Increased NFAT and NFκB signalling contribute to the hyperinflammatory phenotype in response to Aspergillus fumigatus in a mouse model of cystic fibrosis.

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Title: Increased NFAT and NFκB signalling contribute to the hyperinflammatory phenotype in response to Aspergillus fumigatus in a mouse model of cystic fibrosis.
Authors: Bercusson A; Department of Infectious Disease, Faculty of Medicine, Imperial College, London, United Kingdom.; Cystic Fibrosis Unit, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom., Williams TJ; Department of Infectious Disease, Faculty of Medicine, Imperial College, London, United Kingdom.; Department of Cardiothoracic Transplantation and Mechanical Support, Harefield Hospital, Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom., Simmonds NJ; Adult Cystic Fibrosis Centre, Royal Brompton Hospital, London, United Kingdom.; National Heart and Lung Institute, Imperial College, London, United Kingdom., Alton EW; National Heart and Lung Institute, Imperial College, London, United Kingdom., Griesenbach U; National Heart and Lung Institute, Imperial College, London, United Kingdom., Shah A; Department of Infectious Disease, Faculty of Medicine, Imperial College, London, United Kingdom.; Department of Respiratory Medicine, Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom., Warris A; Medical Research Council Centre for Medical Mycology, University of Exeter, Exeter, United Kingdom., Armstrong-James D; Department of Infectious Disease, Faculty of Medicine, Imperial College, London, United Kingdom.; Department of Respiratory Medicine, Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom.
Source: PLoS pathogens [PLoS Pathog] 2025 Feb 04; Vol. 21 (2), pp. e1012784. Date of Electronic Publication: 2025 Feb 04 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
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  Data: Increased NFAT and NFκB signalling contribute to the hyperinflammatory phenotype in response to Aspergillus fumigatus in a mouse model of cystic fibrosis.
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  Data: <searchLink fieldCode="AU" term="%22Bercusson+A%22">Bercusson A</searchLink>; Department of Infectious Disease, Faculty of Medicine, Imperial College, London, United Kingdom.; Cystic Fibrosis Unit, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Williams+TJ%22">Williams TJ</searchLink>; Department of Infectious Disease, Faculty of Medicine, Imperial College, London, United Kingdom.; Department of Cardiothoracic Transplantation and Mechanical Support, Harefield Hospital, Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Simmonds+NJ%22">Simmonds NJ</searchLink>; Adult Cystic Fibrosis Centre, Royal Brompton Hospital, London, United Kingdom.; National Heart and Lung Institute, Imperial College, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Alton+EW%22">Alton EW</searchLink>; National Heart and Lung Institute, Imperial College, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Griesenbach+U%22">Griesenbach U</searchLink>; National Heart and Lung Institute, Imperial College, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Shah+A%22">Shah A</searchLink>; Department of Infectious Disease, Faculty of Medicine, Imperial College, London, United Kingdom.; Department of Respiratory Medicine, Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Warris+A%22">Warris A</searchLink>; Medical Research Council Centre for Medical Mycology, University of Exeter, Exeter, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Armstrong-James+D%22">Armstrong-James D</searchLink>; Department of Infectious Disease, Faculty of Medicine, Imperial College, London, United Kingdom.; Department of Respiratory Medicine, Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom.
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              Text: 2025 Feb 04
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