Unique mechanisms to increase structural stability and enhance antigen binding in nanobodies.
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| Title: | Unique mechanisms to increase structural stability and enhance antigen binding in nanobodies. |
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| Authors: | Ketaren NE; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY 10065, USA. Electronic address: nketaren@rockefeller.edu., Fridy PC; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY 10065, USA., Malashkevich V; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Sanyal T; Department of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, Quantitative Biosciences Institute, University of California, San Francisco, San Francisco, CA 94143, USA., Brillantes M; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY 10065, USA., Thompson MK; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY 10065, USA., Oren DA; Structural Biology Resource Center, The Rockefeller University, New York, NY 10065, USA., Bonanno JB; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Šali A; Department of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, Quantitative Biosciences Institute, University of California, San Francisco, San Francisco, CA 94143, USA., Almo SC; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Chait BT; Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, NY 10065, USA., Rout MP; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY 10065, USA. Electronic address: rout@rockefeller.edu. |
| Source: | Structure (London, England : 1993) [Structure] 2025 Apr 03; Vol. 33 (4), pp. 677-690.e5. Date of Electronic Publication: 2025 Feb 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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