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HMGB-1 as a predictor of major bleeding requiring activation of a massive transfusion protocol in severe trauma.

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Title: HMGB-1 as a predictor of major bleeding requiring activation of a massive transfusion protocol in severe trauma.
Authors: Frelich M; Department of Anaesthesiology and Intensive Care Medicine, University Hospital Ostrava, Ostrava, Czech Republic.; Department of Intensive Medicine, Emergency Medicine and Forensic Studies, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic., Bebej M; Department of Anaesthesiology and Intensive Care Medicine, University Hospital Ostrava, Ostrava, Czech Republic., Pavlíček J; Department of Pediatrics, Faculty of Medicine, University Hospital Ostrava, Ostrava University, Ostrava, Czech Republic.; Department of Science and Research, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic., Burša F; Department of Anaesthesiology and Intensive Care Medicine, University Hospital Ostrava, Ostrava, Czech Republic. filip.bursa@fno.cz.; Department of Intensive Medicine, Emergency Medicine and Forensic Studies, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic. filip.bursa@fno.cz., Vodička V; Department of Anaesthesiology and Intensive Care Medicine, University Hospital Ostrava, Ostrava, Czech Republic., Švagera Z; Institute of Laboratory Diagnostics, University Hospital Ostrava, Ostrava, Czech Republic., Kondé A; Department of Applied Mathematics, Faculty of Electrical Engineering and Computer Science, VSB-Technical University of Ostrava, Ostrava, Czech Republic.; Department of the Deputy Director for Science, Research and Education, University Hospital Ostrava, Ostrava, Czech Republic., Jor O; Department of Anaesthesiology and Intensive Care Medicine, University Hospital Ostrava, Ostrava, Czech Republic.; Department of Intensive Medicine, Emergency Medicine and Forensic Studies, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic., Bílená M; Department of Anaesthesiology and Intensive Care Medicine, University Hospital Ostrava, Ostrava, Czech Republic., Romanová T; Department of Anaesthesiology and Intensive Care Medicine, University Hospital Ostrava, Ostrava, Czech Republic.; Department of Intensive Medicine, Emergency Medicine and Forensic Studies, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic., Sklienka P; Department of Anaesthesiology and Intensive Care Medicine, University Hospital Ostrava, Ostrava, Czech Republic.; Department of Intensive Medicine, Emergency Medicine and Forensic Studies, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic.
Source: Scientific reports [Sci Rep] 2025 Feb 07; Vol. 15 (1), pp. 4651. Date of Electronic Publication: 2025 Feb 07.
Publication Type: Journal Article; Observational Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-025-89139-1