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Quantification of cinpanemab (BIIB054) binding to α-synuclein in cerebrospinal fluid of phase 1 single ascending dose samples.

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Title: Quantification of cinpanemab (BIIB054) binding to α-synuclein in cerebrospinal fluid of phase 1 single ascending dose samples.
Authors: Liu Y; Biogen, Cambridge, Massachusetts. Electronic address: christine.liu369@gmail.com., Yang M; Biogen, Cambridge, Massachusetts., Fraser K; Biogen, Cambridge, Massachusetts., Graham D; Biogen, Cambridge, Massachusetts., Weinreb PH; Biogen, Cambridge, Massachusetts., Weihofen A; Biogen, Cambridge, Massachusetts., Hirst WD; Biogen, Cambridge, Massachusetts., Cedarbaum JM; Biogen, Cambridge, Massachusetts., Pepinsky B; Biogen, Cambridge, Massachusetts.
Source: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2025 Jan; Vol. 392 (1), pp. 100003. Date of Electronic Publication: 2024 Nov 22.
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0376362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0103 (Electronic) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Quantification of cinpanemab (BIIB054) binding to α-synuclein in cerebrospinal fluid of phase 1 single ascending dose samples.
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  Data: <searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Biogen, Cambridge, Massachusetts. Electronic address: christine.liu369@gmail.com.<br /><searchLink fieldCode="AU" term="%22Yang+M%22">Yang M</searchLink>; Biogen, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Fraser+K%22">Fraser K</searchLink>; Biogen, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Graham+D%22">Graham D</searchLink>; Biogen, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Weinreb+PH%22">Weinreb PH</searchLink>; Biogen, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Weihofen+A%22">Weihofen A</searchLink>; Biogen, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Hirst+WD%22">Hirst WD</searchLink>; Biogen, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Cedarbaum+JM%22">Cedarbaum JM</searchLink>; Biogen, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Pepinsky+B%22">Pepinsky B</searchLink>; Biogen, Cambridge, Massachusetts.
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  Data: <searchLink fieldCode="JN" term="%220376362%22">The Journal of pharmacology and experimental therapeutics</searchLink> [J Pharmacol Exp Ther] 2025 Jan; Vol. 392 (1), pp. 100003. <i>Date of Electronic Publication: </i>2024 Nov 22.
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  Data: Journal Article; Clinical Trial, Phase I
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>0376362 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1521-0103 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200223565%22">00223565 </searchLink><i>NLM ISO Abbreviation: </i>J Pharmacol Exp Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1124/jpet.124.002199
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        Text: English
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      – TitleFull: Quantification of cinpanemab (BIIB054) binding to α-synuclein in cerebrospinal fluid of phase 1 single ascending dose samples.
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              Text: 2025 Jan
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              Y: 2025
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