View in EDS HTML Full Text PDF Full Text

DNA-Dependent Protein Kinase Inhibitor Peposertib Enhances Efficacy of 177Lu-Based Radioimmunotherapy in Preclinical Models of Prostate and Renal Cell Carcinoma.

Saved in:
Bibliographic Details
Title: DNA-Dependent Protein Kinase Inhibitor Peposertib Enhances Efficacy of 177Lu-Based Radioimmunotherapy in Preclinical Models of Prostate and Renal Cell Carcinoma.
Authors: Johnstone CN; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.; Department of Clinical Pathology, University of Melbourne, Parkville, Victoria, Australia., Osellame LD; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia., Cao Z; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.; Department of Molecular Imaging and Therapy, Austin Health, Heidelberg, Victoria, Australia., McDonald AF; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.; Department of Molecular Imaging and Therapy, Austin Health, Heidelberg, Victoria, Australia., Rigopoulos A; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia., Burvenich IJG; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia., Wichmann CW; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.; Department of Molecular Imaging and Therapy, Austin Health, Heidelberg, Victoria, Australia., Guo N; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia., Ivashkevich AN; Telix Pharmaceuticals, North Melbourne, Victoria, Australia., Wheatcroft MP; Telix Pharmaceuticals, North Melbourne, Victoria, Australia., Yan EB; Telix Pharmaceuticals, North Melbourne, Victoria, Australia., Zimmermann A; Merck KGaA, Darmstadt, Germany., Zenke FT; EMD Serono, Billerica, Massachusetts; and., Sirrenberg C; Merck KGaA, Darmstadt, Germany., Scott FE; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia., Scott AM; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia; andrew.scott@onjcri.org.au.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.; Department of Molecular Imaging and Therapy, Austin Health, Heidelberg, Victoria, Australia.; Department of Medicine, University of Melbourne, Parkville, Victoria, Australia.
Source: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2025 Mar 03; Vol. 66 (3), pp. 385-390. Date of Electronic Publication: 2025 Mar 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 39884775
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: DNA-Dependent Protein Kinase Inhibitor Peposertib Enhances Efficacy of <superscript>177</superscript>Lu-Based Radioimmunotherapy in Preclinical Models of Prostate and Renal Cell Carcinoma.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Johnstone+CN%22">Johnstone CN</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.; Department of Clinical Pathology, University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Osellame+LD%22">Osellame LD</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Cao+Z%22">Cao Z</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.; Department of Molecular Imaging and Therapy, Austin Health, Heidelberg, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22McDonald+AF%22">McDonald AF</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.; Department of Molecular Imaging and Therapy, Austin Health, Heidelberg, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Rigopoulos+A%22">Rigopoulos A</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Burvenich+IJG%22">Burvenich IJG</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Wichmann+CW%22">Wichmann CW</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.; Department of Molecular Imaging and Therapy, Austin Health, Heidelberg, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Guo+N%22">Guo N</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Ivashkevich+AN%22">Ivashkevich AN</searchLink>; Telix Pharmaceuticals, North Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Wheatcroft+MP%22">Wheatcroft MP</searchLink>; Telix Pharmaceuticals, North Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Yan+EB%22">Yan EB</searchLink>; Telix Pharmaceuticals, North Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Zimmermann+A%22">Zimmermann A</searchLink>; Merck KGaA, Darmstadt, Germany.<br /><searchLink fieldCode="AU" term="%22Zenke+FT%22">Zenke FT</searchLink>; EMD Serono, Billerica, Massachusetts; and.<br /><searchLink fieldCode="AU" term="%22Sirrenberg+C%22">Sirrenberg C</searchLink>; Merck KGaA, Darmstadt, Germany.<br /><searchLink fieldCode="AU" term="%22Scott+FE%22">Scott FE</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Scott+AM%22">Scott AM</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia; andrew.scott@onjcri.org.au.; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.; Department of Molecular Imaging and Therapy, Austin Health, Heidelberg, Victoria, Australia.; Department of Medicine, University of Melbourne, Parkville, Victoria, Australia.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%220217410%22">Journal of nuclear medicine : official publication, Society of Nuclear Medicine</searchLink> [J Nucl Med] 2025 Mar 03; Vol. 66 (3), pp. 385-390. <i>Date of Electronic Publication: </i>2025 Mar 03.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Society+of+Nuclear+Medicine%22">Society of Nuclear Medicine </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0217410 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1535-5667 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201615505%22">01615505 </searchLink><i>NLM ISO Abbreviation: </i>J Nucl Med <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39884775
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.2967/jnumed.124.268695
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 385
    Titles:
      – TitleFull: DNA-Dependent Protein Kinase Inhibitor Peposertib Enhances Efficacy of 177Lu-Based Radioimmunotherapy in Preclinical Models of Prostate and Renal Cell Carcinoma.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Johnstone CN
      – PersonEntity:
          Name:
            NameFull: Osellame LD
      – PersonEntity:
          Name:
            NameFull: Cao Z
      – PersonEntity:
          Name:
            NameFull: McDonald AF
      – PersonEntity:
          Name:
            NameFull: Rigopoulos A
      – PersonEntity:
          Name:
            NameFull: Burvenich IJG
      – PersonEntity:
          Name:
            NameFull: Wichmann CW
      – PersonEntity:
          Name:
            NameFull: Guo N
      – PersonEntity:
          Name:
            NameFull: Ivashkevich AN
      – PersonEntity:
          Name:
            NameFull: Wheatcroft MP
      – PersonEntity:
          Name:
            NameFull: Yan EB
      – PersonEntity:
          Name:
            NameFull: Zimmermann A
      – PersonEntity:
          Name:
            NameFull: Zenke FT
      – PersonEntity:
          Name:
            NameFull: Sirrenberg C
      – PersonEntity:
          Name:
            NameFull: Scott FE
      – PersonEntity:
          Name:
            NameFull: Scott AM
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 03
              M: 03
              Text: 2025 Mar 03
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1535-5667
          Numbering:
            – Type: volume
              Value: 66
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
              Type: main
ResultId 1