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Anaemia predicts iron homoeostasis dysregulation and modulates the response to empagliflozin in heart failure with reduced ejection fraction: the EMPATROPISM-FE trial.

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Title: Anaemia predicts iron homoeostasis dysregulation and modulates the response to empagliflozin in heart failure with reduced ejection fraction: the EMPATROPISM-FE trial.
Authors: Angermann CE; Comprehensive Heart Failure Center Würzburg, University and University Hospital Würzburg, Am Schwarzenberg 15, 97078 Würzburg, Germany.; Department of Medicine 1, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080 Würzburg, Germany., Sehner S; Institute of Medical Biometry and Epidemiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Gerhardt LMS; Fifth Department of Medicine, University Medical Center Mannheim, Faculty of Medicine Mannheim of the University of Heidelberg, Mannheim, Germany., Santos-Gallego CG; Icahn School of Medicine at Mount Sinai, Cardiovascular Institute, New York, NY, USA., Requena-Ibanez JA; Icahn School of Medicine at Mount Sinai, Cardiovascular Institute, New York, NY, USA., Zeller T; University Center of Cardiovascular Science, University Heart and Vascular Center, University Hospital Hamburg-Eppendorf, and German Center of Cardiovascular Research, Partner Site Hamburg-Kiel-Lübeck, Hamburg, Germany., Maack C; Comprehensive Heart Failure Center Würzburg, University and University Hospital Würzburg, Am Schwarzenberg 15, 97078 Würzburg, Germany., Sanz J; Icahn School of Medicine at Mount Sinai, Cardiovascular Institute, New York, NY, USA., Frantz S; Comprehensive Heart Failure Center Würzburg, University and University Hospital Würzburg, Am Schwarzenberg 15, 97078 Würzburg, Germany.; Department of Medicine 1, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080 Würzburg, Germany., Ertl G; Comprehensive Heart Failure Center Würzburg, University and University Hospital Würzburg, Am Schwarzenberg 15, 97078 Würzburg, Germany.; Department of Medicine 1, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080 Würzburg, Germany., Badimon JJ; Icahn School of Medicine at Mount Sinai, Cardiovascular Institute, New York, NY, USA.
Source: European heart journal [Eur Heart J] 2025 Apr 22; Vol. 46 (16), pp. 1507-1523.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8006263 Publication Model: Print Cited Medium: Internet ISSN: 1522-9645 (Electronic) Linking ISSN: 0195668X NLM ISO Abbreviation: Eur Heart J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Anaemia predicts iron homoeostasis dysregulation and modulates the response to empagliflozin in heart failure with reduced ejection fraction: the EMPATROPISM-FE trial.
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  Data: <searchLink fieldCode="AU" term="%22Angermann+CE%22">Angermann CE</searchLink>; Comprehensive Heart Failure Center Würzburg, University and University Hospital Würzburg, Am Schwarzenberg 15, 97078 Würzburg, Germany.; Department of Medicine 1, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Sehner+S%22">Sehner S</searchLink>; Institute of Medical Biometry and Epidemiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gerhardt+LMS%22">Gerhardt LMS</searchLink>; Fifth Department of Medicine, University Medical Center Mannheim, Faculty of Medicine Mannheim of the University of Heidelberg, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Santos-Gallego+CG%22">Santos-Gallego CG</searchLink>; Icahn School of Medicine at Mount Sinai, Cardiovascular Institute, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Requena-Ibanez+JA%22">Requena-Ibanez JA</searchLink>; Icahn School of Medicine at Mount Sinai, Cardiovascular Institute, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Zeller+T%22">Zeller T</searchLink>; University Center of Cardiovascular Science, University Heart and Vascular Center, University Hospital Hamburg-Eppendorf, and German Center of Cardiovascular Research, Partner Site Hamburg-Kiel-Lübeck, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Maack+C%22">Maack C</searchLink>; Comprehensive Heart Failure Center Würzburg, University and University Hospital Würzburg, Am Schwarzenberg 15, 97078 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Sanz+J%22">Sanz J</searchLink>; Icahn School of Medicine at Mount Sinai, Cardiovascular Institute, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Frantz+S%22">Frantz S</searchLink>; Comprehensive Heart Failure Center Würzburg, University and University Hospital Würzburg, Am Schwarzenberg 15, 97078 Würzburg, Germany.; Department of Medicine 1, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ertl+G%22">Ertl G</searchLink>; Comprehensive Heart Failure Center Würzburg, University and University Hospital Würzburg, Am Schwarzenberg 15, 97078 Würzburg, Germany.; Department of Medicine 1, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Badimon+JJ%22">Badimon JJ</searchLink>; Icahn School of Medicine at Mount Sinai, Cardiovascular Institute, New York, NY, USA.
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              Text: 2025 Apr 22
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