Phase Ib Study of Immunocytokine Simlukafusp Alfa (FAP-IL2v) Combined with Pembrolizumab for Treatment of Advanced and/or Metastatic Melanoma.

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Title: Phase Ib Study of Immunocytokine Simlukafusp Alfa (FAP-IL2v) Combined with Pembrolizumab for Treatment of Advanced and/or Metastatic Melanoma.
Authors: Munoz-Couselo E; Vall d'Hebron University Hospital, VHIO, Vall d'Hebron Institute of Oncology, Barcelona, Spain., Soria Rivas A; Department of Medical Oncology, University Hospital Ramón y Cajal, Madrid, Spain., Sandhu S; Department of Medical Oncology, Peter MacCallum Cancer Centre and the University of Melbourne, Melbourne, Australia., Long GV; Melanoma Institute Australia, The University of Sydney, Sydney, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.; Department of Medical Oncology, Royal North Shore and Mater Hospitals, Sydney, Australia., Sanmamed MF; Department of Medical Oncology, Clinica Universidad de Navarra, Pamplona, Spain.; CIBERONC, Instituto de Salud Carlos III, Madrid, Spain., Spreafico A; Division of Medical Oncology, Princess Margaret Cancer Centre University Health Network, Toronto, Canada., Buchbinder E; Beth Israel Deaconess Medical Center, Boston, Massachusetts., Sznol M; Yale University School of Medicine, New Haven, Connecticut., Prenen H; Antwerp University Hospital, Edegem, Belgium., Fedenko A; P.A. Gertsen Moscow Oncology Research Institute, Moscow, Russia., Milhem M; University of Iowa, Iowa City, Iowa., Arance Fernandez AM; Department of Oncology, Hospital Clínic of Barcelona and IDIBAPS, Barcelona, Spain., Grob JJ; APHM and Aix-Marseille University, Marseille, France., Demidov L; N.N. Blokhin Russian Cancer Research Center, Moscow, Russia., Robert C; Institut Gustave Roussy and Paris Saclay University, Villejuif, France., Habigt C; Roche Pharma Research and Early Development, Early Clinical Development Oncology, Roche Innovation Center Munich, Munich, Germany., Evers S; Roche Pharma Research and Early Development, Early Clinical Development Oncology, Roche Innovation Center Basel, Basel, Switzerland., Sleiman N; Roche Pharma Research and Early Development, Early Clinical Development Oncology, Roche Innovation Center Basel, Basel, Switzerland., Dejardin D; Roche Pharma Research and Early Development, Early Clinical Development Oncology, Roche Innovation Center Basel, Basel, Switzerland., Ardeshir C; F. Hoffmann-La Roche Ltd, Welwyn Garden City, United Kingdom., Martin N; Roche Pharma Research and Early Development, Early Clinical Development Oncology, Roche Innovation Center Zurich, Schlieren, Switzerland., Boetsch C; Roche Pharma Research and Early Development, Early Clinical Development Oncology, Roche Innovation Center Basel, Basel, Switzerland., Charo J; Roche Pharma Research and Early Development, Early Clinical Development Oncology, Roche Innovation Center Zurich, Schlieren, Switzerland., Teichgräber V; Roche Pharma Research and Early Development, Early Clinical Development Oncology, Roche Innovation Center Basel, Basel, Switzerland., Kraxner A; Roche Pharma Research and Early Development, Early Clinical Development Oncology, Roche Innovation Center Basel, Basel, Switzerland., Keshelava N; Roche Pharma Research and Early Development, Early Clinical Development Oncology, Roche Innovation Center Zurich, Schlieren, Switzerland., Bechter O; Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium.
Source: Cancer research communications [Cancer Res Commun] 2025 Feb 01; Vol. 5 (2), pp. 358-368.
Publication Type: Journal Article; Clinical Trial, Phase I; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print Cited Medium: Internet ISSN: 2767-9764 (Electronic) Linking ISSN: 27679764 NLM ISO Abbreviation: Cancer Res Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2767-9764
DOI:10.1158/2767-9764.CRC-24-0601