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Low agreement and frequent invalid controls in two SARS-CoV-2 T-cell assays in people with compromised immune function.

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Title: Low agreement and frequent invalid controls in two SARS-CoV-2 T-cell assays in people with compromised immune function.
Authors: Audigé A; Institute of Medical Virology, University of Zurich, Zurich, Switzerland., Amstutz A; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.; Oslo Center for Biostatistics and Epidemiology (OCBE), Oslo University Hospital, University of Oslo, Oslo, Norway.; Bristol Medical School, University of Bristol, Bristol, United Kingdom., Schuurmans MM; Division of Pulmonology, University Hospital Zurich, Zurich, Switzerland., Amico P; Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland., Braun DL; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland., Stoeckle MP; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Basel, Switzerland., Hasse B; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland., Hage R; Division of Pulmonology, University Hospital Zurich, Zurich, Switzerland., Damm D; Division of Pulmonology, University Hospital Zurich, Zurich, Switzerland., Tamm M; Clinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital Basel, Basel, Switzerland., Mueller NJ; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland., Günthard HF; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland., Koller MT; Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.; Swiss Transplant Cohort Study, University Hospital Basel, Basel, Switzerland., Schönenberger CM; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland., Griessbach A; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland., Labhardt ND; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland., Kouyos RD; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland., Trkola A; Institute of Medical Virology, University of Zurich, Zurich, Switzerland., Huber M; Institute of Medical Virology, University of Zurich, Zurich, Switzerland., Kusejko K; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland., Bucher HC; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland., Abela IA; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland., Briel M; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada., Chammartin F; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland., Speich B; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.
Corporate Authors: Swiss HIV Cohort Study, and the Swiss Transplant Cohort Study
Source: PloS one [PLoS One] 2025 Jan 24; Vol. 20 (1), pp. e0317965. Date of Electronic Publication: 2025 Jan 24 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Audigé+A%22">Audigé A</searchLink>; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Amstutz+A%22">Amstutz A</searchLink>; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.; Oslo Center for Biostatistics and Epidemiology (OCBE), Oslo University Hospital, University of Oslo, Oslo, Norway.; Bristol Medical School, University of Bristol, Bristol, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Schuurmans+MM%22">Schuurmans MM</searchLink>; Division of Pulmonology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Amico+P%22">Amico P</searchLink>; Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Braun+DL%22">Braun DL</searchLink>; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Stoeckle+MP%22">Stoeckle MP</searchLink>; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hasse+B%22">Hasse B</searchLink>; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hage+R%22">Hage R</searchLink>; Division of Pulmonology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Damm+D%22">Damm D</searchLink>; Division of Pulmonology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tamm+M%22">Tamm M</searchLink>; Clinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mueller+NJ%22">Mueller NJ</searchLink>; 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Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kouyos+RD%22">Kouyos RD</searchLink>; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Trkola+A%22">Trkola A</searchLink>; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Huber+M%22">Huber M</searchLink>; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kusejko+K%22">Kusejko K</searchLink>; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bucher+HC%22">Bucher HC</searchLink>; 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