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Perturbation of Pseudomonas aeruginosa peptidoglycan recycling by anti-folates and design of a dual-action inhibitor.

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Title: Perturbation of Pseudomonas aeruginosa peptidoglycan recycling by anti-folates and design of a dual-action inhibitor.
Authors: Yaeger LN; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Sychantha D; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Luong P; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Shekarriz S; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Goncalves O; Département de Biologie, Université de Sherbrooke, Sherbrooke, Québec, Canada., Dobrin A; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Ranieri MR; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Lamers RP; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Harvey H; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., diCenzo GC; Department of Biology, Queen's University, Kingston, Ontario, Canada., Surette M; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Côté J-P; Département de Biologie, Université de Sherbrooke, Sherbrooke, Québec, Canada., Magolan J; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Burrows LL; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.
Source: MBio [mBio] 2025 Mar 12; Vol. 16 (3), pp. e0298424. Date of Electronic Publication: 2025 Jan 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE
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  Data: Perturbation of Pseudomonas aeruginosa peptidoglycan recycling by anti-folates and design of a dual-action inhibitor.
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  Data: <searchLink fieldCode="AU" term="%22Yaeger+LN%22">Yaeger LN</searchLink>; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Sychantha+D%22">Sychantha D</searchLink>; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Luong+P%22">Luong P</searchLink>; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Shekarriz+S%22">Shekarriz S</searchLink>; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Goncalves+O%22">Goncalves O</searchLink>; Département de Biologie, Université de Sherbrooke, Sherbrooke, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Dobrin+A%22">Dobrin A</searchLink>; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Ranieri+MR%22">Ranieri MR</searchLink>; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Lamers+RP%22">Lamers RP</searchLink>; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Harvey+H%22">Harvey H</searchLink>; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22diCenzo+GC%22">diCenzo GC</searchLink>; Department of Biology, Queen's University, Kingston, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Surette+M%22">Surette M</searchLink>; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Côté+J-P%22">Côté J-P</searchLink>; Département de Biologie, Université de Sherbrooke, Sherbrooke, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Magolan+J%22">Magolan J</searchLink>; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Burrows+LL%22">Burrows LL</searchLink>; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101519231%22">MBio</searchLink> [mBio] 2025 Mar 12; Vol. 16 (3), pp. e0298424. <i>Date of Electronic Publication: </i>2025 Jan 29.
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