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Plant-nanoparticles enhance anti-PD-L1 efficacy by shaping human commensal microbiota metabolites.

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Title: Plant-nanoparticles enhance anti-PD-L1 efficacy by shaping human commensal microbiota metabolites.
Authors: Teng Y; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA. yun.teng@louisville.edu., Luo C; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.; Department of Central Laboratory, The affiliated Huai'an First People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China., Qiu X; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.; Department of Breast and Thyroid Surgery, The affiliated Huai'an First People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China., Mu J; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA., Sriwastva MK; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA., Xu Q; Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA., Liu M; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.; Department of Breast and Thyroid Surgery, The affiliated Huai'an First People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China., Hu X; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Xu F; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA., Zhang L; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA., Park JW; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.; Department of Bioinformatics and Biostatistics, SPHIS, University of Louisville, Louisville, KY, USA., Hwang JY; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA., Kong M; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.; Department of Bioinformatics and Biostatistics, SPHIS, University of Louisville, Louisville, KY, USA., Liu Z; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA., Zhang X; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY, USA., Xu R; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY, USA., Yan J; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA., Merchant ML; Kidney Disease Program and Clinical Proteomics Center, University of Louisville, Louisville, KY, USA., McClain CJ; Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Louisville School of Medicine, Louisville, KY, USA., Zhang HG; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA. h0zhan17@louisville.edu.; Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA. h0zhan17@louisville.edu.; Robley Rex Veterans Affairs Medical Center, Louisville, KY, USA. h0zhan17@louisville.edu.
Source: Nature communications [Nat Commun] 2025 Feb 03; Vol. 16 (1), pp. 1295. Date of Electronic Publication: 2025 Feb 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Plant-nanoparticles enhance anti-PD-L1 efficacy by shaping human commensal microbiota metabolites.
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  Data: <searchLink fieldCode="AU" term="%22Teng+Y%22">Teng Y</searchLink>; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA. yun.teng@louisville.edu.<br /><searchLink fieldCode="AU" term="%22Luo+C%22">Luo C</searchLink>; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.; Department of Central Laboratory, The affiliated Huai'an First People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Qiu+X%22">Qiu X</searchLink>; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.; Department of Breast and Thyroid Surgery, The affiliated Huai'an First People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Mu+J%22">Mu J</searchLink>; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.<br /><searchLink fieldCode="AU" term="%22Sriwastva+MK%22">Sriwastva MK</searchLink>; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.<br /><searchLink fieldCode="AU" term="%22Xu+Q%22">Xu Q</searchLink>; Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA.<br /><searchLink fieldCode="AU" term="%22Liu+M%22">Liu M</searchLink>; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.; Department of Breast and Thyroid Surgery, The affiliated Huai'an First People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Hu+X%22">Hu X</searchLink>; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Xu+F%22">Xu F</searchLink>; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.<br /><searchLink fieldCode="AU" term="%22Park+JW%22">Park JW</searchLink>; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.; Department of Bioinformatics and Biostatistics, SPHIS, University of Louisville, Louisville, KY, USA.<br /><searchLink fieldCode="AU" term="%22Hwang+JY%22">Hwang JY</searchLink>; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.<br /><searchLink fieldCode="AU" term="%22Kong+M%22">Kong M</searchLink>; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.; Department of Bioinformatics and Biostatistics, SPHIS, University of Louisville, Louisville, KY, USA.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY, USA.<br /><searchLink fieldCode="AU" term="%22Xu+R%22">Xu R</searchLink>; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY, USA.<br /><searchLink fieldCode="AU" term="%22Yan+J%22">Yan J</searchLink>; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA.<br /><searchLink fieldCode="AU" term="%22Merchant+ML%22">Merchant ML</searchLink>; Kidney Disease Program and Clinical Proteomics Center, University of Louisville, Louisville, KY, USA.<br /><searchLink fieldCode="AU" term="%22McClain+CJ%22">McClain CJ</searchLink>; Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Louisville School of Medicine, Louisville, KY, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+HG%22">Zhang HG</searchLink>; Brown Cancer Center, University of Louisville School of Medicine, Louisville, USA. h0zhan17@louisville.edu.; Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA. h0zhan17@louisville.edu.; Robley Rex Veterans Affairs Medical Center, Louisville, KY, USA. h0zhan17@louisville.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Feb 03; Vol. 16 (1), pp. 1295. <i>Date of Electronic Publication: </i>2025 Feb 03.
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