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Supersaturation mutagenesis reveals adaptive rewiring of essential genes among malaria parasites.

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Title: Supersaturation mutagenesis reveals adaptive rewiring of essential genes among malaria parasites.
Authors: Oberstaller J; Center for Global Health and Interdisciplinary Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA., Xu S; Center for Global Health and Interdisciplinary Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA., Naskar D; Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Zhang M; Center for Global Health and Interdisciplinary Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA., Wang C; Center for Global Health and Interdisciplinary Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA., Gibbons J; Center for Global Health and Interdisciplinary Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA., Pires CV; Center for Global Health and Interdisciplinary Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA., Mayho M; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Otto TD; School of Infection and Immunity, University of Glasgow, Glasgow, UK.; Laboratory of Pathogens and Host Immunity, Centre National de la Recherche Scientifique, and Institut National de la Santé et de la Recherche Médicale, Université de Montpellier, Montpellier, France., Rayner JC; Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Adams JH; Center for Global Health and Interdisciplinary Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA.; Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Source: Science (New York, N.Y.) [Science] 2025 Feb 07; Vol. 387 (6734), pp. eadq7347. Date of Electronic Publication: 2025 Feb 07.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Supersaturation mutagenesis reveals adaptive rewiring of essential genes among malaria parasites.
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  Data: <searchLink fieldCode="AU" term="%22Oberstaller+J%22">Oberstaller J</searchLink>; Center for Global Health and Interdisciplinary Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Xu+S%22">Xu S</searchLink>; Center for Global Health and Interdisciplinary Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Naskar+D%22">Naskar D</searchLink>; Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Zhang+M%22">Zhang M</searchLink>; Center for Global Health and Interdisciplinary Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Center for Global Health and Interdisciplinary Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Gibbons+J%22">Gibbons J</searchLink>; Center for Global Health and Interdisciplinary Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Pires+CV%22">Pires CV</searchLink>; Center for Global Health and Interdisciplinary Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Mayho+M%22">Mayho M</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Otto+TD%22">Otto TD</searchLink>; School of Infection and Immunity, University of Glasgow, Glasgow, UK.; Laboratory of Pathogens and Host Immunity, Centre National de la Recherche Scientifique, and Institut National de la Santé et de la Recherche Médicale, Université de Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Rayner+JC%22">Rayner JC</searchLink>; Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Adams+JH%22">Adams JH</searchLink>; Center for Global Health and Interdisciplinary Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA.; Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
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  Data: <searchLink fieldCode="JN" term="%220404511%22">Science (New York, N.Y.)</searchLink> [Science] 2025 Feb 07; Vol. 387 (6734), pp. eadq7347. <i>Date of Electronic Publication: </i>2025 Feb 07.
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