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Frequently arising ESX-1-associated phase variants influence Mycobacterium tuberculosis fitness in the presence of host and antibiotic pressures.

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Title: Frequently arising ESX-1-associated phase variants influence Mycobacterium tuberculosis fitness in the presence of host and antibiotic pressures.
Authors: Luna MJ; Department of Microbiology, UMass Chan Medical School, Worcester, Massachusetts, USA., Oluoch PO; Department of Microbiology, UMass Chan Medical School, Worcester, Massachusetts, USA., Miao J; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Culviner P; Department of Immunology and Infectious Diseases, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA., Papavinasasundaram K; Department of Microbiology, UMass Chan Medical School, Worcester, Massachusetts, USA., Jaecklein E; Department of Microbiology, UMass Chan Medical School, Worcester, Massachusetts, USA., Shell SS; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts, USA., Ioerger TR; Department of Computer Science and Engineering, Texas A&M University, College Station, Texas, USA., Fortune SM; Department of Immunology and Infectious Diseases, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA., Farhat MR; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA.; Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Sassetti CM; Department of Microbiology, UMass Chan Medical School, Worcester, Massachusetts, USA.
Source: MBio [mBio] 2025 Mar 12; Vol. 16 (3), pp. e0376224. Date of Electronic Publication: 2025 Jan 28.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Luna+MJ%22">Luna MJ</searchLink>; Department of Microbiology, UMass Chan Medical School, Worcester, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Oluoch+PO%22">Oluoch PO</searchLink>; Department of Microbiology, UMass Chan Medical School, Worcester, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Miao+J%22">Miao J</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Culviner+P%22">Culviner P</searchLink>; Department of Immunology and Infectious Diseases, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Papavinasasundaram+K%22">Papavinasasundaram K</searchLink>; Department of Microbiology, UMass Chan Medical School, Worcester, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Jaecklein+E%22">Jaecklein E</searchLink>; Department of Microbiology, UMass Chan Medical School, Worcester, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Shell+SS%22">Shell SS</searchLink>; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Ioerger+TR%22">Ioerger TR</searchLink>; Department of Computer Science and Engineering, Texas A&M University, College Station, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Fortune+SM%22">Fortune SM</searchLink>; Department of Immunology and Infectious Diseases, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Farhat+MR%22">Farhat MR</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA.; Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Sassetti+CM%22">Sassetti CM</searchLink>; Department of Microbiology, UMass Chan Medical School, Worcester, Massachusetts, USA.
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  Data: <searchLink fieldCode="JN" term="%22101519231%22">MBio</searchLink> [mBio] 2025 Mar 12; Vol. 16 (3), pp. e0376224. <i>Date of Electronic Publication: </i>2025 Jan 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Microbiology%22">American Society for Microbiology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101519231 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2150-7511 (Electronic) <i>NLM ISO Abbreviation: </i>mBio <i>Subsets: </i>MEDLINE
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              Text: 2025 Mar 12
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