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Polygenic risk discriminates Lewy body dementia from Alzheimer's disease.

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Title: Polygenic risk discriminates Lewy body dementia from Alzheimer's disease.
Authors: McKeever A; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK., Swann P; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK., Malpetti M; Department of Clinical Neurosciences, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Donaghy PC; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Thomas A; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Mak E; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK., Carter SF; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK., Tan JHK; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK., Hong YT; Department of Clinical Neurosciences, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Fryer TD; Department of Clinical Neurosciences, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Heslegrave A; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.; Dementia Research Institute, UCL, London, UK., Zetterberg H; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.; Dementia Research Institute, UCL, London, UK.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Gothenburg, Sweden.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong Science Park, Hong Kong, Hong Kong.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA., Su L; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Neuroscience Institute, University of Sheffield, Sheffield, UK., Chouliaras L; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Specialist Dementia and Frailty Service, Essex Partnership University NHS Foundation Trust, Essex, UK., Rowe JB; Department of Clinical Neurosciences, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., O'Brien JT; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Feb; Vol. 21 (2), pp. e14381. Date of Electronic Publication: 2025 Jan 24.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22McKeever+A%22">McKeever A</searchLink>; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Swann+P%22">Swann P</searchLink>; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Malpetti+M%22">Malpetti M</searchLink>; Department of Clinical Neurosciences, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Donaghy+PC%22">Donaghy PC</searchLink>; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Thomas+A%22">Thomas A</searchLink>; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Mak+E%22">Mak E</searchLink>; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Carter+SF%22">Carter SF</searchLink>; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Tan+JHK%22">Tan JHK</searchLink>; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Hong+YT%22">Hong YT</searchLink>; Department of Clinical Neurosciences, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Fryer+TD%22">Fryer TD</searchLink>; Department of Clinical Neurosciences, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Heslegrave+A%22">Heslegrave A</searchLink>; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.; Dementia Research Institute, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22Zetterberg+H%22">Zetterberg H</searchLink>; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.; Dementia Research Institute, UCL, London, UK.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Gothenburg, Sweden.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong Science Park, Hong Kong, Hong Kong.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Su+L%22">Su L</searchLink>; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Neuroscience Institute, University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Chouliaras+L%22">Chouliaras L</searchLink>; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Specialist Dementia and Frailty Service, Essex Partnership University NHS Foundation Trust, Essex, UK.<br /><searchLink fieldCode="AU" term="%22Rowe+JB%22">Rowe JB</searchLink>; Department of Clinical Neurosciences, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22O'Brien+JT%22">O'Brien JT</searchLink>; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
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