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Impact of Mlkl or Ripk3 deletion on age-associated liver inflammation, metabolic health, and lifespan.

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Title: Impact of Mlkl or Ripk3 deletion on age-associated liver inflammation, metabolic health, and lifespan.
Authors: Mohammed S; Stephenson Cancer Center, Department of Biochemistry and Physiology, Oklahoma Center for Geroscience & Brain Aging, University of Oklahoma Health Sciences Center, 975 NE 10th Street, Oklahoma City, OK, 73104, USA.; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Ohene-Marfo P; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Jiang C; Stephenson Cancer Center, Department of Biochemistry and Physiology, Oklahoma Center for Geroscience & Brain Aging, University of Oklahoma Health Sciences Center, 975 NE 10th Street, Oklahoma City, OK, 73104, USA.; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Peng Z; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK, USA., Thadathil N; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Tran A; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Nicklas E; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Bhaskaran S; Stephenson Cancer Center, Department of Biochemistry and Physiology, Oklahoma Center for Geroscience & Brain Aging, University of Oklahoma Health Sciences Center, 975 NE 10th Street, Oklahoma City, OK, 73104, USA.; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Wang D; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Selvarani R; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Singh A; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK, USA., Yang Z; Stephenson Cancer Center, Department of Biochemistry and Physiology, Oklahoma Center for Geroscience & Brain Aging, University of Oklahoma Health Sciences Center, 975 NE 10th Street, Oklahoma City, OK, 73104, USA.; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK, USA., Ahsan N; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK, USA.; Mass Spectrometry, Proteomics and Metabolomics Core Facility, Stephenson Life Sciences Research Center, The University of Oklahoma, Norman, OK, USA., Deepa SS; Stephenson Cancer Center, Department of Biochemistry and Physiology, Oklahoma Center for Geroscience & Brain Aging, University of Oklahoma Health Sciences Center, 975 NE 10th Street, Oklahoma City, OK, 73104, USA. Deepa-Sathyaseelan@ouhsc.edu.; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. Deepa-Sathyaseelan@ouhsc.edu.; Oklahoma Center for Geroscience & Brain Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. Deepa-Sathyaseelan@ouhsc.edu.
Source: GeroScience [Geroscience] 2025 Jun; Vol. 47 (3), pp. 4465-4483. Date of Electronic Publication: 2025 Feb 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Impact of Mlkl or Ripk3 deletion on age-associated liver inflammation, metabolic health, and lifespan.
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  Data: <searchLink fieldCode="AU" term="%22Mohammed+S%22">Mohammed S</searchLink>; Stephenson Cancer Center, Department of Biochemistry and Physiology, Oklahoma Center for Geroscience & Brain Aging, University of Oklahoma Health Sciences Center, 975 NE 10th Street, Oklahoma City, OK, 73104, USA.; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.<br /><searchLink fieldCode="AU" term="%22Ohene-Marfo+P%22">Ohene-Marfo P</searchLink>; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+C%22">Jiang C</searchLink>; Stephenson Cancer Center, Department of Biochemistry and Physiology, Oklahoma Center for Geroscience & Brain Aging, University of Oklahoma Health Sciences Center, 975 NE 10th Street, Oklahoma City, OK, 73104, USA.; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.<br /><searchLink fieldCode="AU" term="%22Peng+Z%22">Peng Z</searchLink>; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK, USA.<br /><searchLink fieldCode="AU" term="%22Thadathil+N%22">Thadathil N</searchLink>; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.<br /><searchLink fieldCode="AU" term="%22Tran+A%22">Tran A</searchLink>; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.<br /><searchLink fieldCode="AU" term="%22Nicklas+E%22">Nicklas E</searchLink>; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.<br /><searchLink fieldCode="AU" term="%22Bhaskaran+S%22">Bhaskaran S</searchLink>; Stephenson Cancer Center, Department of Biochemistry and Physiology, Oklahoma Center for Geroscience & Brain Aging, University of Oklahoma Health Sciences Center, 975 NE 10th Street, Oklahoma City, OK, 73104, USA.; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.<br /><searchLink fieldCode="AU" term="%22Wang+D%22">Wang D</searchLink>; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.<br /><searchLink fieldCode="AU" term="%22Selvarani+R%22">Selvarani R</searchLink>; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.<br /><searchLink fieldCode="AU" term="%22Singh+A%22">Singh A</searchLink>; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK, USA.<br /><searchLink fieldCode="AU" term="%22Yang+Z%22">Yang Z</searchLink>; Stephenson Cancer Center, Department of Biochemistry and Physiology, Oklahoma Center for Geroscience & Brain Aging, University of Oklahoma Health Sciences Center, 975 NE 10th Street, Oklahoma City, OK, 73104, USA.; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK, USA.<br /><searchLink fieldCode="AU" term="%22Ahsan+N%22">Ahsan N</searchLink>; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK, USA.; Mass Spectrometry, Proteomics and Metabolomics Core Facility, Stephenson Life Sciences Research Center, The University of Oklahoma, Norman, OK, USA.<br /><searchLink fieldCode="AU" term="%22Deepa+SS%22">Deepa SS</searchLink>; Stephenson Cancer Center, Department of Biochemistry and Physiology, Oklahoma Center for Geroscience & Brain Aging, University of Oklahoma Health Sciences Center, 975 NE 10th Street, Oklahoma City, OK, 73104, USA. Deepa-Sathyaseelan@ouhsc.edu.; Department of Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. Deepa-Sathyaseelan@ouhsc.edu.; Oklahoma Center for Geroscience & Brain Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. Deepa-Sathyaseelan@ouhsc.edu.
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  Data: <searchLink fieldCode="JN" term="%22101686284%22">GeroScience</searchLink> [Geroscience] 2025 Jun; Vol. 47 (3), pp. 4465-4483. <i>Date of Electronic Publication: </i>2025 Feb 10.
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