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Inhibition of acyl-CoA synthetase long-chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction.

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Title: Inhibition of acyl-CoA synthetase long-chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction.
Authors: Murphy CS; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA., Fairfield H; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; School of Medicine, Tufts University, Boston, MA, USA., DeMambro VE; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA., Fadel S; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; School of Medicine, Tufts University, Boston, MA, USA.; University of New England, Biddeford, ME, USA., Gartner CA; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA., Karam M; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA., Potts C; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA., Rodriguez P; Vermont Integrative Genomics Resource DNA Facility, University of Vermont, Burlington, VT, USA., Qiang YW; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA., Hamidi H; Genentech, Inc., San Francisco, CA, USA., Guan X; Genentech, Inc., San Francisco, CA, USA., Vary CPH; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA.; School of Medicine, Tufts University, Boston, MA, USA., Reagan MR; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA.; School of Medicine, Tufts University, Boston, MA, USA.
Source: Molecular oncology [Mol Oncol] 2025 Jun; Vol. 19 (6), pp. 1687-1706. Date of Electronic Publication: 2025 Jan 23.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Inhibition of acyl-CoA synthetase long-chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction.
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  Data: <searchLink fieldCode="AU" term="%22Murphy+CS%22">Murphy CS</searchLink>; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA.<br /><searchLink fieldCode="AU" term="%22Fairfield+H%22">Fairfield H</searchLink>; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; School of Medicine, Tufts University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22DeMambro+VE%22">DeMambro VE</searchLink>; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA.<br /><searchLink fieldCode="AU" term="%22Fadel+S%22">Fadel S</searchLink>; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; School of Medicine, Tufts University, Boston, MA, USA.; University of New England, Biddeford, ME, USA.<br /><searchLink fieldCode="AU" term="%22Gartner+CA%22">Gartner CA</searchLink>; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA.<br /><searchLink fieldCode="AU" term="%22Karam+M%22">Karam M</searchLink>; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.<br /><searchLink fieldCode="AU" term="%22Potts+C%22">Potts C</searchLink>; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.<br /><searchLink fieldCode="AU" term="%22Rodriguez+P%22">Rodriguez P</searchLink>; Vermont Integrative Genomics Resource DNA Facility, University of Vermont, Burlington, VT, USA.<br /><searchLink fieldCode="AU" term="%22Qiang+YW%22">Qiang YW</searchLink>; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.<br /><searchLink fieldCode="AU" term="%22Hamidi+H%22">Hamidi H</searchLink>; Genentech, Inc., San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Guan+X%22">Guan X</searchLink>; Genentech, Inc., San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Vary+CPH%22">Vary CPH</searchLink>; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA.; School of Medicine, Tufts University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Reagan+MR%22">Reagan MR</searchLink>; Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.; University of Maine Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA.; School of Medicine, Tufts University, Boston, MA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101308230%22">Molecular oncology</searchLink> [Mol Oncol] 2025 Jun; Vol. 19 (6), pp. 1687-1706. <i>Date of Electronic Publication: </i>2025 Jan 23.
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