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ROCK1 promotes B cell differentiation and proteostasis under stress through the heme-regulated proteins, BACH2 and HRI.

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Title: ROCK1 promotes B cell differentiation and proteostasis under stress through the heme-regulated proteins, BACH2 and HRI.
Authors: Rivera-Correa J; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA.; Biological Sciences Department, New York City College of Technology, City University of New York, Brooklyn, New York, USA., Gupta S; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA., Ricker E; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA., Flores-Castro D; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA., Jenkins D; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA., Vulcano S; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA., Phalke SP; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA., Pannellini T; Research Division and Precision Medicine Laboratory, Hospital for Special Surgery, New York, New York, USA., Miele MM; Microchemistry & Proteomics Core at Memorial Sloan Kettering Cancer Center, New York, New York, USA., Li Z; Microchemistry & Proteomics Core at Memorial Sloan Kettering Cancer Center, New York, New York, USA., Zamponi N; Hematology and Oncology Division, Weill Cornell Medicine, New York, New York, USA., Kim YB; Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA., Chinenov Y; David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, New York, USA., Giannopoulou E; Biological Sciences Department, New York City College of Technology, City University of New York, Brooklyn, New York, USA.; David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, New York, USA., Cerchietti L; Hematology and Oncology Division, Weill Cornell Medicine, New York, New York, USA., Pernis AB; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA.; David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, New York, USA.; Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
Source: JCI insight [JCI Insight] 2025 Feb 04; Vol. 10 (5). Date of Electronic Publication: 2025 Feb 04.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: ROCK1 promotes B cell differentiation and proteostasis under stress through the heme-regulated proteins, BACH2 and HRI.
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  Data: <searchLink fieldCode="AU" term="%22Rivera-Correa+J%22">Rivera-Correa J</searchLink>; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA.; Biological Sciences Department, New York City College of Technology, City University of New York, Brooklyn, New York, USA.<br /><searchLink fieldCode="AU" term="%22Gupta+S%22">Gupta S</searchLink>; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Ricker+E%22">Ricker E</searchLink>; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Flores-Castro+D%22">Flores-Castro D</searchLink>; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Jenkins+D%22">Jenkins D</searchLink>; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Vulcano+S%22">Vulcano S</searchLink>; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Phalke+SP%22">Phalke SP</searchLink>; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Pannellini+T%22">Pannellini T</searchLink>; Research Division and Precision Medicine Laboratory, Hospital for Special Surgery, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Miele+MM%22">Miele MM</searchLink>; Microchemistry & Proteomics Core at Memorial Sloan Kettering Cancer Center, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Microchemistry & Proteomics Core at Memorial Sloan Kettering Cancer Center, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Zamponi+N%22">Zamponi N</searchLink>; Hematology and Oncology Division, Weill Cornell Medicine, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Kim+YB%22">Kim YB</searchLink>; Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Chinenov+Y%22">Chinenov Y</searchLink>; David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Giannopoulou+E%22">Giannopoulou E</searchLink>; Biological Sciences Department, New York City College of Technology, City University of New York, Brooklyn, New York, USA.; David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Cerchietti+L%22">Cerchietti L</searchLink>; Hematology and Oncology Division, Weill Cornell Medicine, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Pernis+AB%22">Pernis AB</searchLink>; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA.; David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, New York, USA.; Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
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