Integrated In-silico and In-vivo Assessments of Betaine's Effect on the Hypothalamic-Pituitary-Testicular (HPT) Axis in Fluoride-Treated Rats.

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Title: Integrated In-silico and In-vivo Assessments of Betaine's Effect on the Hypothalamic-Pituitary-Testicular (HPT) Axis in Fluoride-Treated Rats.
Authors: Owumi S; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, ChangeLab-Changing Lives; Rm NB 302, Ibadan, Oyo State, 200005, Nigeria. zicri@hotmail.com., Oluwawibe BJ; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, ChangeLab-Changing Lives; Rm NB 302, Ibadan, Oyo State, 200005, Nigeria., Agbarogi H; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, ChangeLab-Changing Lives; Rm NB 302, Ibadan, Oyo State, 200005, Nigeria., Otunla MT; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, ChangeLab-Changing Lives; Rm NB 302, Ibadan, Oyo State, 200005, Nigeria., Owoeye O; Department of Anatomy, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Oyo State, Nigeria., Arunsi UO; School of Chemistry & Biochemistry, Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, 30332-0400, USA.
Source: Biological trace element research [Biol Trace Elem Res] 2025 Sep; Vol. 203 (9), pp. 4671-4693. Date of Electronic Publication: 2025 Feb 05.
Publication Type: Journal Article
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 7911509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-0720 (Electronic) Linking ISSN: 01634984 NLM ISO Abbreviation: Biol Trace Elem Res Subsets: MEDLINE
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  Data: Integrated In-silico and In-vivo Assessments of Betaine's Effect on the Hypothalamic-Pituitary-Testicular (HPT) Axis in Fluoride-Treated Rats.
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  Data: <searchLink fieldCode="AU" term="%22Owumi+S%22">Owumi S</searchLink>; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, ChangeLab-Changing Lives; Rm NB 302, Ibadan, Oyo State, 200005, Nigeria. zicri@hotmail.com.<br /><searchLink fieldCode="AU" term="%22Oluwawibe+BJ%22">Oluwawibe BJ</searchLink>; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, ChangeLab-Changing Lives; Rm NB 302, Ibadan, Oyo State, 200005, Nigeria.<br /><searchLink fieldCode="AU" term="%22Agbarogi+H%22">Agbarogi H</searchLink>; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, ChangeLab-Changing Lives; Rm NB 302, Ibadan, Oyo State, 200005, Nigeria.<br /><searchLink fieldCode="AU" term="%22Otunla+MT%22">Otunla MT</searchLink>; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, ChangeLab-Changing Lives; Rm NB 302, Ibadan, Oyo State, 200005, Nigeria.<br /><searchLink fieldCode="AU" term="%22Owoeye+O%22">Owoeye O</searchLink>; Department of Anatomy, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Oyo State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Arunsi+UO%22">Arunsi UO</searchLink>; School of Chemistry & Biochemistry, Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, 30332-0400, USA.
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