Differences in cholinergic terminal density in adults with Down syndrome compared to neurotypical controls measured by [18F]-fluoroethoxybenzovesamicol positron emission tomography imaging.

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Title: Differences in cholinergic terminal density in adults with Down syndrome compared to neurotypical controls measured by [18F]-fluoroethoxybenzovesamicol positron emission tomography imaging.
Authors: Russell JK; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA., Conley AC; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA., Boyd BD; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA., Begnoche JP; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA., Schlossberg R; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA., Stranick A; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA., Rosenberg AJ; Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Acosta LMY; Department of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Martin D; Department of Clinical Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Neal Y; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA., Kanel P; Department of Radiology, University of Michigan, Ann Arbor, MI, USA; University of Michigan Morris K. Udall Center of Excellence for Parkinson's Disease Research, Ann Arbor, MI, USA., Albin RL; University of Michigan Morris K. Udall Center of Excellence for Parkinson's Disease Research, Ann Arbor, MI, USA; Department of Neurology, University of Michigan, Ann Arbor, MI, USA; Geriatric Research, Education, and Clinical Center, VAAAHS, Ann Arbor, MI, USA., Rafii MS; Alzheimer's Therapeutic Research Institute, Keck School of Medicine, University of Southern California, San Diego, California, USA., Dumas J; Department of Psychiatry, University of Vermont, Burlington, VT, USA., Newhouse PA; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA; Geriatric Research, Education, and Clinical Center, Veterans Affairs Tennessee Valley Health System, Nashville, TN, USA. Electronic address: paul.newhouse@vanderbilt.edu.
Source: Neurobiology of aging [Neurobiol Aging] 2025 Apr; Vol. 148, pp. 50-60. Date of Electronic Publication: 2025 Jan 30.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 8100437 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-1497 (Electronic) Linking ISSN: 01974580 NLM ISO Abbreviation: Neurobiol Aging Subsets: MEDLINE
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  Data: Differences in cholinergic terminal density in adults with Down syndrome compared to neurotypical controls measured by [<superscript>18</superscript>F]-fluoroethoxybenzovesamicol positron emission tomography imaging.
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  Data: <searchLink fieldCode="AU" term="%22Russell+JK%22">Russell JK</searchLink>; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Conley+AC%22">Conley AC</searchLink>; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Boyd+BD%22">Boyd BD</searchLink>; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Begnoche+JP%22">Begnoche JP</searchLink>; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Schlossberg+R%22">Schlossberg R</searchLink>; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Stranick+A%22">Stranick A</searchLink>; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Rosenberg+AJ%22">Rosenberg AJ</searchLink>; Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Acosta+LMY%22">Acosta LMY</searchLink>; Department of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Martin+D%22">Martin D</searchLink>; Department of Clinical Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Neal+Y%22">Neal Y</searchLink>; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Kanel+P%22">Kanel P</searchLink>; Department of Radiology, University of Michigan, Ann Arbor, MI, USA; University of Michigan Morris K. Udall Center of Excellence for Parkinson's Disease Research, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Albin+RL%22">Albin RL</searchLink>; University of Michigan Morris K. Udall Center of Excellence for Parkinson's Disease Research, Ann Arbor, MI, USA; Department of Neurology, University of Michigan, Ann Arbor, MI, USA; Geriatric Research, Education, and Clinical Center, VAAAHS, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Rafii+MS%22">Rafii MS</searchLink>; Alzheimer's Therapeutic Research Institute, Keck School of Medicine, University of Southern California, San Diego, California, USA.<br /><searchLink fieldCode="AU" term="%22Dumas+J%22">Dumas J</searchLink>; Department of Psychiatry, University of Vermont, Burlington, VT, USA.<br /><searchLink fieldCode="AU" term="%22Newhouse+PA%22">Newhouse PA</searchLink>; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA; Geriatric Research, Education, and Clinical Center, Veterans Affairs Tennessee Valley Health System, Nashville, TN, USA. Electronic address: paul.newhouse@vanderbilt.edu.
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  Data: <searchLink fieldCode="JN" term="%228100437%22">Neurobiology of aging</searchLink> [Neurobiol Aging] 2025 Apr; Vol. 148, pp. 50-60. <i>Date of Electronic Publication: </i>2025 Jan 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8100437 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1558-1497 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201974580%22">01974580 </searchLink><i>NLM ISO Abbreviation: </i>Neurobiol Aging <i>Subsets: </i>MEDLINE
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      – TitleFull: Differences in cholinergic terminal density in adults with Down syndrome compared to neurotypical controls measured by [18F]-fluoroethoxybenzovesamicol positron emission tomography imaging.
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              Text: 2025 Apr
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