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Association of Prior PARP Inhibitor Exposure with Clinical Outcomes after 177Lu-PSMA-617 in Men with Castration-resistant Prostate Cancer and Mutations in DNA Homologous Recombination Repair Genes.

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Title: Association of Prior PARP Inhibitor Exposure with Clinical Outcomes after 177Lu-PSMA-617 in Men with Castration-resistant Prostate Cancer and Mutations in DNA Homologous Recombination Repair Genes.
Authors: Raychaudhuri R; Division of Hematology and Oncology, University of Washington Seattle WA USA; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA., Tuchayi AM; Department of Radiology and Biomedical Imaging, University of California-San Francisco San Francisco CA USA., Low SK; Medical College of Wisconsin Milwaukee WI USA., Arafa AT; University of Minnesota, Masonic Cancer Center Minneapolis MN USA., Graham LS; University of Colorado Medical Center Aurora CO USA., Gulati R; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA., Pritchard CC; Department of Laboratory Medicine and Pathology, University of Washington Seattle WA USA., Montgomery RB; Division of Hematology and Oncology, University of Washington Seattle WA USA; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA., Haffner MC; Department of Laboratory Medicine and Pathology, University of Washington Seattle WA USA; Division of Human Oncology, Fred Hutchinson Cancer Center Seattle WA USA., Nelson PS; Division of Hematology and Oncology, University of Washington Seattle WA USA; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA., Yu EY; Division of Hematology and Oncology, University of Washington Seattle WA USA; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA., Hawley JE; Division of Hematology and Oncology, University of Washington Seattle WA USA; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA., Cheng HH; Division of Hematology and Oncology, University of Washington Seattle WA USA; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA., Mo G; Division of Hematology and Oncology, University of Washington Seattle WA USA., Chen DL; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA; Department of Radiology, University of Washington Seattle WA USA., Antonarakis ES; University of Minnesota, Masonic Cancer Center Minneapolis MN USA., Kilari D; Medical College of Wisconsin Milwaukee WI USA., Hope TA; Department of Radiology and Biomedical Imaging, University of California-San Francisco San Francisco CA USA., Iravani A; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA; Department of Radiology, University of Washington Seattle WA USA., Schweizer MT; Division of Hematology and Oncology, University of Washington Seattle WA USA; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA. Electronic address: schweize@uw.edu.
Source: European urology oncology [Eur Urol Oncol] 2026 Apr; Vol. 9 (2), pp. 430-437. Date of Electronic Publication: 2025 Feb 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101724904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2588-9311 (Electronic) Linking ISSN: 25889311 NLM ISO Abbreviation: Eur Urol Oncol Subsets: MEDLINE
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  Data: Association of Prior PARP Inhibitor Exposure with Clinical Outcomes after <superscript>177</superscript>Lu-PSMA-617 in Men with Castration-resistant Prostate Cancer and Mutations in DNA Homologous Recombination Repair Genes.
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  Data: <searchLink fieldCode="AU" term="%22Raychaudhuri+R%22">Raychaudhuri R</searchLink>; Division of Hematology and Oncology, University of Washington Seattle WA USA; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA.<br /><searchLink fieldCode="AU" term="%22Tuchayi+AM%22">Tuchayi AM</searchLink>; Department of Radiology and Biomedical Imaging, University of California-San Francisco San Francisco CA USA.<br /><searchLink fieldCode="AU" term="%22Low+SK%22">Low SK</searchLink>; Medical College of Wisconsin Milwaukee WI USA.<br /><searchLink fieldCode="AU" term="%22Arafa+AT%22">Arafa AT</searchLink>; University of Minnesota, Masonic Cancer Center Minneapolis MN USA.<br /><searchLink fieldCode="AU" term="%22Graham+LS%22">Graham LS</searchLink>; University of Colorado Medical Center Aurora CO USA.<br /><searchLink fieldCode="AU" term="%22Gulati+R%22">Gulati R</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA.<br /><searchLink fieldCode="AU" term="%22Pritchard+CC%22">Pritchard CC</searchLink>; Department of Laboratory Medicine and Pathology, University of Washington Seattle WA USA.<br /><searchLink fieldCode="AU" term="%22Montgomery+RB%22">Montgomery RB</searchLink>; Division of Hematology and Oncology, University of Washington Seattle WA USA; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA.<br /><searchLink fieldCode="AU" term="%22Haffner+MC%22">Haffner MC</searchLink>; Department of Laboratory Medicine and Pathology, University of Washington Seattle WA USA; Division of Human Oncology, Fred Hutchinson Cancer Center Seattle WA USA.<br /><searchLink fieldCode="AU" term="%22Nelson+PS%22">Nelson PS</searchLink>; Division of Hematology and Oncology, University of Washington Seattle WA USA; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA.<br /><searchLink fieldCode="AU" term="%22Yu+EY%22">Yu EY</searchLink>; Division of Hematology and Oncology, University of Washington Seattle WA USA; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA.<br /><searchLink fieldCode="AU" term="%22Hawley+JE%22">Hawley JE</searchLink>; Division of Hematology and Oncology, University of Washington Seattle WA USA; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA.<br /><searchLink fieldCode="AU" term="%22Cheng+HH%22">Cheng HH</searchLink>; Division of Hematology and Oncology, University of Washington Seattle WA USA; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA.<br /><searchLink fieldCode="AU" term="%22Mo+G%22">Mo G</searchLink>; Division of Hematology and Oncology, University of Washington Seattle WA USA.<br /><searchLink fieldCode="AU" term="%22Chen+DL%22">Chen DL</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA; Department of Radiology, University of Washington Seattle WA USA.<br /><searchLink fieldCode="AU" term="%22Antonarakis+ES%22">Antonarakis ES</searchLink>; University of Minnesota, Masonic Cancer Center Minneapolis MN USA.<br /><searchLink fieldCode="AU" term="%22Kilari+D%22">Kilari D</searchLink>; Medical College of Wisconsin Milwaukee WI USA.<br /><searchLink fieldCode="AU" term="%22Hope+TA%22">Hope TA</searchLink>; Department of Radiology and Biomedical Imaging, University of California-San Francisco San Francisco CA USA.<br /><searchLink fieldCode="AU" term="%22Iravani+A%22">Iravani A</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA; Department of Radiology, University of Washington Seattle WA USA.<br /><searchLink fieldCode="AU" term="%22Schweizer+MT%22">Schweizer MT</searchLink>; Division of Hematology and Oncology, University of Washington Seattle WA USA; Clinical Research Division, Fred Hutchinson Cancer Center Seattle WA USA. Electronic address: schweize@uw.edu.
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  Data: <searchLink fieldCode="JN" term="%22101724904%22">European urology oncology</searchLink> [Eur Urol Oncol] 2026 Apr; Vol. 9 (2), pp. 430-437. <i>Date of Electronic Publication: </i>2025 Feb 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+B%2EV%22">Elsevier B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101724904 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2588-9311 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225889311%22">25889311 </searchLink><i>NLM ISO Abbreviation: </i>Eur Urol Oncol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.euo.2025.01.002
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      – TitleFull: Association of Prior PARP Inhibitor Exposure with Clinical Outcomes after 177Lu-PSMA-617 in Men with Castration-resistant Prostate Cancer and Mutations in DNA Homologous Recombination Repair Genes.
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