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Sox2 interacts with Atoh1 and Huwe1 loci to regulate Atoh1 transcription and stability during hair cell differentiation.

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Title: Sox2 interacts with Atoh1 and Huwe1 loci to regulate Atoh1 transcription and stability during hair cell differentiation.
Authors: Cheng YF; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America.; Speech and Hearing Bioscience and Technology, Harvard Medical School, Boston, Massachusetts, United States of America., Kempfle JS; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America., Chiang H; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America., Tani K; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America., Wang Q; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America., Chen SH; Lab for Cell Dynamics, Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.; National Center for Theoretical Sciences, Physics Division, Taipei, Taiwan., Lenz D; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America., Chen WY; Institute of Biochemistry and Molecular Biology, National Yang Ming Chiao Tung University, Taipei, Taiwan., Wu W; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America., Petrillo M; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America., Edge ASB; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America.; Speech and Hearing Bioscience and Technology, Harvard Medical School, Boston, Massachusetts, United States of America.; Harvard Stem Cell Institute, Cambridge, Massachusetts, United States of America.
Source: PLoS genetics [PLoS Genet] 2025 Jan 30; Vol. 21 (1), pp. e1011573. Date of Electronic Publication: 2025 Jan 30 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Sox2 interacts with Atoh1 and Huwe1 loci to regulate Atoh1 transcription and stability during hair cell differentiation.
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  Data: <searchLink fieldCode="AU" term="%22Cheng+YF%22">Cheng YF</searchLink>; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America.; Speech and Hearing Bioscience and Technology, Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Kempfle+JS%22">Kempfle JS</searchLink>; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Chiang+H%22">Chiang H</searchLink>; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Tani+K%22">Tani K</searchLink>; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Chen+SH%22">Chen SH</searchLink>; Lab for Cell Dynamics, Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.; National Center for Theoretical Sciences, Physics Division, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lenz+D%22">Lenz D</searchLink>; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Chen+WY%22">Chen WY</searchLink>; Institute of Biochemistry and Molecular Biology, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+W%22">Wu W</searchLink>; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Petrillo+M%22">Petrillo M</searchLink>; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Edge+ASB%22">Edge ASB</searchLink>; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America.; Speech and Hearing Bioscience and Technology, Harvard Medical School, Boston, Massachusetts, United States of America.; Harvard Stem Cell Institute, Cambridge, Massachusetts, United States of America.
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