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Clioquinol inhibits angiogenesis by promoting VEGFR2 degradation and synergizes with AKT inhibition to suppress triple-negative breast cancer vascularization.

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Title: Clioquinol inhibits angiogenesis by promoting VEGFR2 degradation and synergizes with AKT inhibition to suppress triple-negative breast cancer vascularization.
Authors: Gu Y; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saarland, Germany. yuan.gu@uks.eu., Tang T; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saarland, Germany., Qiu M; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saarland, Germany.; Department of Respiratory Oncology, Guangxi Medical University Cancer Hospital, Nanning, 530021, China., Wang H; Shaanxi University of Chinese Medicine, Shaanxi, 712046, China., Ampofo E; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saarland, Germany., Menger MD; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saarland, Germany., Laschke MW; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saarland, Germany.
Source: Angiogenesis [Angiogenesis] 2025 Feb 03; Vol. 28 (2), pp. 13. Date of Electronic Publication: 2025 Feb 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 9814575 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7209 (Electronic) Linking ISSN: 09696970 NLM ISO Abbreviation: Angiogenesis Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Clioquinol inhibits angiogenesis by promoting VEGFR2 degradation and synergizes with AKT inhibition to suppress triple-negative breast cancer vascularization.
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  Data: <searchLink fieldCode="AU" term="%22Gu+Y%22">Gu Y</searchLink>; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saarland, Germany. yuan.gu@uks.eu.<br /><searchLink fieldCode="AU" term="%22Tang+T%22">Tang T</searchLink>; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saarland, Germany.<br /><searchLink fieldCode="AU" term="%22Qiu+M%22">Qiu M</searchLink>; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saarland, Germany.; Department of Respiratory Oncology, Guangxi Medical University Cancer Hospital, Nanning, 530021, China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Shaanxi University of Chinese Medicine, Shaanxi, 712046, China.<br /><searchLink fieldCode="AU" term="%22Ampofo+E%22">Ampofo E</searchLink>; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saarland, Germany.<br /><searchLink fieldCode="AU" term="%22Menger+MD%22">Menger MD</searchLink>; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saarland, Germany.<br /><searchLink fieldCode="AU" term="%22Laschke+MW%22">Laschke MW</searchLink>; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saarland, Germany.
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  Data: <searchLink fieldCode="JN" term="%229814575%22">Angiogenesis</searchLink> [Angiogenesis] 2025 Feb 03; Vol. 28 (2), pp. 13. <i>Date of Electronic Publication: </i>2025 Feb 03.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>9814575 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-7209 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209696970%22">09696970 </searchLink><i>NLM ISO Abbreviation: </i>Angiogenesis <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1007/s10456-024-09965-1
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      – Code: eng
        Text: English
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        StartPage: 13
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      – TitleFull: Clioquinol inhibits angiogenesis by promoting VEGFR2 degradation and synergizes with AKT inhibition to suppress triple-negative breast cancer vascularization.
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              Text: 2025 Feb 03
              Type: published
              Y: 2025
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