Lipopolysaccharide (LPS) induces sclerostin secretion by extracellular vesicle via TLR4/miR-92a-3p/PTEN/NF-κB signalling pathway in murine macrophage.

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Title: Lipopolysaccharide (LPS) induces sclerostin secretion by extracellular vesicle via TLR4/miR-92a-3p/PTEN/NF-κB signalling pathway in murine macrophage.
Authors: Kwok CT; Department of Food Science and Nutrition, The Hong Kong Polytechnic University, Hong Kong, SAR, China., Wong CC; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, SAR, China., Li JJ; Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, SAR, China.; The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen, China., Kwan YW; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, SAR, China., Leung GP; Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong, SAR, China., Tsoi B; Department of Food Science and Nutrition, The Hong Kong Polytechnic University, Hong Kong, SAR, China.; Research Centre for Chinese Medicine Innovation, The Hong Kong Polytechnic University, Hong Kong, SAR, China., Chow FW; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, SAR, China. franklin.chow@polyu.edu.hk., Seto SW; Department of Food Science and Nutrition, The Hong Kong Polytechnic University, Hong Kong, SAR, China. sai.seto@uwa.edu.au.; Research Centre for Chinese Medicine Innovation, The Hong Kong Polytechnic University, Hong Kong, SAR, China. sai.seto@uwa.edu.au.; NICM Health Research Institute, Western Sydney University, Penrith, NSW, 2751, Australia. sai.seto@uwa.edu.au.; School of Biomedical Sciences, The University of Western Australia, Perth, WA, Australia. sai.seto@uwa.edu.au.
Source: Inflammation research : official journal of the European Histamine Research Society ... [et al.] [Inflamm Res] 2025 Jan 25; Vol. 74 (1), pp. 27. Date of Electronic Publication: 2025 Jan 25.
Publication Type: Journal Article
Journal Info: Publisher: Birkhäuser Country of Publication: Switzerland NLM ID: 9508160 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-908X (Electronic) Linking ISSN: 10233830 NLM ISO Abbreviation: Inflamm Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1420-908X
DOI:10.1007/s00011-024-01987-1