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Stroma gene signature predicts responsiveness to chemotherapy in pancreatic ductal adenocarcinoma patient-derived xenograft models.

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Title: Stroma gene signature predicts responsiveness to chemotherapy in pancreatic ductal adenocarcinoma patient-derived xenograft models.
Authors: Anastasia A; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Formenti L; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Ostano P; Lab of Cancer Genomics, Fondazione 'Edo ed Elvo Tempia', Biella, Italy., Minoli L; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy.; Department of Veterinary Medicine and Animal Sciences (DIVAS), University of Milan (Unimi), Lodi, Italy., Resovi A; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Morosi L; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Fioravanti C; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Micotti E; Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Matteo C; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Scanziani E; Mouse and Animal Pathology Laboratory (MAPLab), Fondazione Unimi, Milan, Italy., Chiorino G; Lab of Cancer Genomics, Fondazione 'Edo ed Elvo Tempia', Biella, Italy., Giavazzi R; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Ghilardi C; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Belotti D; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy.
Source: Molecular oncology [Mol Oncol] 2025 Apr; Vol. 19 (4), pp. 1075-1091. Date of Electronic Publication: 2025 Feb 04.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Stroma gene signature predicts responsiveness to chemotherapy in pancreatic ductal adenocarcinoma patient-derived xenograft models.
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  Data: <searchLink fieldCode="AU" term="%22Anastasia+A%22">Anastasia A</searchLink>; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Formenti+L%22">Formenti L</searchLink>; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ostano+P%22">Ostano P</searchLink>; Lab of Cancer Genomics, Fondazione 'Edo ed Elvo Tempia', Biella, Italy.<br /><searchLink fieldCode="AU" term="%22Minoli+L%22">Minoli L</searchLink>; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy.; Department of Veterinary Medicine and Animal Sciences (DIVAS), University of Milan (Unimi), Lodi, Italy.<br /><searchLink fieldCode="AU" term="%22Resovi+A%22">Resovi A</searchLink>; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Morosi+L%22">Morosi L</searchLink>; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Fioravanti+C%22">Fioravanti C</searchLink>; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Micotti+E%22">Micotti E</searchLink>; Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Matteo+C%22">Matteo C</searchLink>; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Scanziani+E%22">Scanziani E</searchLink>; Mouse and Animal Pathology Laboratory (MAPLab), Fondazione Unimi, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Chiorino+G%22">Chiorino G</searchLink>; Lab of Cancer Genomics, Fondazione 'Edo ed Elvo Tempia', Biella, Italy.<br /><searchLink fieldCode="AU" term="%22Giavazzi+R%22">Giavazzi R</searchLink>; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ghilardi+C%22">Ghilardi C</searchLink>; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Belotti+D%22">Belotti D</searchLink>; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101308230%22">Molecular oncology</searchLink> [Mol Oncol] 2025 Apr; Vol. 19 (4), pp. 1075-1091. <i>Date of Electronic Publication: </i>2025 Feb 04.
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