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Identifying falsified COVID-19 vaccines by analysing vaccine vial label and excipient profiles using MALDI-ToF mass spectrometry.

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Title: Identifying falsified COVID-19 vaccines by analysing vaccine vial label and excipient profiles using MALDI-ToF mass spectrometry.
Authors: Arman BY; Department of Biochemistry, University of Oxford, OX1 3QU, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, OX1 3QU, Oxford, UK., Clarke R; Department of Chemistry, University of Oxford, OX1 3TA, Oxford, UK., Bharucha T; Department of Biochemistry, University of Oxford, OX1 3QU, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, OX1 3QU, Oxford, UK., Fernandez LG; Department of Biochemistry, University of Oxford, OX1 3QU, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, OX1 3QU, Oxford, UK., Walsby-Tickle J; Department of Chemistry, University of Oxford, OX1 3TA, Oxford, UK., Deats M; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.; Infectious Diseases Data Observatory, Centre of Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK., Mosca S; Central Laser Facility, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, UKRI, Harwell Campus, Oxford, OX11 0QX, UK., Lin Q; Central Laser Facility, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, UKRI, Harwell Campus, Oxford, OX11 0QX, UK.; Hybrid Materials for Opto-Electronics Group, Department of Molecules and Materials, MESA+ Institute for Nanotechnology, Molecules Center and Center for Brain-Inspired Nano Systems, Faculty of Science and Technology, University of Twente, 7500AE, Enschede, the Netherlands., Banerjee S; Central Laser Facility, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, UKRI, Harwell Campus, Oxford, OX11 0QX, UK., Chunekar SR; Serum Institute of India Pvt. Ltd., 212/2, Hadapsar, Pune, 411028, India., Patil KD; Serum Institute of India Pvt. Ltd., 212/2, Hadapsar, Pune, 411028, India., Gairola S; Serum Institute of India Pvt. Ltd., 212/2, Hadapsar, Pune, 411028, India., Dunachie S; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.; Department of Microbiology and Infectious Diseases, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 9DU, UK.; NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 9DU, UK., Merchant HA; Department of Bioscience, School of Health, Sport and Bioscience, University of East London, Water Lane, London, E15 4LZ, UK., Stokes R; Agilent Technologies LDA UK, Becquerel Avenue, Didcot, OX11 0RA, UK., Kuwana R; Regulation and Safety Unit, Regulation and Prequalification Department, Access to Medicines and Health Products Division, World Health Organization (WHO), Geneva, Switzerland., Maes A; Regulation and Safety Unit, Regulation and Prequalification Department, Access to Medicines and Health Products Division, World Health Organization (WHO), Geneva, Switzerland., Charrier JP; Department of Microbiology Research & Development, bioMérieux, Marcy l'Étoile, France., Probert F; Department of Chemistry, University of Oxford, OX1 3TA, Oxford, UK., Caillet C; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.; Infectious Diseases Data Observatory, Centre of Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK., Matousek P; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK.; Central Laser Facility, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, UKRI, Harwell Campus, Oxford, OX11 0QX, UK., McCullagh J; Department of Chemistry, University of Oxford, OX1 3TA, Oxford, UK., Newton PN; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK. paul.newton@ndm.ox.ac.uk.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand. paul.newton@ndm.ox.ac.uk.; Infectious Diseases Data Observatory, Centre of Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK. paul.newton@ndm.ox.ac.uk., Zitzmann N; Department of Biochemistry, University of Oxford, OX1 3QU, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, OX1 3QU, Oxford, UK., Gangadharan B; Department of Biochemistry, University of Oxford, OX1 3QU, Oxford, UK. bevin.gangadharan@bioch.ox.ac.uk.; Kavli Institute for Nanoscience Discovery, University of Oxford, OX1 3QU, Oxford, UK. bevin.gangadharan@bioch.ox.ac.uk.
Source: NPJ vaccines [NPJ Vaccines] 2025 Jan 30; Vol. 10 (1), pp. 19. Date of Electronic Publication: 2025 Jan 30.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature in partnership with the Sealy Center for Vaccine Development Country of Publication: England NLM ID: 101699863 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-0105 (Electronic) Linking ISSN: 20590105 NLM ISO Abbreviation: NPJ Vaccines Subsets: PubMed not MEDLINE
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  Data: Identifying falsified COVID-19 vaccines by analysing vaccine vial label and excipient profiles using MALDI-ToF mass spectrometry.
