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Unraveling Alveolar Fibroblast and Activated Myofibroblast Heterogeneity and Differentiation Trajectories During Lung Fibrosis Development and Resolution in Young and Old Mice.

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Title: Unraveling Alveolar Fibroblast and Activated Myofibroblast Heterogeneity and Differentiation Trajectories During Lung Fibrosis Development and Resolution in Young and Old Mice.
Authors: Lingampally A; Department of Respiratory and Critical Care Medicine, Quzhou People's Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, Zhejiang, China.; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Department of Medicine V, Internal Medicine, Infectious Diseases and Infection Control, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Truchi M; UMR CNRS 7275 Inserm 1323, IPMC, FHU-OncoAge, IHU, RespiERA, Sophia Antipolis, Université Côte d'Azur, Valbonne, France., Shi X; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang, China., Zhou Y; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang, China., Vasquez-Pacheco E; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Panagiotidis GD; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Hadzic S; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Koepke J; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Vazquez-Armendariz AI; Transdisciplinary Research Area Life and Health, Organoid Biology, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany., Herold S; Department of Medicine V, Internal Medicine, Infectious Diseases and Infection Control, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Samakovlis C; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Cabrera-Fuentes HA; Centro Interdisciplinario de Investigaciones Biológicas y Humanas (CIINBIOH), Universidad Autónoma Benito Juárez de Oaxaca, Oaxaca, Mexico., Chu X; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang, China., Seeger W; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Department of Medicine V, Internal Medicine, Infectious Diseases and Infection Control, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Zhang JS; Department of Respiratory and Critical Care Medicine, Quzhou People's Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, Zhejiang, China., El Agha E; Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Department of Medicine V, Internal Medicine, Infectious Diseases and Infection Control, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Giessen, Germany.; Institute for Lung Health (ILH), Giessen, Germany., Mari B; UMR CNRS 7275 Inserm 1323, IPMC, FHU-OncoAge, IHU, RespiERA, Sophia Antipolis, Université Côte d'Azur, Valbonne, France., Bellusci S; Department of Respiratory and Critical Care Medicine, Quzhou People's Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, Zhejiang, China.; Laboratory of Extracellular Lung Matrix Remodelling, Department of Internal Medicine, Cardio-Pulmonary Institute and Institute for Lung Health, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany., Chen C; Department of Respiratory and Critical Care Medicine, Quzhou People's Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, Zhejiang, China.
Source: Aging cell [Aging Cell] 2025 May; Vol. 24 (5), pp. e14503. Date of Electronic Publication: 2025 Feb 13.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1474-9726
DOI:10.1111/acel.14503