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De novo design of protein minibinder agonists of TLR3.

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Title: De novo design of protein minibinder agonists of TLR3.
Authors: Adams CS; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA., Kim H; Center for Biomolecular & Cellular Structure, Institute for Basic Science (IBS), Daejeon, 34126, South Korea., Burtner AE; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA., Lee DS; Center for Biomolecular & Cellular Structure, Institute for Basic Science (IBS), Daejeon, 34126, South Korea., Dobbins C; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA., Criswell C; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA., Coventry B; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA., Tran-Pearson A; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA., Kim HM; Center for Biomolecular & Cellular Structure, Institute for Basic Science (IBS), Daejeon, 34126, South Korea. hm_kim@kaist.ac.kr.; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, South Korea. hm_kim@kaist.ac.kr., King NP; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA. neilking@uw.edu.; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA. neilking@uw.edu.
Source: Nature communications [Nat Commun] 2025 Jan 31; Vol. 16 (1), pp. 1234. Date of Electronic Publication: 2025 Jan 31.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Adams+CS%22">Adams CS</searchLink>; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Kim+H%22">Kim H</searchLink>; Center for Biomolecular & Cellular Structure, Institute for Basic Science (IBS), Daejeon, 34126, South Korea.<br /><searchLink fieldCode="AU" term="%22Burtner+AE%22">Burtner AE</searchLink>; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Lee+DS%22">Lee DS</searchLink>; Center for Biomolecular & Cellular Structure, Institute for Basic Science (IBS), Daejeon, 34126, South Korea.<br /><searchLink fieldCode="AU" term="%22Dobbins+C%22">Dobbins C</searchLink>; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Criswell+C%22">Criswell C</searchLink>; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Coventry+B%22">Coventry B</searchLink>; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Tran-Pearson+A%22">Tran-Pearson A</searchLink>; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Kim+HM%22">Kim HM</searchLink>; Center for Biomolecular & Cellular Structure, Institute for Basic Science (IBS), Daejeon, 34126, South Korea. hm_kim@kaist.ac.kr.; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, South Korea. hm_kim@kaist.ac.kr.<br /><searchLink fieldCode="AU" term="%22King+NP%22">King NP</searchLink>; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA. neilking@uw.edu.; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA. neilking@uw.edu.
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