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Genome-wide profiling of circulating microRNAs in adolescent idiopathic scoliosis and their relation to spinal deformity severity, and disease pathophysiology.

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Title: Genome-wide profiling of circulating microRNAs in adolescent idiopathic scoliosis and their relation to spinal deformity severity, and disease pathophysiology.
Authors: Khatami N; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada.; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada., Caraus I; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada.; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada., Rahaman M; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada., Nepotchatykh E; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada.; Molecular Biology PhD Program, Faculty of Graduate and Postdoctoral Studies, Université de Montréal, Montreal, QC, Canada., Elbakry M; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada.; Biochemistry Division, Chemistry Department, Faculty of Science, Tanta University, Tanta, Egypt., Elremaly W; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada., Franco A; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada., Beauséjour M; Azrieli Research Center, CHU Sainte-Justine, Montreal, QC, Canada.; Department of Surgery, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.; Department of Community Health Sciences, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Longueuil, QC, Canada., Laberge AM; Medical Genetics, Department of Pediatrics, CHU Sainte-Justine and Université de Montréal, Montreal, QC, Canada., Parent S; Azrieli Research Center, CHU Sainte-Justine, Montreal, QC, Canada.; Department of Surgery, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.; Orthopedic Division, CHU Sainte-Justine, Montreal, QC, Canada.; Institut TransMedTech Montreal, CHU Sainte-Justine, Montreal, QC, Canada., Labelle H; Azrieli Research Center, CHU Sainte-Justine, Montreal, QC, Canada.; Department of Surgery, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.; Orthopedic Division, CHU Sainte-Justine, Montreal, QC, Canada.; Institut TransMedTech Montreal, CHU Sainte-Justine, Montreal, QC, Canada., Aubin CÉ; Azrieli Research Center, CHU Sainte-Justine, Montreal, QC, Canada.; Institut TransMedTech Montreal, CHU Sainte-Justine, Montreal, QC, Canada.; Polytechnique Montréal, Montreal, QC, Canada., Lachaine J; Faculty of Pharmacy, Université de Montréal, Montreal, QC, Canada., Moreau A; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada. alain.moreau.hsj@ssss.gouv.qc.ca.; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada. alain.moreau.hsj@ssss.gouv.qc.ca.; Molecular Biology PhD Program, Faculty of Graduate and Postdoctoral Studies, Université de Montréal, Montreal, QC, Canada. alain.moreau.hsj@ssss.gouv.qc.ca.; Institut TransMedTech Montreal, CHU Sainte-Justine, Montreal, QC, Canada. alain.moreau.hsj@ssss.gouv.qc.ca.; Department of Stomatology, Faculty of Dentistry, Université de Montréal, Montreal, QC, Canada. alain.moreau.hsj@ssss.gouv.qc.ca.
Source: Scientific reports [Sci Rep] 2025 Feb 12; Vol. 15 (1), pp. 5305. Date of Electronic Publication: 2025 Feb 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Genome-wide profiling of circulating microRNAs in adolescent idiopathic scoliosis and their relation to spinal deformity severity, and disease pathophysiology.
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  Data: <searchLink fieldCode="AU" term="%22Khatami+N%22">Khatami N</searchLink>; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada.; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Caraus+I%22">Caraus I</searchLink>; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada.; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Rahaman+M%22">Rahaman M</searchLink>; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada.<br /><searchLink fieldCode="AU" term="%22Nepotchatykh+E%22">Nepotchatykh E</searchLink>; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada.; Molecular Biology PhD Program, Faculty of Graduate and Postdoctoral Studies, Université de Montréal, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Elbakry+M%22">Elbakry M</searchLink>; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada.; Biochemistry Division, Chemistry Department, Faculty of Science, Tanta University, Tanta, Egypt.<br /><searchLink fieldCode="AU" term="%22Elremaly+W%22">Elremaly W</searchLink>; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada.<br /><searchLink fieldCode="AU" term="%22Franco+A%22">Franco A</searchLink>; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada.<br /><searchLink fieldCode="AU" term="%22Beauséjour+M%22">Beauséjour M</searchLink>; Azrieli Research Center, CHU Sainte-Justine, Montreal, QC, Canada.; Department of Surgery, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.; Department of Community Health Sciences, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Longueuil, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Laberge+AM%22">Laberge AM</searchLink>; Medical Genetics, Department of Pediatrics, CHU Sainte-Justine and Université de Montréal, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Parent+S%22">Parent S</searchLink>; Azrieli Research Center, CHU Sainte-Justine, Montreal, QC, Canada.; Department of Surgery, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.; Orthopedic Division, CHU Sainte-Justine, Montreal, QC, Canada.; Institut TransMedTech Montreal, CHU Sainte-Justine, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Labelle+H%22">Labelle H</searchLink>; Azrieli Research Center, CHU Sainte-Justine, Montreal, QC, Canada.; Department of Surgery, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.; Orthopedic Division, CHU Sainte-Justine, Montreal, QC, Canada.; Institut TransMedTech Montreal, CHU Sainte-Justine, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Aubin+CÉ%22">Aubin CÉ</searchLink>; Azrieli Research Center, CHU Sainte-Justine, Montreal, QC, Canada.; Institut TransMedTech Montreal, CHU Sainte-Justine, Montreal, QC, Canada.; Polytechnique Montréal, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Lachaine+J%22">Lachaine J</searchLink>; Faculty of Pharmacy, Université de Montréal, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Moreau+A%22">Moreau A</searchLink>; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Azrieli Research Center, CHU Sainte-Justine, room 2.17.027, 3175 Cote-Ste-Catherine Road, Montreal, QC, H3T 1C5, Canada. alain.moreau.hsj@ssss.gouv.qc.ca.; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada. alain.moreau.hsj@ssss.gouv.qc.ca.; Molecular Biology PhD Program, Faculty of Graduate and Postdoctoral Studies, Université de Montréal, Montreal, QC, Canada. alain.moreau.hsj@ssss.gouv.qc.ca.; Institut TransMedTech Montreal, CHU Sainte-Justine, Montreal, QC, Canada. alain.moreau.hsj@ssss.gouv.qc.ca.; Department of Stomatology, Faculty of Dentistry, Université de Montréal, Montreal, QC, Canada. alain.moreau.hsj@ssss.gouv.qc.ca.
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