Novel Flow Cytometric Antibody Panel and Dedicated Analysis Algorithm for Automated Fully Standardized Minimal Residual Disease Detection in Chronic Lymphocytic Leukemia.

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Title: Novel Flow Cytometric Antibody Panel and Dedicated Analysis Algorithm for Automated Fully Standardized Minimal Residual Disease Detection in Chronic Lymphocytic Leukemia.
Authors: Engelmann R; Clinic III (Hematology, Oncology and Palliative Medicine), Special Hematology Laboratory, Rostock University Medical School, Rostock, Germany., Flores-Montero J; Clinical and Translational Research Program, Cancer Research Center (IBMCC-CSIC/USAL-IBSAL), University of Salamanca, Salamanca, Spain.; Department of Medicine, Cytometry Service (NUCLEUS) and Institute for Biomedical Research of Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.; Centro de Investigacion Biomedica en Red de Cancer (CIBER-ONC) (CB16/12/00400), Institudo de Salud Carlos III, Madrid, Spain., Schilperoord-Vermeulen J; Laboratory Medical Immunology, Department of Immunology, Erasmus MC, Rotterdam, the Netherlands., Ritgen M; Department of Internal Medicine II, University of Schleswig-Holstein, Kiel, Germany., Hengeveld PJ; Laboratory Medical Immunology, Department of Immunology, Erasmus MC, Rotterdam, the Netherlands., Kohlscheen S; Department of Internal Medicine II, University of Schleswig-Holstein, Kiel, Germany., Grigore G; Becton Dickinson R&D, Salamanca, Spain., Rodriguez RF; Becton Dickinson R&D, Salamanca, Spain., Lecrevisse Q; Clinical and Translational Research Program, Cancer Research Center (IBMCC-CSIC/USAL-IBSAL), University of Salamanca, Salamanca, Spain.; Department of Medicine, Cytometry Service (NUCLEUS) and Institute for Biomedical Research of Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.; Centro de Investigacion Biomedica en Red de Cancer (CIBER-ONC) (CB16/12/00400), Institudo de Salud Carlos III, Madrid, Spain.; Department of Medicine, University of Salamanca (Universidad de Salamanca), Salamanca, Spain., Philippé J; Department of Diagnostic Sciences, Ghent University, Ghent, Belgium., Villamor N; Hematopathology Unit, Department of Pathology, Hospital Clínic of Barcelona, Barcelona, Spain., Fernandez P; FACS/Stem Cell Laboratory, Kantonsspital Aarau AG, Aarau, Switzerland., Burgos L; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC Number CB16/12/00369, Pamplona, Spain., van Dongen JJM; Department of Medicine, Cytometry Service (NUCLEUS) and Institute for Biomedical Research of Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.; European Scientific Foundation for Laboratory Hemato-Oncology, Zutphen, the Netherlands., Orfao A; Clinical and Translational Research Program, Cancer Research Center (IBMCC-CSIC/USAL-IBSAL), University of Salamanca, Salamanca, Spain.; Department of Medicine, Cytometry Service (NUCLEUS) and Institute for Biomedical Research of Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.; Centro de Investigacion Biomedica en Red de Cancer (CIBER-ONC) (CB16/12/00400), Institudo de Salud Carlos III, Madrid, Spain., Langerak AW; Laboratory Medical Immunology, Department of Immunology, Erasmus MC, Rotterdam, the Netherlands., Böttcher S; Clinic III (Hematology, Oncology and Palliative Medicine), Special Hematology Laboratory, Rostock University Medical School, Rostock, Germany.
Corporate Authors: EuroFlow Consortium
Source: American journal of hematology [Am J Hematol] 2025 Apr; Vol. 100 (4), pp. 724-728. Date of Electronic Publication: 2025 Jan 25.
Publication Type: Letter
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 7610369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-8652 (Electronic) Linking ISSN: 03618609 NLM ISO Abbreviation: Am J Hematol Subsets: MEDLINE; In Process
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  Data: Novel Flow Cytometric Antibody Panel and Dedicated Analysis Algorithm for Automated Fully Standardized Minimal Residual Disease Detection in Chronic Lymphocytic Leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Engelmann+R%22">Engelmann R</searchLink>; Clinic III (Hematology, Oncology and Palliative Medicine), Special Hematology Laboratory, Rostock University Medical School, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Flores-Montero+J%22">Flores-Montero J</searchLink>; Clinical and Translational Research Program, Cancer Research Center (IBMCC-CSIC/USAL-IBSAL), University of Salamanca, Salamanca, Spain.; Department of Medicine, Cytometry Service (NUCLEUS) and Institute for Biomedical Research of Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.; Centro de Investigacion Biomedica en Red de Cancer (CIBER-ONC) (CB16/12/00400), Institudo de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Schilperoord-Vermeulen+J%22">Schilperoord-Vermeulen J</searchLink>; Laboratory Medical Immunology, Department of Immunology, Erasmus MC, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Ritgen+M%22">Ritgen M</searchLink>; Department of Internal Medicine II, University of Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Hengeveld+PJ%22">Hengeveld PJ</searchLink>; Laboratory Medical Immunology, Department of Immunology, Erasmus MC, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kohlscheen+S%22">Kohlscheen S</searchLink>; Department of Internal Medicine II, University of Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Grigore+G%22">Grigore G</searchLink>; Becton Dickinson R&D, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Rodriguez+RF%22">Rodriguez RF</searchLink>; Becton Dickinson R&D, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Lecrevisse+Q%22">Lecrevisse Q</searchLink>; Clinical and Translational Research Program, Cancer Research Center (IBMCC-CSIC/USAL-IBSAL), University of Salamanca, Salamanca, Spain.; Department of Medicine, Cytometry Service (NUCLEUS) and Institute for Biomedical Research of Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.; Centro de Investigacion Biomedica en Red de Cancer (CIBER-ONC) (CB16/12/00400), Institudo de Salud Carlos III, Madrid, Spain.; Department of Medicine, University of Salamanca (Universidad de Salamanca), Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Philippé+J%22">Philippé J</searchLink>; Department of Diagnostic Sciences, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Villamor+N%22">Villamor N</searchLink>; Hematopathology Unit, Department of Pathology, Hospital Clínic of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Fernandez+P%22">Fernandez P</searchLink>; FACS/Stem Cell Laboratory, Kantonsspital Aarau AG, Aarau, Switzerland.<br /><searchLink fieldCode="AU" term="%22Burgos+L%22">Burgos L</searchLink>; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC Number CB16/12/00369, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22van+Dongen+JJM%22">van Dongen JJM</searchLink>; Department of Medicine, Cytometry Service (NUCLEUS) and Institute for Biomedical Research of Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.; European Scientific Foundation for Laboratory Hemato-Oncology, Zutphen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Orfao+A%22">Orfao A</searchLink>; Clinical and Translational Research Program, Cancer Research Center (IBMCC-CSIC/USAL-IBSAL), University of Salamanca, Salamanca, Spain.; Department of Medicine, Cytometry Service (NUCLEUS) and Institute for Biomedical Research of Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.; Centro de Investigacion Biomedica en Red de Cancer (CIBER-ONC) (CB16/12/00400), Institudo de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Langerak+AW%22">Langerak AW</searchLink>; Laboratory Medical Immunology, Department of Immunology, Erasmus MC, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Böttcher+S%22">Böttcher S</searchLink>; Clinic III (Hematology, Oncology and Palliative Medicine), Special Hematology Laboratory, Rostock University Medical School, Rostock, Germany.
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              Text: 2025 Apr
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