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Activation-induced thrombospondin-4 works with thrombospondin-1 to build cytotoxic supramolecular attack particles.

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Title: Activation-induced thrombospondin-4 works with thrombospondin-1 to build cytotoxic supramolecular attack particles.
Authors: Cassioli C; Department of Life Sciences, University of Siena, Siena 53100, Italy., Capitani N; Department of Life Sciences, University of Siena, Siena 53100, Italy., Staton CC; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7FY, United Kingdom.; Institute for Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford OX3 7TY, United Kingdom., Schirra C; Department of Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine, Saarland University, Homburg 66421, Germany., Finetti F; Department of Life Sciences, University of Siena, Siena 53100, Italy., Onnis A; Department of Life Sciences, University of Siena, Siena 53100, Italy., Alawar N; Department of Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine, Saarland University, Homburg 66421, Germany., Tu SM; Department of Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine, Saarland University, Homburg 66421, Germany., Lopresti L; Department of Life Sciences, University of Siena, Siena 53100, Italy., Tatangelo V; Department of Life Sciences, University of Siena, Siena 53100, Italy., Tangredi C; Department of Life Sciences, University of Siena, Siena 53100, Italy., Valvo S; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7FY, United Kingdom., Chang HF; Department of Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine, Saarland University, Homburg 66421, Germany., Miccoli A; Department of Life Sciences, University of Siena, Siena 53100, Italy., Compeer EB; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7FY, United Kingdom., Nicholls J; Department of Pediatrics, Division of Blood & Marrow Transplant & Cellular Therapy, University of Minnesota, Minneapolis, MN 55455., Blazar BR; Department of Pediatrics, Division of Blood & Marrow Transplant & Cellular Therapy, University of Minnesota, Minneapolis, MN 55455., Marotta G; Stem Cell Transplant and Cellular Therapy Unit, Siena University Hospital, Siena 53100, Italy., Wood MJA; Institute for Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford OX3 7TY, United Kingdom., Trentin L; Hematology Unit, Department of Medicine, University of Padua, Padua 35128, Italy., Patrussi L; Department of Life Sciences, University of Siena, Siena 53100, Italy., Dustin ML; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7FY, United Kingdom., Becherer U; Department of Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine, Saarland University, Homburg 66421, Germany., Baldari CT; Department of Life Sciences, University of Siena, Siena 53100, Italy.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Feb 11; Vol. 122 (6), pp. e2413866122. Date of Electronic Publication: 2025 Feb 04.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: Activation-induced thrombospondin-4 works with thrombospondin-1 to build cytotoxic supramolecular attack particles.
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  Data: <searchLink fieldCode="AU" term="%22Cassioli+C%22">Cassioli C</searchLink>; Department of Life Sciences, University of Siena, Siena 53100, Italy.<br /><searchLink fieldCode="AU" term="%22Capitani+N%22">Capitani N</searchLink>; Department of Life Sciences, University of Siena, Siena 53100, Italy.<br /><searchLink fieldCode="AU" term="%22Staton+CC%22">Staton CC</searchLink>; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7FY, United Kingdom.; Institute for Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford OX3 7TY, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Schirra+C%22">Schirra C</searchLink>; Department of Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine, Saarland University, Homburg 66421, Germany.<br /><searchLink fieldCode="AU" term="%22Finetti+F%22">Finetti F</searchLink>; Department of Life Sciences, University of Siena, Siena 53100, Italy.<br /><searchLink fieldCode="AU" term="%22Onnis+A%22">Onnis A</searchLink>; Department of Life Sciences, University of Siena, Siena 53100, Italy.<br /><searchLink fieldCode="AU" term="%22Alawar+N%22">Alawar N</searchLink>; Department of Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine, Saarland University, Homburg 66421, Germany.<br /><searchLink fieldCode="AU" term="%22Tu+SM%22">Tu SM</searchLink>; Department of Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine, Saarland University, Homburg 66421, Germany.<br /><searchLink fieldCode="AU" term="%22Lopresti+L%22">Lopresti L</searchLink>; Department of Life Sciences, University of Siena, Siena 53100, Italy.<br /><searchLink fieldCode="AU" term="%22Tatangelo+V%22">Tatangelo V</searchLink>; Department of Life Sciences, University of Siena, Siena 53100, Italy.<br /><searchLink fieldCode="AU" term="%22Tangredi+C%22">Tangredi C</searchLink>; Department of Life Sciences, University of Siena, Siena 53100, Italy.<br /><searchLink fieldCode="AU" term="%22Valvo+S%22">Valvo S</searchLink>; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7FY, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Chang+HF%22">Chang HF</searchLink>; Department of Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine, Saarland University, Homburg 66421, Germany.<br /><searchLink fieldCode="AU" term="%22Miccoli+A%22">Miccoli A</searchLink>; Department of Life Sciences, University of Siena, Siena 53100, Italy.<br /><searchLink fieldCode="AU" term="%22Compeer+EB%22">Compeer EB</searchLink>; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7FY, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Nicholls+J%22">Nicholls J</searchLink>; Department of Pediatrics, Division of Blood & Marrow Transplant & Cellular Therapy, University of Minnesota, Minneapolis, MN 55455.<br /><searchLink fieldCode="AU" term="%22Blazar+BR%22">Blazar BR</searchLink>; Department of Pediatrics, Division of Blood & Marrow Transplant & Cellular Therapy, University of Minnesota, Minneapolis, MN 55455.<br /><searchLink fieldCode="AU" term="%22Marotta+G%22">Marotta G</searchLink>; Stem Cell Transplant and Cellular Therapy Unit, Siena University Hospital, Siena 53100, Italy.<br /><searchLink fieldCode="AU" term="%22Wood+MJA%22">Wood MJA</searchLink>; Institute for Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford OX3 7TY, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Trentin+L%22">Trentin L</searchLink>; Hematology Unit, Department of Medicine, University of Padua, Padua 35128, Italy.<br /><searchLink fieldCode="AU" term="%22Patrussi+L%22">Patrussi L</searchLink>; Department of Life Sciences, University of Siena, Siena 53100, Italy.<br /><searchLink fieldCode="AU" term="%22Dustin+ML%22">Dustin ML</searchLink>; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7FY, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Becherer+U%22">Becherer U</searchLink>; Department of Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine, Saarland University, Homburg 66421, Germany.<br /><searchLink fieldCode="AU" term="%22Baldari+CT%22">Baldari CT</searchLink>; Department of Life Sciences, University of Siena, Siena 53100, Italy.
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