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Implantation of engineered adipocytes suppresses tumor progression in cancer models.

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Title: Implantation of engineered adipocytes suppresses tumor progression in cancer models.
Authors: Nguyen HP; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA.; Department of Nutritional Sciences, University of Texas at Austin, Austin, TX, USA., An K; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Ito Y; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Kharbikar BN; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA., Sheng R; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Paredes B; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Murray E; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Pham K; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Bruck M; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Zhou X; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Biellak C; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Ushiki A; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Nobuhara M; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Fong SL; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Bernards DA; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA., Lynce F; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Dillon DA; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Magbanua MJM; Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA., Huppert LA; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Hammerlindl H; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA., Klein JA; Department of Nutritional Sciences, University of Texas at Austin, Austin, TX, USA., Valdiviez L; University of California Davis West Coast Metabolomics Center, Davis, CA, USA., Fiehn O; University of California Davis West Coast Metabolomics Center, Davis, CA, USA., Esserman L; Department of Surgery, University of California San Francisco, San Francisco, CA, USA., Desai TA; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; School of Engineering, Brown University, Providence, RI, USA., Yee SW; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA., Rosenbluth JM; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA., Ahituv N; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA. nadav.ahituv@ucsf.edu.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA. nadav.ahituv@ucsf.edu.
Source: Nature biotechnology [Nat Biotechnol] 2025 Dec; Vol. 43 (12), pp. 1979-1995. Date of Electronic Publication: 2025 Feb 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE
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  Data: Implantation of engineered adipocytes suppresses tumor progression in cancer models.
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  Data: <searchLink fieldCode="AU" term="%22Nguyen+HP%22">Nguyen HP</searchLink>; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA.; Department of Nutritional Sciences, University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22An+K%22">An K</searchLink>; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ito+Y%22">Ito Y</searchLink>; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kharbikar+BN%22">Kharbikar BN</searchLink>; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sheng+R%22">Sheng R</searchLink>; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Paredes+B%22">Paredes B</searchLink>; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Murray+E%22">Murray E</searchLink>; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pham+K%22">Pham K</searchLink>; 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Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Dillon+DA%22">Dillon DA</searchLink>; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Magbanua+MJM%22">Magbanua MJM</searchLink>; Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Huppert+LA%22">Huppert LA</searchLink>; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hammerlindl+H%22">Hammerlindl H</searchLink>; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Klein+JA%22">Klein JA</searchLink>; Department of Nutritional Sciences, University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Valdiviez+L%22">Valdiviez L</searchLink>; 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  Data: <searchLink fieldCode="JN" term="%229604648%22">Nature biotechnology</searchLink> [Nat Biotechnol] 2025 Dec; Vol. 43 (12), pp. 1979-1995. <i>Date of Electronic Publication: </i>2025 Feb 04.
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