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  Data: <searchLink fieldCode="AU" term="%22Arman+BY%22">Arman BY</searchLink>; Department of Biochemistry, University of Oxford, OX1 3QU, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, OX1 3QU, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Clarke+R%22">Clarke R</searchLink>; Department of Chemistry, University of Oxford, OX1 3TA, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Bharucha+T%22">Bharucha T</searchLink>; Department of Biochemistry, University of Oxford, OX1 3QU, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, OX1 3QU, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Fernandez+LG%22">Fernandez LG</searchLink>; Department of Biochemistry, University of Oxford, OX1 3QU, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, OX1 3QU, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Walsby-Tickle+J%22">Walsby-Tickle J</searchLink>; Department of Chemistry, University of Oxford, OX1 3TA, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Deats+M%22">Deats M</searchLink>; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.; Infectious Diseases Data Observatory, Centre of Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK.<br /><searchLink fieldCode="AU" term="%22Mosca+S%22">Mosca S</searchLink>; Central Laser Facility, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, UKRI, Harwell Campus, Oxford, OX11 0QX, UK.<br /><searchLink fieldCode="AU" term="%22Lin+Q%22">Lin Q</searchLink>; Central Laser Facility, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, UKRI, Harwell Campus, Oxford, OX11 0QX, UK.; Hybrid Materials for Opto-Electronics Group, Department of Molecules and Materials, MESA+ Institute for Nanotechnology, Molecules Center and Center for Brain-Inspired Nano Systems, Faculty of Science and Technology, University of Twente, 7500AE, Enschede, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Banerjee+S%22">Banerjee S</searchLink>; Central Laser Facility, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, UKRI, Harwell Campus, Oxford, OX11 0QX, UK.<br /><searchLink fieldCode="AU" term="%22Chunekar+SR%22">Chunekar SR</searchLink>; Serum Institute of India Pvt. 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Ltd., 212/2, Hadapsar, Pune, 411028, India.<br /><searchLink fieldCode="AU" term="%22Dunachie+S%22">Dunachie S</searchLink>; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.; Department of Microbiology and Infectious Diseases, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 9DU, UK.; NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 9DU, UK.<br /><searchLink fieldCode="AU" term="%22Merchant+HA%22">Merchant HA</searchLink>; Department of Bioscience, School of Health, Sport and Bioscience, University of East London, Water Lane, London, E15 4LZ, UK.<br /><searchLink fieldCode="AU" term="%22Stokes+R%22">Stokes R</searchLink>; Agilent Technologies LDA UK, Becquerel Avenue, Didcot, OX11 0RA, UK.<br /><searchLink fieldCode="AU" term="%22Kuwana+R%22">Kuwana R</searchLink>; Regulation and Safety Unit, Regulation and Prequalification Department, Access to Medicines and Health Products Division, World Health Organization (WHO), Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Maes+A%22">Maes A</searchLink>; Regulation and Safety Unit, Regulation and Prequalification Department, Access to Medicines and Health Products Division, World Health Organization (WHO), Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Charrier+JP%22">Charrier JP</searchLink>; Department of Microbiology Research & Development, bioMérieux, Marcy l'Étoile, France.<br /><searchLink fieldCode="AU" term="%22Probert+F%22">Probert F</searchLink>; Department of Chemistry, University of Oxford, OX1 3TA, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Caillet+C%22">Caillet C</searchLink>; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.; Infectious Diseases Data Observatory, Centre of Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK.<br /><searchLink fieldCode="AU" term="%22Matousek+P%22">Matousek P</searchLink>; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK.; Central Laser Facility, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, UKRI, Harwell Campus, Oxford, OX11 0QX, UK.<br /><searchLink fieldCode="AU" term="%22McCullagh+J%22">McCullagh J</searchLink>; Department of Chemistry, University of Oxford, OX1 3TA, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Newton+PN%22">Newton PN</searchLink>; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK. paul.newton@ndm.ox.ac.uk.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand. paul.newton@ndm.ox.ac.uk.; Infectious Diseases Data Observatory, Centre of Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK. paul.newton@ndm.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Zitzmann+N%22">Zitzmann N</searchLink>; Department of Biochemistry, University of Oxford, OX1 3QU, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, OX1 3QU, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Gangadharan+B%22">Gangadharan B</searchLink>; Department of Biochemistry, University of Oxford, OX1 3QU, Oxford, UK. bevin.gangadharan@bioch.ox.ac.uk.; Kavli Institute for Nanoscience Discovery, University of Oxford, OX1 3QU, Oxford, UK. bevin.gangadharan@bioch.ox.ac.uk.
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