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NOTCH1 Mutations Are Associated With Therapy-Resistance in Patients With B-Cell Lymphoma Treated With CD20xCD3 Bispecific Antibodies.

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Title: NOTCH1 Mutations Are Associated With Therapy-Resistance in Patients With B-Cell Lymphoma Treated With CD20xCD3 Bispecific Antibodies.
Authors: Kyvsgaard ER; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark.; Phase 1 Unit, Rigshospitalet, Copenhagen, Denmark.; Department of Internal Medicine, Aalborg University Hospital Thisted, Thisted, Denmark., Grauslund M; Department of Pathology, Rigshospitalet, Copenhagen, Denmark., Sjø L; Department of Pathology, Rigshospitalet, Copenhagen, Denmark., Melchior LC; Department of Pathology, Rigshospitalet, Copenhagen, Denmark., Grantzau TL; Department of Pathology, Rigshospitalet, Copenhagen, Denmark., Gjerdrum LMR; Department of Pathology, Copenhagen University Hospital-Zealand University Hospital, Roskilde, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Trab T; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark., Andersen LS; Department of Hematology, Rigshospitalet, Copenhagen, Denmark., Gang AO; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Breinholt M; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Department of Pathology, Herlev Gentofte Hospital, Denmark., Møller MB; Department of Pathology, Odense University Hospital, Odense, Denmark., Haaber Christensen J; Department of Hematology, Odense University Hospital, Odense, Denmark., Larsen TS; Department of Hematology, Odense University Hospital, Odense, Denmark., Clausen MR; Department of Hematology, Vejle Sygehus, Vejle, Denmark., Riley CH; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Phase 1 Unit, Rigshospitalet, Copenhagen, Denmark., Niemann CU; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Grønbæk K; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Hutchings M; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Phase 1 Unit, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Husby S; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark.; Phase 1 Unit, Rigshospitalet, Copenhagen, Denmark.
Source: American journal of hematology [Am J Hematol] 2025 Apr; Vol. 100 (4), pp. 712-716. Date of Electronic Publication: 2025 Jan 25.
Publication Type: Letter
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 7610369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-8652 (Electronic) Linking ISSN: 03618609 NLM ISO Abbreviation: Am J Hematol Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: NOTCH1 Mutations Are Associated With Therapy-Resistance in Patients With B-Cell Lymphoma Treated With CD20xCD3 Bispecific Antibodies.
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  Data: <searchLink fieldCode="AU" term="%22Kyvsgaard+ER%22">Kyvsgaard ER</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark.; Phase 1 Unit, Rigshospitalet, Copenhagen, Denmark.; Department of Internal Medicine, Aalborg University Hospital Thisted, Thisted, Denmark.<br /><searchLink fieldCode="AU" term="%22Grauslund+M%22">Grauslund M</searchLink>; Department of Pathology, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Sjø+L%22">Sjø L</searchLink>; Department of Pathology, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Melchior+LC%22">Melchior LC</searchLink>; Department of Pathology, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Grantzau+TL%22">Grantzau TL</searchLink>; Department of Pathology, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Gjerdrum+LMR%22">Gjerdrum LMR</searchLink>; Department of Pathology, Copenhagen University Hospital-Zealand University Hospital, Roskilde, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Trab+T%22">Trab T</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Andersen+LS%22">Andersen LS</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Gang+AO%22">Gang AO</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Breinholt+M%22">Breinholt M</searchLink>; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Department of Pathology, Herlev Gentofte Hospital, Denmark.<br /><searchLink fieldCode="AU" term="%22Møller+MB%22">Møller MB</searchLink>; Department of Pathology, Odense University Hospital, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Haaber+Christensen+J%22">Haaber Christensen J</searchLink>; Department of Hematology, Odense University Hospital, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Larsen+TS%22">Larsen TS</searchLink>; Department of Hematology, Odense University Hospital, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Clausen+MR%22">Clausen MR</searchLink>; Department of Hematology, Vejle Sygehus, Vejle, Denmark.<br /><searchLink fieldCode="AU" term="%22Riley+CH%22">Riley CH</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Phase 1 Unit, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Niemann+CU%22">Niemann CU</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Grønbæk+K%22">Grønbæk K</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Hutchings+M%22">Hutchings M</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Phase 1 Unit, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Husby+S%22">Husby S</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark.; Phase 1 Unit, Rigshospitalet, Copenhagen, Denmark.
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  Data: <searchLink fieldCode="JN" term="%227610369%22">American journal of hematology</searchLink> [Am J Hematol] 2025 Apr; Vol. 100 (4), pp. 712-716. <i>Date of Electronic Publication: </i>2025 Jan 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7610369 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1096-8652 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203618609%22">03618609 </searchLink><i>NLM ISO Abbreviation: </i>Am J Hematol <i>Subsets: </i>MEDLINE; In Process
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