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A proposed screening strategy for evaluating the genotoxicity potential of botanicals and botanical extracts.

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Title: A proposed screening strategy for evaluating the genotoxicity potential of botanicals and botanical extracts.
Authors: Witt KL; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA., van Benthem J; National Institute for Public Health and the Environment (RIVM), Beethoven, the Netherlands., Kobets T; Department of Pathology, New York Medical College, Valhalla, NY, 10595, USA., Chen G; Human Safety Division, Veterinary Drugs Directorate, Health Products and Food Branch, Health Canada, Ottawa, Canada., Kelber O; Bayer Consumer Health, Steigerwald Arzneimittelwerk GmbH, Darmstadt, Germany., Krzykwa J; Health and Environmental Sciences Institute, Washington, DC, USA., MacGregor JT; Toxicology Consulting Services, Bonita Springs, FL, USA., Mei N; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA., Mitchell CA; Health and Environmental Sciences Institute, Washington, DC, USA. Electronic address: cmitchell@hesiglobal.org., Rietjens I; Division of Toxicology, Wageningen University, Wageningen, the Netherlands., Sarigol-Kilic Z; L'Oréal Group, Research & Innovation, Clark, NJ, 07066, USA., Smith-Roe SL; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA., Stopper H; Institute of Pharmacology and Toxicology, University of Wuerzburg, Wuerzburg, Germany., Thakkar Y; Research Institute for Fragrance Materials, Inc., Woodcliff Lake, NJ, USA., Zeiger E; Errol Zeiger Consulting, Chapel Hill, NC, USA., Pfuhler S; The Procter & Gamble Company, Mason, OH, USA.
Source: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2025 Mar; Vol. 197, pp. 115277. Date of Electronic Publication: 2025 Jan 23.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8207483 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6351 (Electronic) Linking ISSN: 02786915 NLM ISO Abbreviation: Food Chem Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A proposed screening strategy for evaluating the genotoxicity potential of botanicals and botanical extracts.
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  Data: <searchLink fieldCode="AU" term="%22Witt+KL%22">Witt KL</searchLink>; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.<br /><searchLink fieldCode="AU" term="%22van+Benthem+J%22">van Benthem J</searchLink>; National Institute for Public Health and the Environment (RIVM), Beethoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kobets+T%22">Kobets T</searchLink>; Department of Pathology, New York Medical College, Valhalla, NY, 10595, USA.<br /><searchLink fieldCode="AU" term="%22Chen+G%22">Chen G</searchLink>; Human Safety Division, Veterinary Drugs Directorate, Health Products and Food Branch, Health Canada, Ottawa, Canada.<br /><searchLink fieldCode="AU" term="%22Kelber+O%22">Kelber O</searchLink>; Bayer Consumer Health, Steigerwald Arzneimittelwerk GmbH, Darmstadt, Germany.<br /><searchLink fieldCode="AU" term="%22Krzykwa+J%22">Krzykwa J</searchLink>; Health and Environmental Sciences Institute, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22MacGregor+JT%22">MacGregor JT</searchLink>; Toxicology Consulting Services, Bonita Springs, FL, USA.<br /><searchLink fieldCode="AU" term="%22Mei+N%22">Mei N</searchLink>; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA.<br /><searchLink fieldCode="AU" term="%22Mitchell+CA%22">Mitchell CA</searchLink>; Health and Environmental Sciences Institute, Washington, DC, USA. Electronic address: cmitchell@hesiglobal.org.<br /><searchLink fieldCode="AU" term="%22Rietjens+I%22">Rietjens I</searchLink>; Division of Toxicology, Wageningen University, Wageningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Sarigol-Kilic+Z%22">Sarigol-Kilic Z</searchLink>; L'Oréal Group, Research & Innovation, Clark, NJ, 07066, USA.<br /><searchLink fieldCode="AU" term="%22Smith-Roe+SL%22">Smith-Roe SL</searchLink>; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.<br /><searchLink fieldCode="AU" term="%22Stopper+H%22">Stopper H</searchLink>; Institute of Pharmacology and Toxicology, University of Wuerzburg, Wuerzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Thakkar+Y%22">Thakkar Y</searchLink>; Research Institute for Fragrance Materials, Inc., Woodcliff Lake, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Zeiger+E%22">Zeiger E</searchLink>; Errol Zeiger Consulting, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Pfuhler+S%22">Pfuhler S</searchLink>; The Procter & Gamble Company, Mason, OH, USA.
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