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Results of the Phase I/II Study and Preliminary B-cell Gene Signature of Combined Inhibition of Glutamine Metabolism and EGFR in Colorectal Cancer.

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Title: Results of the Phase I/II Study and Preliminary B-cell Gene Signature of Combined Inhibition of Glutamine Metabolism and EGFR in Colorectal Cancer.
Authors: Ciombor KK; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Bae SW; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas., Whisenant JG; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Ayers GD; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee., Sheng Q; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee., Peterson TE; Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee.; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee., Smith GT; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee., Lin K; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Chowdhury S; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Kanikarla Marie P; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Sorokin A; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Cohen AS; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri., Goff LW; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Cardin DB; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Shen JP; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Kopetz S; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Eng C; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Shyr Y; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee., Berlin J; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Manning HC; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2025 Apr 14; Vol. 31 (8), pp. 1437-1448.
Publication Type: Journal Article; Clinical Trial, Phase II; Clinical Trial, Phase I
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Results of the Phase I/II Study and Preliminary B-cell Gene Signature of Combined Inhibition of Glutamine Metabolism and EGFR in Colorectal Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Ciombor+KK%22">Ciombor KK</searchLink>; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Bae+SW%22">Bae SW</searchLink>; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Whisenant+JG%22">Whisenant JG</searchLink>; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Ayers+GD%22">Ayers GD</searchLink>; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Sheng+Q%22">Sheng Q</searchLink>; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Peterson+TE%22">Peterson TE</searchLink>; Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee.; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Smith+GT%22">Smith GT</searchLink>; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Lin+K%22">Lin K</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Chowdhury+S%22">Chowdhury S</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Kanikarla+Marie+P%22">Kanikarla Marie P</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Sorokin+A%22">Sorokin A</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Cohen+AS%22">Cohen AS</searchLink>; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri.<br /><searchLink fieldCode="AU" term="%22Goff+LW%22">Goff LW</searchLink>; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Cardin+DB%22">Cardin DB</searchLink>; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Shen+JP%22">Shen JP</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Kopetz+S%22">Kopetz S</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Eng+C%22">Eng C</searchLink>; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Shyr+Y%22">Shyr Y</searchLink>; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Berlin+J%22">Berlin J</searchLink>; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Manning+HC%22">Manning HC</searchLink>; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas.
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  Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2025 Apr 14; Vol. 31 (8), pp. 1437-1448.
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  Data: Journal Article; Clinical Trial, Phase II; Clinical Trial, Phase I
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502500 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-3265 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210780432%22">10780432 </searchLink><i>NLM ISO Abbreviation: </i>Clin Cancer Res <i>Subsets: </i>MEDLINE
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