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The KP.2-adapted COVID-19 vaccine improves neutralising activity against the XEC variant.

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Title: The KP.2-adapted COVID-19 vaccine improves neutralising activity against the XEC variant.
Authors: Suthar MS; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30329, USA; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA; Department of Microbiology and Immunology, Emory University, Atlanta, GA, USA. Electronic address: msuthar@emory.edu., Manning KE; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30329, USA; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA., Ellis ML; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30329, USA; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA., Jain S; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30329, USA; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA., Bechnak K; Hope Clinic of Emory Vaccine Center, Emory University, Decatur, GA, USA., Vander Velden J; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30329, USA; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA., Laboune F; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Henry AR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Godbole S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Kim S; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30329, USA; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA., Sahoo MK; Stanford University School of Medicine, Stanford, CA, USA., Paredes I; Hope Clinic of Emory Vaccine Center, Emory University, Decatur, GA, USA., Dib SM; Hope Clinic of Emory Vaccine Center, Emory University, Decatur, GA, USA., Kalash S; Hope Clinic of Emory Vaccine Center, Emory University, Decatur, GA, USA., Radi C; Hope Clinic of Emory Vaccine Center, Emory University, Decatur, GA, USA., Hicks H; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA., Tamin A; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA., Gardner M; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA., Bowen N; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA., Cook P; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA., Paden C; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA., Harcourt J; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA., Pinsky BA; Stanford University School of Medicine, Stanford, CA, USA., Douek DC; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Rouphael N; Hope Clinic of Emory Vaccine Center, Emory University, Decatur, GA, USA; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA., Moreno A; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA. Electronic address: camoren@emory.edu.
Source: The Lancet. Infectious diseases [Lancet Infect Dis] 2025 Mar; Vol. 25 (3), pp. e122-e123. Date of Electronic Publication: 2025 Jan 31.
Publication Type: Letter
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 101130150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-4457 (Electronic) Linking ISSN: 14733099 NLM ISO Abbreviation: Lancet Infect Dis Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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Items – Name: Title
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  Data: The KP.2-adapted COVID-19 vaccine improves neutralising activity against the XEC variant.
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  Data: <searchLink fieldCode="AU" term="%22Suthar+MS%22">Suthar MS</searchLink>; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30329, USA; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA; Department of Microbiology and Immunology, Emory University, Atlanta, GA, USA. Electronic address: msuthar@emory.edu.<br /><searchLink fieldCode="AU" term="%22Manning+KE%22">Manning KE</searchLink>; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30329, USA; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Ellis+ML%22">Ellis ML</searchLink>; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30329, USA; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Jain+S%22">Jain S</searchLink>; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30329, USA; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Bechnak+K%22">Bechnak K</searchLink>; Hope Clinic of Emory Vaccine Center, Emory University, Decatur, GA, USA.<br /><searchLink fieldCode="AU" term="%22Vander+Velden+J%22">Vander Velden J</searchLink>; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30329, USA; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Laboune+F%22">Laboune F</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Henry+AR%22">Henry AR</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Godbole+S%22">Godbole S</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30329, USA; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Sahoo+MK%22">Sahoo MK</searchLink>; Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Paredes+I%22">Paredes I</searchLink>; Hope Clinic of Emory Vaccine Center, Emory University, Decatur, GA, USA.<br /><searchLink fieldCode="AU" term="%22Dib+SM%22">Dib SM</searchLink>; Hope Clinic of Emory Vaccine Center, Emory University, Decatur, GA, USA.<br /><searchLink fieldCode="AU" term="%22Kalash+S%22">Kalash S</searchLink>; Hope Clinic of Emory Vaccine Center, Emory University, Decatur, GA, USA.<br /><searchLink fieldCode="AU" term="%22Radi+C%22">Radi C</searchLink>; Hope Clinic of Emory Vaccine Center, Emory University, Decatur, GA, USA.<br /><searchLink fieldCode="AU" term="%22Hicks+H%22">Hicks H</searchLink>; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Tamin+A%22">Tamin A</searchLink>; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Gardner+M%22">Gardner M</searchLink>; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Bowen+N%22">Bowen N</searchLink>; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Cook+P%22">Cook P</searchLink>; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Paden+C%22">Paden C</searchLink>; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Harcourt+J%22">Harcourt J</searchLink>; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Pinsky+BA%22">Pinsky BA</searchLink>; Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Douek+DC%22">Douek DC</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Rouphael+N%22">Rouphael N</searchLink>; Hope Clinic of Emory Vaccine Center, Emory University, Decatur, GA, USA; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Moreno+A%22">Moreno A</searchLink>; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA. Electronic address: camoren@emory.edu.
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  Data: <searchLink fieldCode="JN" term="%22101130150%22">The Lancet. Infectious diseases</searchLink> [Lancet Infect Dis] 2025 Mar; Vol. 25 (3), pp. e122-e123. <i>Date of Electronic Publication: </i>2025 Jan 31.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101130150 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-4457 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214733099%22">14733099 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Infect Dis <i>Subsets: </i>MEDLINE; In Process
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