BCG-Induced DNA Methylation Changes Improve Coronavirus Disease 2019 Vaccine Immunity Without Decreasing the Risk for Severe Acute Respiratory Syndrome Coronavirus 2 Infection.

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Title: BCG-Induced DNA Methylation Changes Improve Coronavirus Disease 2019 Vaccine Immunity Without Decreasing the Risk for Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
Authors: Carrero Longlax S; Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA., Koster KJ; Center for Airborne Pathogen Research and Imaging, Texas A&M School of Medicine, Bryan, Texas, USA., Kamat AM; Urology Department, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Lozano M; Urology Department, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Lerner SP; Scott Department of Urology, Baylor College of Medicine, Houston, Texas, USA., Hannigan R; Scott Department of Urology, Baylor College of Medicine, Houston, Texas, USA., Nishiguchi T; Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA., Abhimanyu; Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA., Sheikh D; Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA., Ladki M; Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA., Portillo A; Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA., Koirala A; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas, USA., Patel TD; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas, USA., Spieler Z; Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA., Benjamin AB; Center for Airborne Pathogen Research and Imaging, Texas A&M School of Medicine, Bryan, Texas, USA., Lebedev M; Center for Airborne Pathogen Research and Imaging, Texas A&M School of Medicine, Bryan, Texas, USA., Ofili TU; Department of Pharmacy Practice, Texas A&M School of Pharmacy, College Station, Texas, USA., Hutchison RW; Department of Pharmacy Practice, Texas A&M School of Pharmacy, College Station, Texas, USA., Udeani G; Department of Pharmacy Practice, Texas A&M School of Pharmacy, College Station, Texas, USA., Opperman LA; Department of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M School of Dentistry, Dallas, Texas, USA., Neal G; Primary Care and Rural Medicine, Texas A&M School of Medicine, Bryan, Texas, USA., Mandalakas AM; Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.; Clinical Infectious Diseases, Research Centre Borstel, Borstel, Germany.; Clinical Tuberculosis Unit, German Centre for Infection Research, Borstel, Germany., Netea MG; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands., Arditi M; Departments of Pediatrics and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA., Avalos P; Departments of Pediatrics and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA., Grimm SL; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA., Coarfa C; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA., Cirillo JD; Center for Airborne Pathogen Research and Imaging, Texas A&M School of Medicine, Bryan, Texas, USA., DiNardo AR; Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Source: Open forum infectious diseases [Open Forum Infect Dis] 2025 Jan 16; Vol. 12 (1), pp. ofaf007. Date of Electronic Publication: 2025 Jan 16 (Print Publication: 2025).
Publication Type: Clinical Trial; Journal Article
Journal Info: Publisher: Published by Oxford University Press on behalf of the Infectious Diseases Society of America Country of Publication: United States NLM ID: 101637045 Publication Model: eCollection Cited Medium: Print ISSN: 2328-8957 (Print) Linking ISSN: 23288957 NLM ISO Abbreviation: Open Forum Infect Dis Subsets: PubMed not MEDLINE
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  Data: BCG-Induced DNA Methylation Changes Improve Coronavirus Disease 2019 Vaccine Immunity Without Decreasing the Risk for Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
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Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Koster+KJ%22">Koster KJ</searchLink>; Center for Airborne Pathogen Research and Imaging, Texas A&M School of Medicine, Bryan, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Kamat+AM%22">Kamat AM</searchLink>; Urology Department, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Lozano+M%22">Lozano M</searchLink>; Urology Department, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Lerner+SP%22">Lerner SP</searchLink>; Scott Department of Urology, Baylor College of Medicine, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Hannigan+R%22">Hannigan R</searchLink>; Scott Department of Urology, Baylor College of Medicine, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Nishiguchi+T%22">Nishiguchi T</searchLink>; Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Abhimanyu%22">Abhimanyu</searchLink>; Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Sheikh+D%22">Sheikh D</searchLink>; Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Ladki+M%22">Ladki M</searchLink>; Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Portillo+A%22">Portillo A</searchLink>; Global Tuberculosis Program, William T. 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Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Benjamin+AB%22">Benjamin AB</searchLink>; Center for Airborne Pathogen Research and Imaging, Texas A&M School of Medicine, Bryan, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Lebedev+M%22">Lebedev M</searchLink>; Center for Airborne Pathogen Research and Imaging, Texas A&M School of Medicine, Bryan, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Ofili+TU%22">Ofili TU</searchLink>; Department of Pharmacy Practice, Texas A&M School of Pharmacy, College Station, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Hutchison+RW%22">Hutchison RW</searchLink>; Department of Pharmacy Practice, Texas A&M School of Pharmacy, College Station, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Udeani+G%22">Udeani G</searchLink>; Department of Pharmacy Practice, Texas A&M School of Pharmacy, College Station, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Opperman+LA%22">Opperman LA</searchLink>; Department of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M School of Dentistry, Dallas, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Neal+G%22">Neal G</searchLink>; Primary Care and Rural Medicine, Texas A&M School of Medicine, Bryan, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Mandalakas+AM%22">Mandalakas AM</searchLink>; Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.; Clinical Infectious Diseases, Research Centre Borstel, Borstel, Germany.; Clinical Tuberculosis Unit, German Centre for Infection Research, Borstel, Germany.<br /><searchLink fieldCode="AU" term="%22Netea+MG%22">Netea MG</searchLink>; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Arditi+M%22">Arditi M</searchLink>; Departments of Pediatrics and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Avalos+P%22">Avalos P</searchLink>; Departments of Pediatrics and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Grimm+SL%22">Grimm SL</searchLink>; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Coarfa+C%22">Coarfa C</searchLink>; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Cirillo+JD%22">Cirillo JD</searchLink>; Center for Airborne Pathogen Research and Imaging, Texas A&M School of Medicine, Bryan, Texas, USA.<br /><searchLink fieldCode="AU" term="%22DiNardo+AR%22">DiNardo AR</searchLink>; Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
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