceutical Technology (Shijiazhuang) Co., Ltd., Shijiazhuang, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; CSPC ZhongQi Pharmaceutical Technology (Shijiazhuang) Co., Ltd., Shijiazhuang, China.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Breast Oncology, Peking University Cancer Hospital and Institute, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Medical Oncology, Shanghai East Hospital of Tongji University, Shanghai, China.
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  Data: <searchLink fieldCode="JN" term="%220042124%22">International journal of cancer</searchLink> [Int J Cancer] 2025 Jun 01; Vol. 156 (11), pp. 2178-2187. <i>Date of Electronic Publication: </i>2025 Jan 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Liss%22">Wiley-Liss </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0042124 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-0215 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200207136%22">00207136 </searchLink><i>NLM ISO Abbreviation: </i>Int J Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1002/ijc.35343
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            – D: 01
              M: 06
              Text: 2025 Jun 01
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              Y: 2025
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